PL2920150T3 - Sposób wytwarzania kwasu 2-trifluorometyloizonikotynowego i estrów - Google Patents
Sposób wytwarzania kwasu 2-trifluorometyloizonikotynowego i estrówInfo
- Publication number
- PL2920150T3 PL2920150T3 PL13792327T PL13792327T PL2920150T3 PL 2920150 T3 PL2920150 T3 PL 2920150T3 PL 13792327 T PL13792327 T PL 13792327T PL 13792327 T PL13792327 T PL 13792327T PL 2920150 T3 PL2920150 T3 PL 2920150T3
- Authority
- PL
- Poland
- Prior art keywords
- esters
- preparation
- isonicotinic acid
- trifluoromethyl isonicotinic
- trifluoromethyl
- Prior art date
Links
- BZFGKBQHQJVAHS-UHFFFAOYSA-N 2-(trifluoromethyl)pyridine-4-carboxylic acid Chemical compound OC(=O)C1=CC=NC(C(F)(F)F)=C1 BZFGKBQHQJVAHS-UHFFFAOYSA-N 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Health & Medical Sciences (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12193065 | 2012-11-16 | ||
| EP13792327.2A EP2920150B1 (en) | 2012-11-16 | 2013-11-13 | Process for the preparation of 2-trifluoromethyl isonicotinic acid and esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2920150T3 true PL2920150T3 (pl) | 2017-11-30 |
Family
ID=47189790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13792327T PL2920150T3 (pl) | 2012-11-16 | 2013-11-13 | Sposób wytwarzania kwasu 2-trifluorometyloizonikotynowego i estrów |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9481650B2 (pl) |
| EP (1) | EP2920150B1 (pl) |
| JP (1) | JP6267221B2 (pl) |
| KR (1) | KR20150083864A (pl) |
| CN (1) | CN104781236B (pl) |
| AU (1) | AU2013346882B2 (pl) |
| BR (1) | BR112015010120A2 (pl) |
| CA (1) | CA2885155C (pl) |
| ES (1) | ES2641376T3 (pl) |
| HR (1) | HRP20171346T1 (pl) |
| IL (1) | IL237904A (pl) |
| MX (1) | MX362274B (pl) |
| MY (1) | MY170491A (pl) |
| NZ (1) | NZ706266A (pl) |
| PL (1) | PL2920150T3 (pl) |
| RU (1) | RU2654486C2 (pl) |
| SG (1) | SG11201503573WA (pl) |
| SI (1) | SI2920150T1 (pl) |
| WO (1) | WO2014076127A1 (pl) |
| ZA (1) | ZA201503201B (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240002341A1 (en) * | 2020-10-23 | 2024-01-04 | Vertellus Holdings Llc | Methods of making nicotinic acid derivatives |
| CN115724793A (zh) * | 2022-11-07 | 2023-03-03 | 山西永津集团有限公司 | 一种2-溴异烟腈的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002221080A1 (en) * | 2000-12-08 | 2002-06-18 | Masami Kusaka | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparingthe same and use thereof |
| JP4160295B2 (ja) * | 2000-12-08 | 2008-10-01 | 武田薬品工業株式会社 | ３−ピリジル基を有する置換チアゾール誘導体、その製造法および用途 |
| TW200307669A (en) * | 2002-04-15 | 2003-12-16 | Nippon Soda Co | Novel oxime o-ether compound, production process thereof, and agricultural or horticultural bactericide |
| CA2577947A1 (en) * | 2004-08-31 | 2006-03-09 | Banyu Pharmaceutical Co., Ltd. | Novel substituted imidazole derivative |
| US7745477B2 (en) * | 2006-02-07 | 2010-06-29 | Hoffman-La Roche Inc. | Heteroaryl and benzyl amide compounds |
| WO2010100050A1 (en) * | 2009-03-05 | 2010-09-10 | F. Hoffmann-La Roche Ag | Pyridine-2-yl-carboxylic acid amides |
