PL3682247T3 - Proadrenomedulina jako marker nieprawidłowych poziomów płytek krwi - Google Patents
Proadrenomedulina jako marker nieprawidłowych poziomów płytek krwiInfo
- Publication number
- PL3682247T3 PL3682247T3 PL18765659T PL18765659T PL3682247T3 PL 3682247 T3 PL3682247 T3 PL 3682247T3 PL 18765659 T PL18765659 T PL 18765659T PL 18765659 T PL18765659 T PL 18765659T PL 3682247 T3 PL3682247 T3 PL 3682247T3
- Authority
- PL
- Poland
- Prior art keywords
- proadrenomedullin
- marker
- platelet levels
- abnormal platelet
- abnormal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/22—Haematology
- G01N2800/222—Platelet disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17190912 | 2017-09-13 | ||
| EP18161091 | 2018-03-09 | ||
| PCT/EP2018/074725 WO2019053118A1 (en) | 2017-09-13 | 2018-09-13 | PROADRÉNOMÉDULLINE AS A MARKER OF ABNORMAL PLATELET RATES |
| EP18765659.0A EP3682247B1 (en) | 2017-09-13 | 2018-09-13 | Proadrenomedullin as a marker for abnormal platelet levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3682247T3 true PL3682247T3 (pl) | 2022-04-25 |
Family
ID=63517904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18765659T PL3682247T3 (pl) | 2017-09-13 | 2018-09-13 | Proadrenomedulina jako marker nieprawidłowych poziomów płytek krwi |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11327082B2 (pl) |
| EP (3) | EP3971573A1 (pl) |
| JP (1) | JP7346389B2 (pl) |
| CN (1) | CN111094987B (pl) |
| DK (1) | DK3682247T3 (pl) |
| ES (1) | ES2909399T3 (pl) |
| PL (1) | PL3682247T3 (pl) |
| WO (1) | WO2019053118A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022532947A (ja) * | 2019-05-24 | 2022-07-20 | アスチュート メディカル，インコーポレイテッド | Ｃ－ｃモチーフケモカインリガンド１４の測定に基づく腎損傷の評価および処置のための方法 |
| CN114113580A (zh) * | 2020-08-25 | 2022-03-01 | 张曼 | 尿液血栓调节蛋白及其多肽片段在烧伤中的应用 |
| CN119780441A (zh) * | 2024-12-25 | 2025-04-08 | 首都医科大学附属北京胸科医院 | 一种诊断近期及远期结核感染的生物标志物 |
Family Cites Families (39)
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| FR2570703B1 (fr) | 1984-09-26 | 1988-07-08 | Commissariat Energie Atomique | Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents |
| US4882733A (en) | 1987-03-13 | 1989-11-21 | Ford Aerospace Corporation | Method and apparatus for combining encoding and modulation |
| FR2664699B1 (fr) | 1990-07-13 | 1995-08-18 | Cis Bio Int | Procede d'amplification du signal d'emission d'un compose luminescent. |
| DE69602756T2 (de) | 1995-08-18 | 2000-02-10 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Rockville | Funktionelle rolle von adrenomedullin(am) und dem gen-verwandten produkt(pamp) in der menschlichen pathologie und physiologie |
| DE19847690A1 (de) * | 1998-10-15 | 2000-04-20 | Brahms Diagnostica Gmbh | Verfahren und Substanzen für die Diagnose und Therapie von Sepsis und sepsisähnlichen systemischen Infektionen |
| KR100425525B1 (ko) | 2000-11-21 | 2004-03-30 | 재단법인서울대학교산학협력재단 | 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트 |
| AU2002327649A1 (en) * | 2001-09-19 | 2003-04-01 | Mcmaster University | Treatment of sepsis with tafi |
