PL323461A1 - Novel method of obtaining monohydrate of ropivakin hydrochloride - Google Patents

Novel method of obtaining monohydrate of ropivakin hydrochloride

Info

Publication number: PL323461A1
Authority: PL; Poland
Prior art keywords: ropivakin; hydrochloride; novel method; monohydrate; obtaining
Prior art date: 1995-05-16

Application number

PL96323461A

Other versions

PL184767B1 (en

Inventor

Peter Jaksch

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-16

Filing date

1996-04-30

Publication date

1998-03-30

1996-04-30 Application filed by Astra Ab filed Critical Astra Ab

1998-03-30 Publication of PL323461A1 publication Critical patent/PL323461A1/en

2002-12-31 Publication of PL184767B1 publication Critical patent/PL184767B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)

PL96323461A 1995-05-16 1996-04-30 Novel method of obtaining monohydrate of ropivakin hydrochloride PL184767B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9501808A SE9501808D0 (en)	1995-05-16	1995-05-16	New process
PCT/SE1996/000563 WO1996036606A1 (en)	1995-05-16	1996-04-30	New process for the preparation of ropivacaine hydrochloride monohydrate

Publications (2)

Publication Number	Publication Date
PL323461A1 true PL323461A1 (en)	1998-03-30
PL184767B1 PL184767B1 (en)	2002-12-31

Family

ID=20398325

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL96323461A PL184767B1 (en)	1995-05-16	1996-04-30	Novel method of obtaining monohydrate of ropivakin hydrochloride

Country Status (33)

Country	Link
US (1)	US5959112A (en)
EP (1)	EP0828711B1 (en)
JP (1)	JP3079112B2 (en)
KR (1)	KR100425232B1 (en)
CN (1)	CN1121388C (en)
AR (1)	AR002737A1 (en)
AT (1)	ATE207900T1 (en)
AU (1)	AU696875B2 (en)
BR (1)	BR9608820A (en)
CA (1)	CA2219308C (en)
CZ (1)	CZ290576B6 (en)
DE (1)	DE69616543T2 (en)
DK (1)	DK0828711T3 (en)
EE (1)	EE03394B1 (en)
ES (1)	ES2166888T3 (en)
HU (1)	HU221793B1 (en)
IL (1)	IL118178A (en)
IN (1)	IN185146B (en)
IS (1)	IS1832B (en)
MY (1)	MY115018A (en)
NO (1)	NO309035B1 (en)
NZ (1)	NZ308249A (en)
PL (1)	PL184767B1 (en)
PT (1)	PT828711E (en)
RU (1)	RU2167153C2 (en)
SA (1)	SA96160764B1 (en)
SE (1)	SE9501808D0 (en)
SK (1)	SK281812B6 (en)
TR (1)	TR199701362T1 (en)
TW (1)	TW340841B (en)
UA (1)	UA46770C2 (en)
WO (1)	WO1996036606A1 (en)
ZA (1)	ZA963545B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69824632T2 (en)	1997-11-12	2005-06-09	Mitsubishi Chemical Corp.	PURINE DERIVATIVES AND MEDICAMENTS CONTAINING THE SAME AS AN ACTIVE INGREDIENT
DE60006663T2 (en)	1999-05-11	2004-10-07	Mitsubishi Chem Corp	DIHYDRATE OF A PURINE DERIVATIVE, MEDICINES THAT CONTAIN THIS AS AN ACTIVE ACTIVE SUBSTANCE AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION
AU1037701A (en) *	1999-10-20	2001-04-30	Smithkline Beecham Plc	Process for the preparation of 4-(fluorophenyl)piperidine esters
BRPI0104491B8 (en) *	2001-10-10	2021-05-25	Cristalia Produtos Quim Farmaceuticos Ltda	n-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide; process of obtaining the enantiomers; non-racemic mixture of anantiomers and its process of obtaining and pharmaceutical composition.
US20060270708A1 (en) *	2005-05-25	2006-11-30	Navinta Llc	Novel process for preparation of isotonic aqueous injection of ropivacaine
WO2009044404A1 (en) *	2007-10-01	2009-04-09	Ramniwas Goel	Process for the preparation of (s)-ropivacaine hydrochloride monohydrate
CN102093284B (en) *	2010-12-29	2013-05-08	宜昌人福药业有限责任公司	Method for enriching piperidine-2-formanilide optically active compound
WO2014009964A1 (en) *	2012-07-11	2014-01-16	Neon Laboratories Limited	Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide
CN103086954A (en) *	2013-02-04	2013-05-08	山东省医药工业研究所	Method for preparing ropivacaine
CN104003930B (en) *	2014-06-13	2016-06-08	山东金诃药物研究开发有限公司	The preparation method of a kind of hydrochloric acid ropivacaine
CN113105386B (en) *	2021-04-10	2022-11-25	河北一品制药股份有限公司	Industrialized preparation method of ropivacaine hydrochloride monohydrate
CN114524763A (en) *	2022-03-11	2022-05-24	山东科源制药股份有限公司	Method for preparing ropivacaine hydrochloride impurity (R) -N- (2, 6-xylyl) piperidine-2-formamide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE341404B (en) *	1967-05-18	1971-12-27	Sterling Drug Inc
EP0151110B1 (en) *	1983-08-01	1989-03-01	Astra Läkemedel Aktiebolag	L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same
SE451840B (en) *	1986-01-03	1987-11-02	Astra Laekemedel Ab	OPTICALLY PURE MONOHYDRATED OF S - (-) - 1-PROPYL-2 ', 6'-PIPECOLOXYLIDE HYDROCHLORIDE, SET TO PREPARE THIS AND PHARMACEUTICAL PREPARATIONS FOR LOCAL ANCHORING
SU1579455A3 (en) *	1987-07-01	1990-07-15	Астра Лекемедель Актиеболаг (Фирма)	Method of obtaining optically clean 100%sulfuric acid s-(-)1propyl 2ъ,6ъ-pipekol-oxylidid hydrochloride

