PL3176164T3 - Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem - Google Patents
Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciemInfo
- Publication number
- PL3176164T3 PL3176164T3 PL15826775T PL15826775T PL3176164T3 PL 3176164 T3 PL3176164 T3 PL 3176164T3 PL 15826775 T PL15826775 T PL 15826775T PL 15826775 T PL15826775 T PL 15826775T PL 3176164 T3 PL3176164 T3 PL 3176164T3
- Authority
- PL
- Poland
- Prior art keywords
- benzothiazepine
- pharmaceutical composition
- same
- composition prepared
- optical isomer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014155068 | 2014-07-30 | ||
| EP15826775.7A EP3176164B1 (en) | 2014-07-30 | 2015-07-17 | Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same |
| PCT/JP2015/070488 WO2016017448A1 (ja) | 2014-07-30 | 2015-07-17 | １，４－ベンゾチアゼピン－１－オキシド誘導体の光学異性体、及びそれを用いた医薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3176164T3 true PL3176164T3 (pl) | 2020-05-18 |
Family
ID=55217353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15826775T PL3176164T3 (pl) | 2014-07-30 | 2015-07-17 | Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10071996B2 (pl) |
| EP (1) | EP3176164B1 (pl) |
| JP (1) | JP6574773B2 (pl) |
| KR (1) | KR102091211B1 (pl) |
| CN (1) | CN106795148B (pl) |
| AU (1) | AU2015297705B2 (pl) |
| CA (1) | CA2956699C (pl) |
| DK (1) | DK3176164T3 (pl) |
| ES (1) | ES2750580T3 (pl) |
| PL (1) | PL3176164T3 (pl) |
| TW (1) | TWI572603B (pl) |
| WO (1) | WO2016017448A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2965277T3 (es) * | 2016-06-27 | 2024-04-11 | Glaxosmithkline Ip No 2 Ltd | Métodos de síntesis |
| CN111447932A (zh) * | 2017-12-11 | 2020-07-24 | 埃塔斯制药株式会社 | 含有1,4-苯并硫氮杂*-1-氧化物衍生物的光学异构体的肾功能障碍的改善药 |
| TWI827866B (zh) * | 2019-07-22 | 2024-01-01 | 日商埃塔斯製藥股份有限公司 | 有光學活性的1,4-苯並硫氮呯-1-氧化物衍生物的製造方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS488825Y1 (pl) | 1970-06-12 | 1973-03-08 | ||
| GB9009389D0 (en) | 1990-04-26 | 1990-06-20 | Smith Kline French Lab | Treatment |
| JP2703408B2 (ja) | 1990-12-28 | 1998-01-26 | 麒麟麦酒株式会社 | １，４‐ベンゾチアゼピン誘導体 |
| HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
| ATE314852T1 (de) | 1998-12-28 | 2006-02-15 | Noboru Kaneko | Verwendung von 1,4-benzothiazepinen zur herstellung eines medikaments zur behandlung der vorhof-fibrillation |
| JP4064027B2 (ja) | 1998-12-28 | 2008-03-19 | 金子 昇 | 心房細動治療薬 |
| ATE298575T1 (de) | 1999-05-19 | 2005-07-15 | Noboru Kaneko | Verwendung von 1,4-benzothiazepinderivaten als medikamente zur überwindung der toleranz für carcinostatika |
| JP4041642B2 (ja) | 1999-05-19 | 2008-01-30 | 昇 金子 | 制癌剤耐性克服剤および制癌剤効果増強剤 |
| JP2004505930A (ja) | 2000-08-07 | 2004-02-26 | ラボラトワール・グラクソスミスクライン・ソシエテ・パール・アクシオン・シンプリフィエ | 心房細動の予防または治療のための薬物の製造における５ｈｔ４受容体アンタゴニストの使用 |
| JP2003095977A (ja) | 2001-09-21 | 2003-04-03 | Masafumi Yano | 筋肉収縮・弛緩機能障害関連疾患の治療又は予防剤 |
