PL352213A1 - Antagonistic compounds of the il-8 receptor - Google Patents

Antagonistic compounds of the il-8 receptor

Info

Publication number: PL352213A1
Authority: PL; Poland
Prior art keywords: receptor; antagonistic compounds; antagonistic; compounds
Prior art date: 1999-06-16

Application number

PL00352213A

Inventor

Gregory Martin Benson

Melvin Clarence Rutledge

Katherine L Widdowson

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-16

Filing date

2000-06-15

Publication date

2003-08-11

2000-06-15 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2003-08-11 Publication of PL352213A1 publication Critical patent/PL352213A1/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Oncology (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Diabetes (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

PL00352213A 1999-06-16 2000-06-15 Antagonistic compounds of the il-8 receptor PL352213A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14002499P	1999-06-16	1999-06-16
PCT/US2000/016506 WO2000076501A1 (en)	1999-06-16	2000-06-15	Il-8 receptor antagonists

Publications (1)

Publication Number	Publication Date
PL352213A1 true PL352213A1 (en)	2003-08-11

Family

ID=22489379

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00352213A PL352213A1 (en)	1999-06-16	2000-06-15	Antagonistic compounds of the il-8 receptor

Country Status (19)

Country	Link
EP (1)	EP1185265A4 (en)
JP (1)	JP2003501463A (en)
KR (1)	KR20020015347A (en)
CN (1)	CN1356899A (en)
AR (1)	AR024350A1 (en)
AU (1)	AU766235B2 (en)
BR (1)	BR0011122A (en)
CA (1)	CA2377386A1 (en)
CO (1)	CO5190696A1 (en)
CZ (1)	CZ20014472A3 (en)
HU (1)	HUP0201582A3 (en)
IL (1)	IL145762A0 (en)
MX (1)	MXPA01013005A (en)
NO (1)	NO20016052L (en)
NZ (1)	NZ514696A (en)
PL (1)	PL352213A1 (en)
TR (1)	TR200103638T2 (en)
WO (1)	WO2000076501A1 (en)
ZA (1)	ZA200109480B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1551818B1 (en)	2002-10-09	2009-02-04	Schering Corporation	Thiadiazoledioxides and thiadiazoleoxides as cxc- and cc-chemokine receptor ligands
US7094794B2 (en)	2003-07-28	2006-08-22	Sanofi-Aventis Deutschland Gmbh	Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use
DE10334309A1 (en) *	2003-07-28	2005-03-03	Aventis Pharma Deutschland Gmbh	Substituted thiazole-Benzoisothiazoldioxidderivate, processes for their preparation and their use
CN1839130A (en)	2003-08-21	2006-09-27	Osi制药公司	N-substituted pyrazolyl-amidyl-benzimidazolyl C-KIT inhibitors
US7442709B2 (en)	2003-08-21	2008-10-28	Osi Pharmaceuticals, Inc.	N3-substituted imidazopyridine c-Kit inhibitors
AU2004268949A1 (en)	2003-08-21	2005-03-10	Osi Pharmaceuticals, Inc.	N-substituted benzimidazolyl C-kit inhibitors
DE602004016211D1 (en)	2003-12-19	2008-10-09	Schering Corp	Thiadiazole als cxc- und cc-chemokinrezeptorliganden
JP2008517930A (en)	2004-10-21	2008-05-29	トランステックファーマ，インコーポレイテッド	Bissulfonamide compounds, compositions, and methods of use as agonists of GalR1
JP2008521903A (en)	2004-12-01	2008-06-26	オーエスアイ・ファーマスーティカルズ・インコーポレーテッド	N-substituted benzimidazolyl C-kit inhibitor and combinatorial benzimidazole library
EP2470533A4 (en)	2009-08-24	2013-01-23	Ascepion Pharmaceuticals Inc	5,6-bicyclic heteroaryl-containing urea compounds as kinase inhibitors
EP2377850A1 (en) *	2010-03-30	2011-10-19	Pharmeste S.r.l.	TRPV1 vanilloid receptor antagonists with a bicyclic portion
CN102060780B (en) *	2010-12-27	2014-11-05	雅本化学股份有限公司	Preparation method of 2-(N-substituted).-aminobenzimidazole derivative
CN111116502A (en) *	2018-10-30	2020-05-08	中国石油化工股份有限公司	One-step method for synthesizing benzotriazole

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA921120B (en) *	1991-02-19	1993-01-27	Smithkline Beecham Corp	Cytokine inhibitors
US6300325B1 (en) *	1997-01-23	2001-10-09	Smithkline Beecham Corporation	IL-8 receptor antagonists