| PT2498611T (pt) | 2009-11-13 | 2018-04-13 | Celgene Int Ii Sarl | Moduladores de recetor de esfingosina 1 fosfato e métodos de síntese quiral |
| US9132136B2 (en) * | 2010-08-02 | 2015-09-15 | Hoffmann-La Roche Inc. | Pharmaceutical combination |
| JP2012106964A (ja) * | 2010-11-19 | 2012-06-07 | Ishihara Sangyo Kaisha Ltd | ２‐シクロプロピル‐６‐ハロゲノメチル‐４‐トリフルオロメチルピリジン誘導体及びその製造方法 |
| CN103415515B (zh) * | 2010-11-19 | 2015-08-26 | 因塞特公司 | 作为jak抑制剂的环丁基取代的吡咯并吡啶和吡咯并嘧啶衍生物 |
-
2013
- 2013-11-13 CA CA2885155A patent/CA2885155C/en not_active Expired - Fee Related
- 2013-11-13 CN CN201380059373.XA patent/CN104781236B/zh not_active Expired - Fee Related
- 2013-11-13 US US14/442,971 patent/US9481650B2/en not_active Expired - Fee Related
- 2013-11-13 AU AU2013346882A patent/AU2013346882B2/en not_active Ceased
- 2013-11-13 SI SI201330776T patent/SI2920150T1/sl unknown
- 2013-11-13 PL PL13792327T patent/PL2920150T3/pl unknown
- 2013-11-13 ES ES13792327.2T patent/ES2641376T3/es active Active
- 2013-11-13 KR KR1020157012637A patent/KR20150083864A/ko not_active Abandoned
- 2013-11-13 WO PCT/EP2013/073715 patent/WO2014076127A1/en not_active Ceased
- 2013-11-13 HR HRP20171346TT patent/HRP20171346T1/hr unknown
- 2013-11-13 BR BR112015010120A patent/BR112015010120A2/pt not_active Application Discontinuation
- 2013-11-13 NZ NZ70626613A patent/NZ706266A/en not_active IP Right Cessation
- 2013-11-13 MX MX2015005376A patent/MX362274B/es active IP Right Grant
- 2013-11-13 SG SG11201503573WA patent/SG11201503573WA/en unknown
- 2013-11-13 MY MYPI2015701543A patent/MY170491A/en unknown
- 2013-11-13 EP EP13792327.2A patent/EP2920150B1/en active Active
- 2013-11-13 JP JP2015542256A patent/JP6267221B2/ja not_active Expired - Fee Related
- 2013-11-13 RU RU2015119876A patent/RU2654486C2/ru active
-
2015
- 2015-03-23 IL IL237904A patent/IL237904A/en active IP Right Grant
- 2015-05-08 ZA ZA2015/03201A patent/ZA201503201B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016500060A (ja) | 2016-01-07 |
| ES2641376T3 (es) | 2017-11-08 |
| WO2014076127A1 (en) | 2014-05-22 |
| CN104781236A (zh) | 2015-07-15 |
| SI2920150T1 (sl) | 2017-10-30 |
| CN104781236B (zh) | 2018-04-24 |
| CA2885155A1 (en) | 2014-05-22 |
| HK1207377A1 (en) | 2016-01-29 |
| RU2654486C2 (ru) | 2018-05-21 |
| AU2013346882A1 (en) | 2015-04-02 |
| IL237904A (en) | 2017-10-31 |
| NZ706266A (en) | 2019-10-25 |
| AU2013346882B2 (en) | 2017-05-04 |
| CA2885155C (en) | 2021-02-16 |
| EP2920150A1 (en) | 2015-09-23 |
| HRP20171346T1 (hr) | 2017-10-20 |
| US9481650B2 (en) | 2016-11-01 |
| KR20150083864A (ko) | 2015-07-20 |
| MX2015005376A (es) | 2015-07-21 |
| EP2920150B1 (en) | 2017-07-19 |
| JP6267221B2 (ja) | 2018-01-24 |
| MY170491A (en) | 2019-08-08 |
| SG11201503573WA (en) | 2015-06-29 |
| MX362274B (es) | 2019-01-10 |
| BR112015010120A2 (pt) | 2017-07-11 |
| ZA201503201B (en) | 2016-09-28 |
| US20150291530A1 (en) | 2015-10-15 |
| RU2015119876A (ru) | 2017-01-10 |
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