[go: up one dir, main page]

PL3141617T3 - Sposoby przewidywania wyniku w związku z nowotworem u pacjenta przez analizowanie ekspresji genów - Google Patents

Sposoby przewidywania wyniku w związku z nowotworem u pacjenta przez analizowanie ekspresji genów

Info

Publication number
PL3141617T3
PL3141617T3 PL16193596T PL16193596T PL3141617T3 PL 3141617 T3 PL3141617 T3 PL 3141617T3 PL 16193596 T PL16193596 T PL 16193596T PL 16193596 T PL16193596 T PL 16193596T PL 3141617 T3 PL3141617 T3 PL 3141617T3
Authority
PL
Poland
Prior art keywords
outcome
predicting
cancer
patient
methods
Prior art date
Application number
PL16193596T
Other languages
English (en)
Inventor
Jérôme GALON
Franck Pages
Bernard Mlecnik
Herve Fridman
Original Assignee
Assist Publique Hopitaux De Paris
Inst Nat Sante Rech Med
Univ Paris Descartes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Assist Publique Hopitaux De Paris, Inst Nat Sante Rech Med, Univ Paris Descartes filed Critical Assist Publique Hopitaux De Paris
Publication of PL3141617T3 publication Critical patent/PL3141617T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Primary Health Care (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL16193596T 2011-01-11 2012-01-11 Sposoby przewidywania wyniku w związku z nowotworem u pacjenta przez analizowanie ekspresji genów PL3141617T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP11305024 2011-01-11
US201161434514P 2011-01-20 2011-01-20
PCT/EP2012/050358 WO2012095448A1 (en) 2011-01-11 2012-01-11 Methods for predicting the outcome of a cancer in a patient by analysing gene expression
EP12700803.5A EP2663650B1 (en) 2011-01-11 2012-01-11 Methods for predicting the outcome of a cancer in a patient by analysing gene expression
EP16193596.0A EP3141617B1 (en) 2011-01-11 2012-01-11 Methods for predicting the outcome of a cancer in a patient by analysing gene expression

Publications (1)

Publication Number Publication Date
PL3141617T3 true PL3141617T3 (pl) 2019-04-30

Family

ID=43778393

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16193596T PL3141617T3 (pl) 2011-01-11 2012-01-11 Sposoby przewidywania wyniku w związku z nowotworem u pacjenta przez analizowanie ekspresji genów

Country Status (8)

Country Link
US (4) US20140018255A1 (pl)
EP (2) EP3141617B1 (pl)
JP (1) JP6505656B2 (pl)
DK (1) DK3141617T3 (pl)
ES (1) ES2609249T3 (pl)
LT (1) LT3141617T (pl)
PL (1) PL3141617T3 (pl)
WO (1) WO2012095448A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2880180B1 (en) * 2012-08-06 2018-10-03 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods and kits for screening patients with a cancer
US11984200B2 (en) 2017-06-13 2024-05-14 Bostongene Corporation Systems and methods for generating, visualizing and classifying molecular functional profiles
US10704093B2 (en) 2017-07-05 2020-07-07 The Regents Of The Universtiy Of California Assay for pre-operative prediction of organ function recovery
GB201810190D0 (en) * 2018-06-21 2018-08-08 Cancer Research Tech Ltd Prognostic and treatment response predictive method
WO2020245155A1 (en) 2019-06-03 2020-12-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for modulating a treatment regimen
JP2023500054A (ja) 2019-11-07 2023-01-04 オンクセルナ セラピューティクス,インコーポレイテッド 腫瘍微小環境の分類
JP7741831B2 (ja) 2020-06-30 2025-09-18 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 術前補助療法及び根治手術後の固形がんを患っている患者の再発及び/又は死亡のリスクを予測するための方法
CN115997123A (zh) 2020-06-30 2023-04-21 国家医疗保健研究所 用于预测实体癌患者在术前辅助治疗后复发和/或死亡风险的方法
WO2022074107A1 (en) * 2020-10-09 2022-04-14 Worldwide Innovative Network Novel prediction method and gene signatures for the treatment of cancer
US20250035635A1 (en) 2022-03-17 2025-01-30 Institut National De La Sante Et De La Recherche Medicale Methods for predicting response to an immunotherapeutic treatment in a patient with a cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6773883B2 (en) * 2000-07-31 2004-08-10 The Brigham & Women's Hospital, Inc. Prognostic classification of endometrial cancer
WO2005054508A2 (en) * 2003-12-01 2005-06-16 Ipsogen Gene expression profiling of colon cancer by dna microarrays and correlation with survival and histoclinical parameters
EP1704416A2 (en) * 2004-01-16 2006-09-27 Ipsogen Protein expression profiling and breast cancer prognosis
WO2005111076A1 (en) * 2004-05-12 2005-11-24 Institut National De La Sante Et De La Recherche Medicale (Inserm) Nectin 4 (n4) as a marker for cancer prognosis
JP4370409B2 (ja) * 2005-06-22 2009-11-25 国立大学法人東北大学 がんの予後予測方法
EP1777523A1 (en) * 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method
CN101454668A (zh) * 2005-11-14 2009-06-10 拜耳医药保健有限责任公司 癌症预测与预后以及监测癌症治疗的方法
EP2061885A4 (en) * 2006-09-15 2011-03-09 Univ Mcgill BREAST CANCER INDICATOR DERIVED FROM STROMA
US20110318370A1 (en) * 2008-11-27 2011-12-29 Andreas Bikfalvi Cxcl4l1 as a biomarker of pancreatic cancer
EP2213682A1 (en) * 2009-01-30 2010-08-04 Institut Curie TSLP promotes immune evasion and persistence of viruses
WO2010144192A1 (en) * 2009-05-05 2010-12-16 Children's Medical Center Corporation Prognosis indicators for solid human tumors