1995
- 1995-05-16 SE SE9501808A patent/SE9501808D0/en unknown
1996
- 1996-04-19 IN IN837DE1996 patent/IN185146B/en unknown
- 1996-04-30 DE DE69616543T patent/DE69616543T2/en not_active Expired - Lifetime
- 1996-04-30 EE EE9700301A patent/EE03394B1/en unknown
- 1996-04-30 AT AT96914488T patent/ATE207900T1/en active
- 1996-04-30 NZ NZ308249A patent/NZ308249A/en not_active IP Right Cessation
- 1996-04-30 HU HU9900327A patent/HU221793B1/en active IP Right Grant
- 1996-04-30 CA CA002219308A patent/CA2219308C/en not_active Expired - Fee Related
- 1996-04-30 WO PCT/SE1996/000563 patent/WO1996036606A1/en not_active Ceased
- 1996-04-30 TR TR97/01362T patent/TR199701362T1/en unknown
- 1996-04-30 CN CN96195279A patent/CN1121388C/en not_active Expired - Lifetime
- 1996-04-30 SK SK1512-97A patent/SK281812B6/en not_active IP Right Cessation
- 1996-04-30 AU AU57832/96A patent/AU696875B2/en not_active Expired
- 1996-04-30 CZ CZ19973452A patent/CZ290576B6/en not_active IP Right Cessation
- 1996-04-30 PL PL96323461A patent/PL184767B1/en unknown
- 1996-04-30 UA UA97126021A patent/UA46770C2/en unknown
- 1996-04-30 BR BR9608820A patent/BR9608820A/en not_active Application Discontinuation
- 1996-04-30 DK DK96914488T patent/DK0828711T3/en active
- 1996-04-30 JP JP08534738A patent/JP3079112B2/en not_active Expired - Lifetime
- 1996-04-30 KR KR1019970708171A patent/KR100425232B1/en not_active Expired - Lifetime
- 1996-04-30 RU RU97120751/04A patent/RU2167153C2/en active
- 1996-04-30 PT PT96914488T patent/PT828711E/en unknown
- 1996-04-30 ES ES96914488T patent/ES2166888T3/en not_active Expired - Lifetime
- 1996-04-30 EP EP96914488A patent/EP0828711B1/en not_active Expired - Lifetime
- 1996-04-30 US US08/647,994 patent/US5959112A/en not_active Expired - Lifetime
- 1996-05-03 ZA ZA963545A patent/ZA963545B/en unknown
- 1996-05-05 SA SA96160764A patent/SA96160764B1/en unknown
- 1996-05-06 TW TW085105371A patent/TW340841B/en not_active IP Right Cessation
- 1996-05-07 IL IL11817896A patent/IL118178A/en not_active IP Right Cessation
- 1996-05-07 AR ARP960102486A patent/AR002737A1/en unknown
- 1996-05-16 MY MYPI96001857A patent/MY115018A/en unknown
1997
- 1997-11-04 IS IS4607A patent/IS1832B/en unknown
- 1997-11-13 NO NO975220A patent/NO309035B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO975220D0 (en)	1997-11-13
IL118178A0 (en)	1996-09-12
WO1996036606A1 (en)	1996-11-21
ATE207900T1 (en)	2001-11-15
CA2219308A1 (en)	1996-11-21
KR100425232B1 (en)	2004-05-20
NZ308249A (en)	1998-08-26
ZA963545B (en)	1996-11-18
TW340841B (en)	1998-09-21
HK1009805A1 (en)	1999-06-11
EE03394B1 (en)	2001-04-16
TR199701362T1 (en)	1998-05-21
JPH11505242A (en)	1999-05-18
AU696875B2 (en)	1998-09-17
AR002737A1 (en)	1998-04-29
IS1832B (en)	2002-10-30
JP3079112B2 (en)	2000-08-21
KR19990014827A (en)	1999-02-25
SK281812B6 (en)	2001-08-06
NO309035B1 (en)	2000-12-04
ES2166888T3 (en)	2002-05-01
HU221793B1 (en)	2003-01-28
PT828711E (en)	2002-04-29
HUP9900327A2 (en)	1999-05-28
CN1189822A (en)	1998-08-05
SA96160764B1 (en)	2006-07-30
NO975220L (en)	1997-11-13
UA46770C2 (en)	2002-06-17
CZ345297A3 (en)	1998-03-18
US5959112A (en)	1999-09-28
PL184767B1 (en)	2002-12-31
EE9700301A (en)	1998-06-15
CN1121388C (en)	2003-09-17
SK151297A3 (en)	1998-05-06
SE9501808D0 (en)	1995-05-16
EP0828711B1 (en)	2001-10-31
EP0828711A1 (en)	1998-03-18
MY115018A (en)	2003-03-31
RU2167153C2 (en)	2001-05-20
CZ290576B6 (en)	2002-08-14
DK0828711T3 (en)	2002-02-11
IL118178A (en)	2003-07-31
DE69616543D1 (en)	2001-12-06
CA2219308C (en)	2007-12-18
BR9608820A (en)	1999-06-15
IS4607A (en)	1997-11-04
IN185146B (en)	2000-11-25
DE69616543T2 (en)	2002-06-27
AU5783296A (en)	1996-11-29
HUP9900327A3 (en)	2001-05-28

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