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PL3402537T3 - Ilościowe obrazowanie pet ekspresji czynnika tkankowego z wykorzystaniem hamowanego czynnika vii aktywnego miejsca znakowanego 18f - Google Patents

Ilościowe obrazowanie pet ekspresji czynnika tkankowego z wykorzystaniem hamowanego czynnika vii aktywnego miejsca znakowanego 18f

Info

Publication number
PL3402537T3
PL3402537T3 PL17738231T PL17738231T PL3402537T3 PL 3402537 T3 PL3402537 T3 PL 3402537T3 PL 17738231 T PL17738231 T PL 17738231T PL 17738231 T PL17738231 T PL 17738231T PL 3402537 T3 PL3402537 T3 PL 3402537T3
Authority
PL
Poland
Prior art keywords
active site
pet imaging
quantitative pet
site inhibited
factor vii
Prior art date
Application number
PL17738231T
Other languages
English (en)
Inventor
Andreas Kjaer
Carsten HAAGEN NIELSEN
Original Assignee
Rigshospitalet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rigshospitalet filed Critical Rigshospitalet
Publication of PL3402537T3 publication Critical patent/PL3402537T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/6408Serine endopeptidases (3.4.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL17738231T 2016-01-15 2017-01-13 Ilościowe obrazowanie pet ekspresji czynnika tkankowego z wykorzystaniem hamowanego czynnika vii aktywnego miejsca znakowanego 18f PL3402537T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201670019 2016-01-15
PCT/DK2017/050006 WO2017121436A1 (en) 2016-01-15 2017-01-13 Quantitative pet imaging of tissue factor expression using 18f-labled active site inhibited factor vii
EP17738231.4A EP3402537B1 (en) 2016-01-15 2017-01-13 Quantitative pet imaging of tissue factor expression using 18f-labelled active site inhibited factor vii

Publications (1)

Publication Number Publication Date
PL3402537T3 true PL3402537T3 (pl) 2021-07-19

Family

ID=59310834

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17738231T PL3402537T3 (pl) 2016-01-15 2017-01-13 Ilościowe obrazowanie pet ekspresji czynnika tkankowego z wykorzystaniem hamowanego czynnika vii aktywnego miejsca znakowanego 18f

Country Status (8)

Country Link
US (1) US20190015532A1 (pl)
EP (1) EP3402537B1 (pl)
AU (1) AU2017206445B2 (pl)
CA (1) CA3010310C (pl)
DK (1) DK3402537T3 (pl)
ES (1) ES2856968T3 (pl)
PL (1) PL3402537T3 (pl)
WO (1) WO2017121436A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6701217B2 (ja) 2014-11-25 2020-05-27 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 生物学的製剤の18f−放射性標識方法および組成物
KR102632418B1 (ko) 2014-11-25 2024-01-31 브리스톨-마이어스 스큅 컴퍼니 영상화를 위한 신규 pd-l1 결합 폴리펩티드
CN109562195A (zh) 2016-06-01 2019-04-02 百时美施贵宝公司 用pd-l1结合多肽进行pet成像
WO2017210335A1 (en) * 2016-06-01 2017-12-07 Bristol-Myers Squibb Company Imaging methods using 18f-radiolabeled biologics

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003390A1 (en) 1988-09-23 1990-04-05 Corvas, Inc. Peptidyl inhibitors of the initiation of coagulation
US5190919A (en) 1989-11-13 1993-03-02 Board Of Regents, The University Of Texas System Antihemostatic factor vii peptides
US5788965A (en) 1991-02-28 1998-08-04 Novo Nordisk A/S Modified factor VII
WO1992015686A1 (en) 1991-02-28 1992-09-17 Zymogenetics, Inc. Modified factor vii
WO1994027631A1 (en) 1993-05-21 1994-12-08 Zymogenetics, Inc. Modified factor vii
US5833982A (en) 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
CA2164422A1 (en) 1993-06-18 1995-01-05 Ross Wentworth Stephens Factor vii-derived peptides
GB9425380D0 (en) 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
US6500934B1 (en) 1996-07-24 2002-12-31 Michael Rush Lerner Bivalent agonists for G-protein coupled receptors
EP1198479B1 (en) 1999-07-01 2008-06-18 Yale University Neovascular-targeted immunoconjugates
AU7270600A (en) 1999-09-20 2001-04-24 Novo Nordisk A/S Bivalent inhibitor of fviia/tf/fxa complex
AU2001254624A1 (en) 2000-05-03 2001-11-12 Novo-Nordisk A/S Human coagulation factor vii variants
EP1319067A2 (en) 2000-09-13 2003-06-18 Novo Nordisk A/S Human coagulation factor vii variants
WO2004007557A2 (en) 2002-07-12 2004-01-22 Novo Nordisk A/S Tf antagonist
JP2006516564A (ja) * 2003-01-22 2006-07-06 ノボ ノルディスク アクティーゼルスカブ Tf結合薬剤及びそれらの使用

Also Published As

Publication number Publication date
DK3402537T3 (da) 2021-03-29
WO2017121436A1 (en) 2017-07-20
CA3010310A1 (en) 2017-07-20
CA3010310C (en) 2022-11-22
EP3402537A1 (en) 2018-11-21
ES2856968T3 (es) 2021-09-28
AU2017206445A1 (en) 2018-07-26
AU2017206445B2 (en) 2019-07-18
EP3402537A4 (en) 2019-08-28
US20190015532A1 (en) 2019-01-17
EP3402537B1 (en) 2021-01-06

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