PL3297987T3 - Nowe pochodne azetydyny użyteczne jako modulatory korowego neuroprzekaźnictwa katecholaminergicznego - Google Patents
Nowe pochodne azetydyny użyteczne jako modulatory korowego neuroprzekaźnictwa katecholaminergicznegoInfo
- Publication number
- PL3297987T3 PL3297987T3 PL16724046T PL16724046T PL3297987T3 PL 3297987 T3 PL3297987 T3 PL 3297987T3 PL 16724046 T PL16724046 T PL 16724046T PL 16724046 T PL16724046 T PL 16724046T PL 3297987 T3 PL3297987 T3 PL 3297987T3
- Authority
- PL
- Poland
- Prior art keywords
- cathecolaminergic
- neurotransmission
- cortical
- modulators
- derivatives useful
- Prior art date
Links
- 150000001539 azetidines Chemical class 0.000 title 1
- 230000001054 cortical effect Effects 0.000 title 1
- 230000005062 synaptic transmission Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15168373 | 2015-05-20 | ||
| SE1650485 | 2016-04-11 | ||
| PCT/EP2016/061479 WO2016185032A1 (en) | 2015-05-20 | 2016-05-20 | Novel azetidine derivatives useful as modulators of cortical cathecolaminergic neurotransmission |
| EP16724046.4A EP3297987B1 (en) | 2015-05-20 | 2016-05-20 | Novel azetidine derivatives useful as modulators of cortical cathecolaminergic neurotransmission |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3297987T3 true PL3297987T3 (pl) | 2019-10-31 |
Family
ID=56026881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16724046T PL3297987T3 (pl) | 2015-05-20 | 2016-05-20 | Nowe pochodne azetydyny użyteczne jako modulatory korowego neuroprzekaźnictwa katecholaminergicznego |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10087142B2 (pl) |
| EP (1) | EP3297987B1 (pl) |
| JP (1) | JP6679621B2 (pl) |
| KR (1) | KR102595892B1 (pl) |
| CN (1) | CN107646031B (pl) |
| AU (1) | AU2016263510B2 (pl) |
| CA (1) | CA2985710C (pl) |
| DK (1) | DK3297987T3 (pl) |
| ES (1) | ES2730890T3 (pl) |
| HK (1) | HK1245251B (pl) |
| IL (1) | IL255618B (pl) |
| MX (1) | MX365283B (pl) |
| NZ (1) | NZ737451A (pl) |
| PL (1) | PL3297987T3 (pl) |
| PT (1) | PT3297987T (pl) |
| RU (1) | RU2716814C2 (pl) |
| WO (1) | WO2016185032A1 (pl) |
| ZA (1) | ZA201707936B (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107646031B (zh) * | 2015-05-20 | 2020-11-17 | 综合研究实验室瑞典股份公司 | 用作皮质儿茶酚胺能神经传递调节剂的氮杂环丁烷衍生物 |
| FI3541784T3 (fi) | 2016-11-18 | 2023-10-02 | Integrative Res Laboratories Sweden Ab | Uudet atsetidiinijohdannaiset, jotka ovat hyödyllisiä kortikaalisen katekoliamiini-neurotransmission modulaattoreina |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1512969A1 (ru) * | 1988-02-01 | 1989-10-07 | Институт нефтехимического синтеза им.А.В.Топчиева | Способ получени N-алкилазетидинов |
| FR2805818B1 (fr) * | 2000-03-03 | 2002-04-26 | Aventis Pharma Sa | Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant |
| EP1638939A2 (en) | 2003-06-24 | 2006-03-29 | Neurosearch A/S | Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| US7408066B2 (en) * | 2005-06-20 | 2008-08-05 | Schering Corproation | Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists |
| JP2010527980A (ja) * | 2007-05-22 | 2010-08-19 | プロシディオン・リミテッド | 代謝障害を治療するための二環状アリールおよびヘテロアリール化合物 |
| CN101808987A (zh) * | 2007-06-05 | 2010-08-18 | Nsab神经研究瑞典公司分公司 | 作为皮层儿茶酚胺能神经传递调节剂的二取代的苯基吡咯烷 |
| US20110257148A1 (en) * | 2008-11-24 | 2011-10-20 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Novel 1-alkyl-3-hydroxy-3-phenylazetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission |
