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PL3324948T3 - Wielowarstwowe mikrocząstki uwalniające związek farmaceutycznie aktywny w płynnej postaci dawkowania - Google Patents

Wielowarstwowe mikrocząstki uwalniające związek farmaceutycznie aktywny w płynnej postaci dawkowania

Info

Publication number
PL3324948T3
PL3324948T3 PL16738185.4T PL16738185T PL3324948T3 PL 3324948 T3 PL3324948 T3 PL 3324948T3 PL 16738185 T PL16738185 T PL 16738185T PL 3324948 T3 PL3324948 T3 PL 3324948T3
Authority
PL
Poland
Prior art keywords
multilayered
dosage form
active compound
pharmaceutically active
liquid dosage
Prior art date
Application number
PL16738185.4T
Other languages
English (en)
Inventor
Federica Ronchi
Jonathan Goole
Karim Amighi
Georges GUILLAUME
Vincent Stephenne
Original Assignee
BE Pharbel Manufacturing
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP15177221.7A external-priority patent/EP3117824A1/en
Priority claimed from BE20165555A external-priority patent/BE1024339B1/fr
Application filed by BE Pharbel Manufacturing filed Critical BE Pharbel Manufacturing
Publication of PL3324948T3 publication Critical patent/PL3324948T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL16738185.4T 2015-07-17 2016-07-13 Wielowarstwowe mikrocząstki uwalniające związek farmaceutycznie aktywny w płynnej postaci dawkowania PL3324948T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15177221.7A EP3117824A1 (en) 2015-07-17 2015-07-17 Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
BE20165555A BE1024339B1 (fr) 2016-07-01 2016-07-01 Microparticules multicouches libérant un composé pharmaceutiquement actif dans une forme pharmaceutique liquide
PCT/EP2016/066597 WO2017012935A1 (en) 2015-07-17 2016-07-13 Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form

Publications (1)

Publication Number Publication Date
PL3324948T3 true PL3324948T3 (pl) 2023-06-26

Family

ID=56409108

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16738185.4T PL3324948T3 (pl) 2015-07-17 2016-07-13 Wielowarstwowe mikrocząstki uwalniające związek farmaceutycznie aktywny w płynnej postaci dawkowania

Country Status (18)

Country Link
US (1) US20190008787A1 (pl)
EP (1) EP3324948B1 (pl)
JP (1) JP6796132B2 (pl)
KR (1) KR102633566B1 (pl)
CN (1) CN108348475B (pl)
AU (1) AU2016294734B2 (pl)
CA (1) CA2992356C (pl)
DK (1) DK3324948T3 (pl)
ES (1) ES2944568T3 (pl)
FI (1) FI3324948T3 (pl)
HR (1) HRP20230250T1 (pl)
HU (1) HUE061861T2 (pl)
LT (1) LT3324948T (pl)
PL (1) PL3324948T3 (pl)
RS (1) RS64088B1 (pl)
SI (1) SI3324948T1 (pl)
SM (1) SMT202300083T1 (pl)
WO (1) WO2017012935A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107638333A (zh) * 2017-09-29 2018-01-30 点铂医疗科技(常州)有限公司 一种茶多酚/壳聚糖微粒及其制备方法
GB201716716D0 (en) 2017-10-12 2017-11-29 Univ Of Hertfordshire Higher Education Corporation Method for coating particles
JP7438113B2 (ja) * 2018-01-03 2024-02-26 フェリング ベスローテン フェンノートシャップ アミノサリチレートの経口液体医薬組成物
CN111789808A (zh) * 2019-04-08 2020-10-20 生达化学制药股份有限公司 口服医药组成物及其结构
KR20220113941A (ko) * 2019-12-11 2022-08-17 에보닉 오퍼레이션스 게엠베하 질환을 치료 또는 예방하는데 사용하기 위한 투여 형태
EP4072532B1 (en) * 2019-12-11 2024-01-24 Evonik Operations GmbH Dosage form for use in treating or preventing of a disease
JP7606825B2 (ja) * 2020-06-15 2024-12-26 東和薬品株式会社 エソメプラゾール顆粒ならびにその製造方法および用途
US12102624B2 (en) * 2020-08-26 2024-10-01 Nivagen Pharmaceuticals, Inc. Pantoprazole compositions and methods
US12409145B2 (en) * 2020-09-10 2025-09-09 Sawai Pharmaceutical Co., Ltd. Granule, preparation containing the granule, production method of the granule, and production method of preparation containing the granule
KR102589344B1 (ko) * 2021-11-16 2023-10-16 오즈온바이오 주식회사 산 민감성 성분을 포함하는 삼투성 제제 조성물
CN115300506A (zh) * 2022-08-11 2022-11-08 南京红地生物科技有限公司 含有坦索罗辛和米拉贝隆的复方制剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
CA2024040C (en) * 1989-08-29 2002-02-19 Karl D. Hargrave Dibenz [b,f] [1,4]oxazepin (and thiazepin)-11 (10h)-ones and-thiones and their use in the prevention or treatment of aids
FR2774288B1 (fr) 1998-01-30 2001-09-07 Ethypharm Sa Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques
NZ513037A (en) * 1999-01-29 2003-05-30 Disphar Internat B Coated sustained release pharmaceutical composition for the release of an agent in the gastrointestinal tract
US20040005362A1 (en) * 2002-07-03 2004-01-08 Rajneesh Taneja Liquid dosage forms of acid labile drugs
US20040006109A1 (en) 2002-07-03 2004-01-08 Rajneesh Taneja Liquid dosage forms of non-enterically coated acid-labile drugs
CA2557791C (en) 2004-03-26 2011-03-08 Eisai R&D Management Co., Ltd. Controlled-release pharmaceutical composition and method for producing the same
US20060134210A1 (en) 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
US20070098746A1 (en) * 2005-11-02 2007-05-03 Nichols William M Multi-layered coating technology for taste masking
WO2011107855A2 (en) * 2010-03-04 2011-09-09 Torrent Pharmaceuticals Limited Sustained release oral liquid suspension dosage form
DE102010052847A1 (de) * 2010-11-29 2012-05-31 Temmler Werke Gmbh Verfahren zur Herstellung einer PPI-haltigen pharmazeutischen Zubereitung
MX2021000431A (es) * 2011-03-23 2022-10-28 Ironshore Pharmaceuticals & Dev Inc Metodos y composiciones para el tratamiento de trastorno por deficit de atencion.

Also Published As

Publication number Publication date
SMT202300083T1 (it) 2023-05-12
EP3324948B1 (en) 2023-02-15
HRP20230250T1 (hr) 2023-04-14
AU2016294734A1 (en) 2018-02-01
KR20180042853A (ko) 2018-04-26
CN108348475A (zh) 2018-07-31
AU2016294734B2 (en) 2021-01-28
CA2992356A1 (en) 2017-01-26
KR102633566B1 (ko) 2024-02-05
RS64088B1 (sr) 2023-04-28
HUE061861T2 (hu) 2023-08-28
WO2017012935A1 (en) 2017-01-26
FI3324948T3 (fi) 2023-05-05
DK3324948T3 (da) 2023-05-08
ES2944568T3 (es) 2023-06-22
JP6796132B2 (ja) 2020-12-02
CN108348475B (zh) 2022-01-04
EP3324948A1 (en) 2018-05-30
US20190008787A1 (en) 2019-01-10
SI3324948T1 (sl) 2023-05-31
CA2992356C (en) 2024-02-13
LT3324948T (lt) 2023-03-27
JP2018521137A (ja) 2018-08-02

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