Also Published As

Publication number Publication date
EP3141617A3 (en) 2017-04-19
US20150225799A1 (en) 2015-08-13
JP6505656B2 (ja) 2019-04-24
EP3141617A2 (en) 2017-03-15
US20200248269A1 (en) 2020-08-06
EP3141617B1 (en) 2018-11-14
JP2017060515A (ja) 2017-03-30
ES2609249T3 (es) 2017-04-19
WO2012095448A1 (en) 2012-07-19
US20140018255A1 (en) 2014-01-16
JP6051166B2 (ja) 2016-12-27
JP2014506782A (ja) 2014-03-20
EP2663650B1 (en) 2016-11-09
EP2663650A1 (en) 2013-11-20
DK3141617T3 (en) 2019-02-25
LT3141617T (lt) 2019-02-25
US20170175207A1 (en) 2017-06-22

Similar Documents

Publication Publication Date Title
IL233709A (en) A method to predict the likelihood of clinical outcome for a patient with prostate cancer
EP2686689A4 (en) METHODS OF PREDICTING RISK OF UNDESIRABLE CLINICAL RESULT
PL3141617T3 (pl) Sposoby przewidywania wyniku w związku z nowotworem u pacjenta przez analizowanie ekspresji genów
GB2503623B (en) A method for predicting a result of a treatment of keratinous fibers
ZA201404655B (en) Methods for improving medical therapies
EP2768983A4 (en) METHODS OF IDENTIFYING MUTATIONS ASSOCIATED WITH DISEASES
EP2720719A4 (en) METHOD FOR SELECTION OF THERAPEUTIC INDICATIONS
ZA201308111B (en) Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
IL229254A0 (en) Therapeutic antibodies
GB201102014D0 (en) Method for predicting risk of developing cancer
GB2501640B (en) Product selection using genetic analysis
GB201100150D0 (en) Mutational analysis
GB201100282D0 (en) Biological methods
EP2721180A4 (en) GENETIC VARIANTS FOR PREDICTING THE RISK OF BREAST CANCER
EP2685257A4 (en) METHOD OF ANALYSIS
IL228644A0 (en) Cancer treatment methods
GB2488349B (en) Location data analysis
IL232493A0 (en) A method for quantifying cancer treatment
ZA201502595B (en) Therapeutic methods
EP2791843A4 (en) PROGRAMMABLE CELL MODEL FOR DETERMINING TREATMENTS AGAINST CANCER
GB201120989D0 (en) Genetic test
EP2785870A4 (en) SMYD2 AS A TARGET GENE FOR ANTICANCER THERAPY AND THE DIAGNOSIS OF CANCER
EP2714903A4 (en) SUV39H2 AS A TARGET GENE IN ANTICANCER THERAPY AND FOR THE DIAGNOSIS OF CANCER
PT3141617T (pt) Métodos para prever o desfecho de cancro num doente através da análise da expressão de genes
GB201106630D0 (en) Cancer therapy