| US8586572B2 (en) * | 2008-11-24 | 2013-11-19 | Integrative Research Laboratories Sweden Ab | 3-phenyl-azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission |
| WO2010058018A1 (en) * | 2008-11-24 | 2010-05-27 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | 3-phenyl-3-methoxypyrrolidine derivatives as modulators of cortical catecholaminergic neurotransmission |
| KR101273566B1 (ko) * | 2011-09-05 | 2013-06-11 | 한국과학기술연구원 | 신규한 아제티딘 유도체 및 이를 함유하는 항우울제 조성물 |
| CA2853097A1 (en) * | 2011-10-24 | 2013-05-02 | Abbvie Inc. | Novel trpv3 modulators |
| KR101871732B1 (ko) * | 2013-05-09 | 2018-06-27 | 스촨 하이스코 파마수티컬 씨오., 엘티디 | 페놀유도체, 이의 제조방법 및 의약에서의 이의 용도 |
| JP6539724B2 (ja) * | 2014-08-27 | 2019-07-03 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｔａａｒリガンドとしての置換アゼチジン誘導体 |
| CN107646031B (zh) * | 2015-05-20 | 2020-11-17 | 综合研究实验室瑞典股份公司 | 用作皮质儿茶酚胺能神经传递调节剂的氮杂环丁烷衍生物 |
-
2016
- 2016-05-20 CN CN201680027679.0A patent/CN107646031B/zh active Active
- 2016-05-20 NZ NZ737451A patent/NZ737451A/en unknown
- 2016-05-20 PT PT16724046T patent/PT3297987T/pt unknown
- 2016-05-20 EP EP16724046.4A patent/EP3297987B1/en active Active
- 2016-05-20 WO PCT/EP2016/061479 patent/WO2016185032A1/en not_active Ceased
- 2016-05-20 RU RU2017140419A patent/RU2716814C2/ru active
- 2016-05-20 DK DK16724046.4T patent/DK3297987T3/da active
- 2016-05-20 US US15/574,796 patent/US10087142B2/en active Active
- 2016-05-20 AU AU2016263510A patent/AU2016263510B2/en active Active
- 2016-05-20 CA CA2985710A patent/CA2985710C/en active Active
- 2016-05-20 HK HK18104487.2A patent/HK1245251B/en unknown
- 2016-05-20 PL PL16724046T patent/PL3297987T3/pl unknown
- 2016-05-20 JP JP2017560182A patent/JP6679621B2/ja active Active
- 2016-05-20 ES ES16724046T patent/ES2730890T3/es active Active
- 2016-05-20 MX MX2017014577A patent/MX365283B/es active IP Right Grant
- 2016-05-20 KR KR1020177033560A patent/KR102595892B1/ko active Active
-
2017
- 2017-11-13 IL IL255618A patent/IL255618B/en active IP Right Grant
- 2017-11-22 ZA ZA2017/07936A patent/ZA201707936B/en unknown
-
2018
- 2018-09-27 US US16/144,076 patent/US10287247B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2017140419A3 (pl) | 2019-07-26 |
| NZ737451A (en) | 2022-01-28 |
| MX365283B (es) | 2019-05-29 |
| PT3297987T (pt) | 2019-06-19 |
| MX2017014577A (es) | 2018-06-11 |
| WO2016185032A1 (en) | 2016-11-24 |
| ZA201707936B (en) | 2020-01-29 |
| HK1245251B (en) | 2020-04-24 |
| US20180141903A1 (en) | 2018-05-24 |
| AU2016263510B2 (en) | 2020-03-12 |
| RU2716814C2 (ru) | 2020-03-17 |
| CA2985710C (en) | 2023-07-25 |
| JP6679621B2 (ja) | 2020-04-15 |
| US10087142B2 (en) | 2018-10-02 |
| KR102595892B1 (ko) | 2023-10-31 |
| IL255618A (en) | 2018-01-31 |
| US10287247B2 (en) | 2019-05-14 |
| CA2985710A1 (en) | 2016-11-24 |
| RU2017140419A (ru) | 2019-06-20 |
| JP2018520100A (ja) | 2018-07-26 |
| ES2730890T3 (es) | 2019-11-13 |
| US20190031606A1 (en) | 2019-01-31 |
| EP3297987A1 (en) | 2018-03-28 |
| CN107646031A (zh) | 2018-01-30 |
| IL255618B (en) | 2020-02-27 |
| EP3297987B1 (en) | 2019-05-15 |
| KR20180004742A (ko) | 2018-01-12 |
| CN107646031B (zh) | 2020-11-17 |
| AU2016263510A1 (en) | 2017-12-07 |
| DK3297987T3 (da) | 2019-06-17 |
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