PL354484A1 - The use of flupirtine for the relief of pain associated with osteoarthritis in cats and dogs - Google Patents

The use of flupirtine for the relief of pain associated with osteoarthritis in cats and dogs

Info

Publication number: PL354484A1
Authority: PL; Poland
Prior art keywords: flupirtine; osteoarthritis; cats; dogs; relief
Prior art date: 1999-08-03

Application number

PL00354484A

Other languages

Polish (pl)

Inventor

Gabriele Endler

Holger Lehmann

Michael Lobisch

Istvan Szelenyi

Original Assignee

Awd Pharma Gmbh & Co.Kg

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-03

Filing date

2000-07-29

Publication date

2004-01-26

2000-07-29 Application filed by Awd Pharma Gmbh & Co.Kg, Bayer Ag filed Critical Awd Pharma Gmbh & Co.Kg

2004-01-26 Publication of PL354484A1 publication Critical patent/PL354484A1/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/76—Salicaceae (Willow family), e.g. poplar
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Natural Medicines & Medicinal Plants (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Mycology (AREA)
Microbiology (AREA)
Medical Informatics (AREA)
Botany (AREA)
Alternative & Traditional Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Physical Education & Sports Medicine (AREA)
Neurology (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Fodder In General (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pyridine Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL00354484A 1999-08-03 2000-07-29 The use of flupirtine for the relief of pain associated with osteoarthritis in cats and dogs PL354484A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14703399P	1999-08-03	1999-08-03
PCT/EP2000/007356 WO2001008682A2 (en)	1999-08-03	2000-07-29	Use of flupirtine for alleviating pain caused by degenerative joint diseases in dogs and cats

Publications (1)

Publication Number	Publication Date
PL354484A1 true PL354484A1 (en)	2004-01-26

Family

ID=22520069

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00354484A PL354484A1 (en)	1999-08-03	2000-07-29	The use of flupirtine for the relief of pain associated with osteoarthritis in cats and dogs

Country Status (20)

Country	Link
EP (1)	EP1242078A2 (en)
JP (1)	JP2003530308A (en)
KR (1)	KR20020040767A (en)
CN (1)	CN1399550A (en)
AR (1)	AR025030A1 (en)
AU (1)	AU7271700A (en)
BR (1)	BR0012942A (en)
CA (1)	CA2314746A1 (en)
CO (1)	CO5180569A1 (en)
CZ (1)	CZ2002411A3 (en)
HR (1)	HRP20020192A2 (en)
HU (1)	HUP0301296A2 (en)
IL (1)	IL147667A0 (en)
MX (1)	MXPA02000997A (en)
NO (1)	NO20020364L (en)
PL (1)	PL354484A1 (en)
RU (1)	RU2002105502A (en)
SK (1)	SK1712002A3 (en)
WO (1)	WO2001008682A2 (en)
ZA (1)	ZA200200493B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10312346A1 (en)	2003-03-20	2004-09-30	Bayer Healthcare Ag	Controlled release system
AU2004298288B2 (en) *	2003-12-16	2011-06-30	Relevare Aust. Pty Ltd	Methods and compositions
CA2550023C (en)	2003-12-16	2011-04-12	Cnsbio Pty Ltd	Treatment of neuropathic pain
US7553858B2 (en) *	2003-12-17	2009-06-30	Meda Pharma Gmbh & Co. Kg	Combination of flupirtine and tramadol
DE102004001558A1 (en) *	2004-01-10	2005-08-18	Bayer Healthcare Ag	Medicinal products for topical application in animals
WO2006024018A2 (en) *	2004-08-24	2006-03-02	Neuromolecular Pharmaceuticals, Inc.	Compositions for treating nociceptive pain
KR101067443B1 (en)	2009-06-23	2011-09-27	여오영	Topical injectable compositions for the treatment of hemorrhoids containing hydroxychloroquine
ITMI20120896A1 (en) *	2012-05-23	2013-11-24	Bongulielmi Reto	CONDROITIN FOR USE IN MEDICINE
CN104523634A (en) *	2014-11-21	2015-04-22	哈尔滨圣吉药业股份有限公司	Flupirtine maleate sustained release tablet and preparation method thereof
RU2680244C1 (en) *	2017-12-28	2019-02-19	Общество С Ограниченной Ответственностью "Валента-Интеллект"	Combination of flupirtine and cyclobenzaprine for treatment of pain syndromes
CN111371527B (en)	2018-12-25	2021-08-13	华为技术有限公司	A data transmission method and communication device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0189788B1 (en) *	1985-01-23	1989-09-13	ASTA Pharma Aktiengesellschaft	Synergistic combination of flupirtin and non-steroidal anti-phlogistics
FI855016L (en) *	1985-06-28	1986-12-29	Degussa	SYNERGISTIC COMBINATION AV FLUPIRTIN OCH 4-ACETAMIDO-PHENOL.
IN172468B (en) *	1990-07-14	1993-08-14	Asta Medica Ag
DE4236752A1 (en) *	1992-10-30	1994-05-05	Asta Medica Ag	Combination preparation of flupirtine and morphine for the treatment of pain and for avoiding morphine addiction