2000
- 2000-06-13 CO CO00043846A patent/CO5190696A1/en not_active Application Discontinuation
- 2000-06-14 AR ARP000102922A patent/AR024350A1/en not_active Application Discontinuation
- 2000-06-15 NZ NZ514696A patent/NZ514696A/en unknown
- 2000-06-15 EP EP00941455A patent/EP1185265A4/en not_active Withdrawn
- 2000-06-15 CZ CZ20014472A patent/CZ20014472A3/en unknown
- 2000-06-15 IL IL14576200A patent/IL145762A0/en unknown
- 2000-06-15 CA CA002377386A patent/CA2377386A1/en not_active Abandoned
- 2000-06-15 HU HU0201582A patent/HUP0201582A3/en unknown
- 2000-06-15 CN CN00809090A patent/CN1356899A/en active Pending
- 2000-06-15 WO PCT/US2000/016506 patent/WO2000076501A1/en not_active Ceased
- 2000-06-15 PL PL00352213A patent/PL352213A1/en not_active Application Discontinuation
- 2000-06-15 TR TR2001/03638T patent/TR200103638T2/en unknown
- 2000-06-15 BR BR0011122-8A patent/BR0011122A/en not_active IP Right Cessation
- 2000-06-15 JP JP2001502834A patent/JP2003501463A/en not_active Withdrawn
- 2000-06-15 AU AU56161/00A patent/AU766235B2/en not_active Ceased
- 2000-06-15 MX MXPA01013005A patent/MXPA01013005A/en unknown
- 2000-06-15 KR KR1020017016144A patent/KR20020015347A/en not_active Withdrawn
- 2000-11-16 ZA ZA200109480A patent/ZA200109480B/en unknown
2001
- 2001-12-11 NO NO20016052A patent/NO20016052L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
MXPA01013005A (en)	2002-07-02
EP1185265A1 (en)	2002-03-13
ZA200109480B (en)	2002-11-18
CZ20014472A3 (en)	2002-06-12
KR20020015347A (en)	2002-02-27
AU5616100A (en)	2001-01-02
CA2377386A1 (en)	2000-12-21
HUP0201582A3 (en)	2003-02-28
EP1185265A4 (en)	2004-02-04
JP2003501463A (en)	2003-01-14
NO20016052D0 (en)	2001-12-11
NO20016052L (en)	2001-12-11
CN1356899A (en)	2002-07-03
IL145762A0 (en)	2002-07-25
TR200103638T2 (en)	2002-04-22
AU766235B2 (en)	2003-10-09
HUP0201582A2 (en)	2002-12-28
NZ514696A (en)	2004-03-26
BR0011122A (en)	2002-02-26
WO2000076501A1 (en)	2000-12-21
CO5190696A1 (en)	2002-08-29
AR024350A1 (en)	2002-10-02

Publication	Publication Date	Title
IL146210A0 (en)	2002-07-25	Pyrimidinone compounds
IL145761A0 (en)	2002-07-25	Il-8 receptor antagonists
PL352213A1 (en)	2003-08-11	Antagonistic compounds of the il-8 receptor
AU2001240021A1 (en)	2001-10-30	Diazafluorenone il-8 receptor antagonists
AU2001245724A1 (en)	2001-09-24	Il-8 receptor antagonists
IL146046A0 (en)	2002-07-25	Il-8 receptor antagonists
AU2001241896A1 (en)	2001-09-12	Il-8 receptor antagonists
HUP0201302A3 (en)	2003-02-28	Il-8 receptor antagonists
AU2001253172A1 (en)	2001-10-23	Il-8 receptor antagonists
EP1047424A4 (en)	2002-05-22	Il-8 receptor antagonists
EP1039903A4 (en)	2001-12-05	Il-8 receptor antagonists
EP1194143A4 (en)	2004-02-04	Il-8 receptor antagonists
AU2001245605A1 (en)	2001-09-24	Il-8 receptor antagonists
EP1185270A4 (en)	2004-02-11	Il-8 receptor antagonists
AU5168900A (en)	2000-12-18	Il-8 receptor antagonists
PL352222A1 (en)	2003-08-11	Antagonists of the il-8 receptor
PL346178A1 (en)	2002-01-28	Il-8 receptor antagonists
IL146214A0 (en)	2002-07-25	Il-8 receptor antagonists
AU5622400A (en)	2001-01-02	Il-8 receptor antagonists
EP1237548A4 (en)	2003-07-23	Il-8 receptor antagonists
HK1044474A (en)	2002-10-25	Il-8 receptor antagonists
HK1044473A (en)	2002-10-25	Il-8 receptor antagonists
ZA985975B (en)	1999-01-07	IL-8 receptor antagonists
ZA985813B (en)	1999-03-31	IL-8 receptor antagonists
EP1087661A4 (en)	2003-04-16	Il-8 receptor antagonists

Legal Events

Date	Code	Title	Description
2008-02-29	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)