| EP1743895A4 (en) | 2004-04-28 | 2010-06-16 | Aetas Pharma Co Ltd | MUSCLE RELIEF ACCELERATOR AND THERAPEUTIC AGENT AGAINST MUSCLE TISSUE DISEASES SUCH AS MUSCLE RELAXATION ERRORS |
| WO2007053610A2 (en) | 2005-11-01 | 2007-05-10 | The Regents Of The University Of California | Methods of treating atrial fibrillation wtih pirfenidone |
| JP2009542624A (ja) | 2006-07-05 | 2009-12-03 | ルピン・リミテッド | スルホキシド化合物の光学的に純粋な又は光学的に富化されたエナンチオマーの調製方法 |
| EP2402333B1 (en) * | 2009-02-25 | 2013-06-26 | Noboru Kaneko | 1,4-benzothiazepine-1-oxide derivative and pharmaceutical composition utilizing the same |
| WO2010114562A1 (en) * | 2009-04-03 | 2010-10-07 | Sequel Pharmaceuticals, Inc. | Improved methods of administration of k201 (jtv-519) (4-[3-{1-(4-benzyl) piperidinyl}propionyl]-7-methoxy 2, 3, 4, 5-tetrahydro-1, 4-benzothiazepine monohydrochloride) |
| FR2963790B1 (fr) | 2010-08-11 | 2012-09-28 | Pf Medicament | Docosahexaeneoate de panthenyle et son utilisation dans le traitement et la prevention des maladies cardiovasculaires |
| JP2012184225A (ja) | 2011-02-18 | 2012-09-27 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
| EP2708535A1 (en) | 2012-05-11 | 2014-03-19 | Les Laboratoires Servier | Agents for treating disorders involving modulation of ryanodine receptors |
-
2015
- 2015-07-17 JP JP2016538270A patent/JP6574773B2/ja active Active
- 2015-07-17 KR KR1020177003192A patent/KR102091211B1/ko active Active
- 2015-07-17 CN CN201580040674.7A patent/CN106795148B/zh active Active
- 2015-07-17 EP EP15826775.7A patent/EP3176164B1/en active Active
- 2015-07-17 AU AU2015297705A patent/AU2015297705B2/en active Active
- 2015-07-17 ES ES15826775T patent/ES2750580T3/es active Active
- 2015-07-17 CA CA2956699A patent/CA2956699C/en active Active
- 2015-07-17 DK DK15826775T patent/DK3176164T3/da active
- 2015-07-17 WO PCT/JP2015/070488 patent/WO2016017448A1/ja not_active Ceased
- 2015-07-17 US US15/329,827 patent/US10071996B2/en active Active
- 2015-07-17 PL PL15826775T patent/PL3176164T3/pl unknown
- 2015-07-23 TW TW104123852A patent/TWI572603B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3176164A4 (en) | 2018-01-03 |
| DK3176164T3 (da) | 2019-10-28 |
| WO2016017448A1 (ja) | 2016-02-04 |
| JPWO2016017448A1 (ja) | 2017-05-18 |
| US10071996B2 (en) | 2018-09-11 |
| TW201607945A (zh) | 2016-03-01 |
| CN106795148A (zh) | 2017-05-31 |
| ES2750580T3 (es) | 2020-03-26 |
| TWI572603B (zh) | 2017-03-01 |
| CA2956699C (en) | 2020-09-29 |
| EP3176164A1 (en) | 2017-06-07 |
| CN106795148B (zh) | 2019-12-10 |
| KR20170031712A (ko) | 2017-03-21 |
| KR102091211B1 (ko) | 2020-03-19 |
| US20170247362A1 (en) | 2017-08-31 |
| EP3176164B1 (en) | 2019-08-21 |
| AU2015297705A1 (en) | 2017-03-02 |
| CA2956699A1 (en) | 2016-02-04 |
| JP6574773B2 (ja) | 2019-09-11 |
| AU2015297705B2 (en) | 2019-12-19 |
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