2000
- 2000-07-29 HU HU0301296A patent/HUP0301296A2/en unknown
- 2000-07-29 JP JP2001513412A patent/JP2003530308A/en active Pending
- 2000-07-29 AU AU72717/00A patent/AU7271700A/en not_active Abandoned
- 2000-07-29 BR BR0012942-9A patent/BR0012942A/en not_active IP Right Cessation
- 2000-07-29 EP EP00960383A patent/EP1242078A2/en not_active Withdrawn
- 2000-07-29 RU RU2002105502/15A patent/RU2002105502A/en not_active Application Discontinuation
- 2000-07-29 WO PCT/EP2000/007356 patent/WO2001008682A2/en not_active Ceased
- 2000-07-29 PL PL00354484A patent/PL354484A1/en not_active Application Discontinuation
- 2000-07-29 CN CN00811265A patent/CN1399550A/en active Pending
- 2000-07-29 HR HR20020192A patent/HRP20020192A2/en not_active Application Discontinuation
- 2000-07-29 IL IL14766700A patent/IL147667A0/en unknown
- 2000-07-29 MX MXPA02000997A patent/MXPA02000997A/en unknown
- 2000-07-29 SK SK171-2002A patent/SK1712002A3/en unknown
- 2000-07-29 KR KR1020027001445A patent/KR20020040767A/en not_active Withdrawn
- 2000-07-29 CZ CZ2002411A patent/CZ2002411A3/en unknown
- 2000-08-01 CA CA002314746A patent/CA2314746A1/en not_active Abandoned
- 2000-08-03 AR ARP000104013A patent/AR025030A1/en unknown
- 2000-08-03 CO CO00058363A patent/CO5180569A1/en not_active Application Discontinuation
2002
- 2002-01-23 NO NO20020364A patent/NO20020364L/en not_active Application Discontinuation
- 2002-02-21 ZA ZA200200493A patent/ZA200200493B/en unknown

Also Published As

Publication number	Publication date
MXPA02000997A (en)	2003-10-14
CA2314746A1 (en)	2001-02-03
CN1399550A (en)	2003-02-26
NO20020364D0 (en)	2002-01-23
EP1242078A2 (en)	2002-09-25
IL147667A0 (en)	2002-08-14
HRP20020192A2 (en)	2004-02-29
HUP0301296A2 (en)	2003-08-28
BR0012942A (en)	2002-07-09
AR025030A1 (en)	2002-11-06
NO20020364L (en)	2002-01-23
ZA200200493B (en)	2003-04-30
WO2001008682A3 (en)	2002-07-18
JP2003530308A (en)	2003-10-14
KR20020040767A (en)	2002-05-30
RU2002105502A (en)	2004-03-20
WO2001008682A2 (en)	2001-02-08
SK1712002A3 (en)	2003-03-04
AU7271700A (en)	2001-02-19
CZ2002411A3 (en)	2003-03-12
CO5180569A1 (en)	2002-07-30

Publication	Publication Date	Title
NO995389L (en)	2000-01-04	COX-2 selective carprofen for the treatment of pain and inflammation in dogs
PT1057751E (en)	2003-11-28	CARD CONTAINER TO CONTAIN AND PROVIDE WIRE
BR9710872A (en)	1999-08-17	M-todo for increased growth and yield in plants
EE200100373A (en)	2002-10-15	Benzoheterocycles and their use as MEK inhibitors
DK1141252T3 (en)	2006-06-19	Human delta-5 desaturase gene and uses thereof
BR9708882A (en)	1999-08-03	Triazolyl mercaptidas and their use as microbicides
ID28812A (en)	2001-07-05	ANTIMICROBIAL ENZIMA IN ANIMAL FEED
DE60019490D1 (en)	2005-05-25	Fuel conveyor and treatment device
PL354484A1 (en)	2004-01-26	The use of flupirtine for the relief of pain associated with osteoarthritis in cats and dogs
NO20022890L (en)	2002-08-15	New Heliobacter pylori-binding substances and their use
DE50011452D1 (en)	2005-12-01	POLYALKENALKOHOL-POLYALKOXYLATE AND THEIR USE IN FORCE AND LUBRICANTS
DE69919705D1 (en)	2004-09-30	DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR ANIMAL MEDICINE AS IN COSMETOLOGY
DE69920224D1 (en)	2004-10-21	Urea derivatives for pain relief
ID25431A (en)	2000-10-05	APPLICATOR WITH HEALTH CARE
FI974353L (en)	1997-11-27	Directly applied solution for use against parasites in cattle and sheep
DE50016038D1 (en)	2011-01-05	USE OF NANOSCALANT ANTIMICROBIAL ACTIVE IN BODY DEODORANTIES
NO983953L (en)	1998-10-26	Azole compounds with antimycotic activity for use in human and veterinary medicine
NO306491B1 (en)	1999-11-15	Livestock farming and its use
DE69908592D1 (en)	2003-07-10	Continuous mixing and feeding device
LU90560B1 (en)	2001-11-23	Animal husbandry building - vents
NO20005727L (en)	2001-01-15	Polymer products and their use in oil
ES1044092Y (en)	2000-08-16	DEVICE COLLECTOR OF EXCREMENTS OF CATS AND THE LIKE.
NO974609L (en)	1997-12-04	Azole compounds with antimycotic activity for use in humans and animals
FI4002U1 (en)	1999-06-15	Breeding unit and arrangement in breeding unit
DE69909137D1 (en)	2003-07-31	Polyunsaturated fatty acid derivatives and their use in cancer treatment

Legal Events

Date	Code	Title	Description
2008-03-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)