| DE10316583A1 (de) | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| US20060029589A1 (en) * | 2004-06-01 | 2006-02-09 | Hartmut Weiler | Induction of heterozygous FV Leiden carrier status to reduce mortality in sepsis and to prevent organ damage caused by inflammation and/or ischemia-reperfusion injury |
| CA2614507A1 (en) * | 2004-07-09 | 2006-08-17 | Amaox, Ltd. | Immune cell biosensors and methods of using same |
| ES2300681T3 (es) * | 2004-07-22 | 2008-06-16 | Brahms Aktiengesellschaft | Procedimiento para el diagnostico y tratamiento de pacientes criticos con endotelina, agonistas de endotelina y antagonistas de adrenomedulina. |
| US8906857B2 (en) * | 2005-12-01 | 2014-12-09 | B.R.A.H.M.S. Gmbh | Methods for the diagnosis and treatment of critically ill patients with endothelin, endothelin agonists and adrenomedullin antagonists |
| WO2007067983A2 (en) * | 2005-12-09 | 2007-06-14 | Wyeth | Sulfotyrosine specific antibodies and uses therefor |
| DE102006027818A1 (de) * | 2006-06-16 | 2007-12-20 | B.R.A.H.M.S. Aktiengesellschaft | In vitro Multiparameter-Bestimmungsverfahren zur Diagnose und Frühdiagnose von neurodegenerativen Erkrankungen |
| DE102006034142A1 (de) | 2006-07-24 | 2008-01-31 | B.R.A.H.M.S. Aktiengesellschaft | Verfahren zur Steuerung der Therapie von Patienten mit Herzinsuffizienz anhand der vitro Bestimmung von Schwellenwerten von vasoaktiven Peptiden |
| DE102006052916A1 (de) * | 2006-11-08 | 2008-05-15 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Diabetes mellitus mittels MR-proADM |
| US9012151B2 (en) * | 2006-11-09 | 2015-04-21 | B.R.A.H.M.S. Gmbh | Methods of diagnosis and risk stratification of adverse events in post myocardial infarction patients using pro-adrenomedullin |
| DE102006060112A1 (de) | 2006-12-20 | 2008-06-26 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM |
| EP2118665B1 (en) | 2007-03-12 | 2012-04-18 | Biomedica Medizinprodukte GmbH & Co KG | Diagnosis of septic complications |
| CN101796418B (zh) | 2007-09-07 | 2013-05-01 | 苏黎世大学 | 检测分析人体脓毒症的方法 |
| MX2010004615A (es) * | 2007-10-26 | 2010-07-06 | Oklahoma Med Res Found | Anticuerpos monoclonales contra proteina c. activada e inactivada. |
| WO2009062948A1 (en) | 2007-11-16 | 2009-05-22 | Pronota N.V. | Biomarkers and methods for diagnosing, predicting and/or prognosing sepsis and uses thereof |
| ES2643033T3 (es) | 2009-05-05 | 2017-11-21 | B.R.A.H.M.S Gmbh | Estratificación basada en la hormona vasoactiva de los pacientes que sufren de enfermedades relacionadas con la función/disfunción endotelial |
| ITPI20090066A1 (it) * | 2009-05-26 | 2010-11-27 | Consiglio Nazionale Ricerche | Metodo per produrre un dispositivo applicabile a tessuti biologici, in particolare un patch per trattare tessuti danneggiati, e dispositivo ottenuto con tale metodo |
| JP5731489B2 (ja) | 2009-06-05 | 2015-06-10 | ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 呼吸困難を起こした患者における細菌感染の検出 |
| EP2494865A4 (en) * | 2009-09-01 | 2014-05-14 | Aeon Medix Inc | EXTRACELLULAR VESICLES OBTAINED FROM THE DARMFLORA, AND METHOD FOR SEARCHING FOR A DISEASE MODEL, VACCINE AND CANDIDATE AND DIAGNOSTIC METHOD THEREFOR |
| JP5722587B2 (ja) | 2009-10-13 | 2015-05-20 | ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 急性脳卒中または一過性脳虚血発作を有する患者における細菌感染の診断のためのプロカルシトニン及び抗生物質治療のガイダンス |
| CN102822675B (zh) | 2010-03-08 | 2016-06-01 | B.R.A.H.M.S有限公司 | 降钙素原用于在具有非特异性不适的患者中诊断细菌感染和指导抗生素治疗 |
| RU2618437C2 (ru) | 2010-11-01 | 2017-05-03 | Б.Р.А.Х.М.С Гмбх | Оценка прогноза и риска пациентов с неспецифическими жалобами |
| PT2781221T (pt) * | 2011-11-15 | 2020-06-01 | Asahi Kasei Pharma Corp | Medicamento para tratamento e/ou melhoria de sepsia |
| HRP20170427T1 (hr) * | 2011-11-16 | 2017-06-16 | Sphingotec Gmbh | Testovi na adrenomedulin i postupci određivanja zrelog adrenomedulina |
| EP3540440B1 (en) | 2011-12-08 | 2022-09-28 | Astute Medical, Inc. | Methods and uses for evaluating renal injury and renal status |
| EP2657707A1 (en) * | 2012-04-26 | 2013-10-30 | B.R.A.H.M.S GmbH | Biomakers for the diagnosis, prognosis, assessment and therapy stratification syncope |
| ES2755623T3 (es) * | 2012-05-07 | 2020-04-23 | Lsi Medience Corp | Procedimiento de detección de coagulación intravascular diseminada o coagulación intravascular diseminada infecciosa |
| WO2014147153A1 (en) | 2013-03-20 | 2014-09-25 | Sphingotec Gmbh | Adrenomedullin to guide therapy of blood pressure decline |
| WO2015147369A1 (ko) * | 2014-03-27 | 2015-10-01 | 전북대학교산학협력단 | Sirt2 억제제를 포함하는 약학적 조성물 |
| HK1256104A1 (zh) | 2015-11-27 | 2019-09-13 | B.R.A.H.M.S Gmbh | 作为对象的细胞外容量状态的标志物的mr-proadm |
| MX2019000003A (es) | 2016-07-08 | 2019-08-29 | Sphingotec Gmbh | Adrenomodulina para evaluar la congestión en un individuo con insuficiencia cardiaca aguda. |
| JP7104689B2 (ja) | 2016-08-09 | 2022-07-21 | ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 有害事象を示すマーカーとしてのヒストンおよび／またはｐｒｏＡＤＭ |
-
2018
- 2018-09-13 JP JP2020514918A patent/JP7346389B2/ja active Active
- 2018-09-13 ES ES18765659T patent/ES2909399T3/es active Active
- 2018-09-13 US US16/646,798 patent/US11327082B2/en active Active
- 2018-09-13 EP EP21198856.3A patent/EP3971573A1/en active Pending
- 2018-09-13 PL PL18765659T patent/PL3682247T3/pl unknown
- 2018-09-13 EP EP21198828.2A patent/EP3971572A1/en active Pending
- 2018-09-13 DK DK18765659.0T patent/DK3682247T3/da active
- 2018-09-13 WO PCT/EP2018/074725 patent/WO2019053118A1/en not_active Ceased
- 2018-09-13 EP EP18765659.0A patent/EP3682247B1/en active Active
- 2018-09-13 CN CN201880059382.1A patent/CN111094987B/zh active Active
-
2022
- 2022-03-31 US US17/710,329 patent/US12405279B2/en active Active
- 2022-03-31 US US17/710,369 patent/US12000845B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US12000845B2 (en) | 2024-06-04 |
| US20200271675A1 (en) | 2020-08-27 |
| CN111094987A (zh) | 2020-05-01 |
| JP2020533593A (ja) | 2020-11-19 |
| EP3682247A1 (en) | 2020-07-22 |
| CN111094987B (zh) | 2023-10-31 |
| EP3971573A1 (en) | 2022-03-23 |
| JP7346389B2 (ja) | 2023-09-19 |
| US12405279B2 (en) | 2025-09-02 |
| EP3682247B1 (en) | 2022-02-09 |
| ES2909399T3 (es) | 2022-05-06 |
| WO2019053118A1 (en) | 2019-03-21 |
| EP3971572A1 (en) | 2022-03-23 |
| US11327082B2 (en) | 2022-05-10 |
| US20220229076A1 (en) | 2022-07-21 |
| US20220221474A1 (en) | 2022-07-14 |
| DK3682247T3 (da) | 2022-03-21 |
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