PL2912162T3 - Szczepy Pichia pastoris do wytwarzania głównie homogennych struktur glikanów - Google Patents
Szczepy Pichia pastoris do wytwarzania głównie homogennych struktur glikanówInfo
- Publication number
- PL2912162T3 PL2912162T3 PL13849948T PL13849948T PL2912162T3 PL 2912162 T3 PL2912162 T3 PL 2912162T3 PL 13849948 T PL13849948 T PL 13849948T PL 13849948 T PL13849948 T PL 13849948T PL 2912162 T3 PL2912162 T3 PL 2912162T3
- Authority
- PL
- Poland
- Prior art keywords
- pichia pastoris
- glycan structure
- pastoris strains
- producing predominantly
- predominantly homogeneous
- Prior art date
Links
- 241000235058 Komagataella pastoris Species 0.000 title 1
- 150000004676 glycans Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2477—Hemicellulases not provided in a preceding group
- C12N9/2488—Mannanases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01232—Initiation-specific alpha-1,6-mannosyltransferase (2.4.1.232)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0113—Glycoprotein endo-alpha-1,2-mannosidase (3.2.1.130)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261717423P | 2012-10-23 | 2012-10-23 | |
| EP13849948.8A EP2912162B1 (en) | 2012-10-23 | 2013-10-23 | Pichia pastoris strains for producing predominantly homogeneous glycan structure |
| PCT/US2013/066335 WO2014066479A1 (en) | 2012-10-23 | 2013-10-23 | Pichia pastoris strains for producing predominantly homogeneous glycan structure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2912162T3 true PL2912162T3 (pl) | 2018-06-29 |
Family
ID=50545207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13849948T PL2912162T3 (pl) | 2012-10-23 | 2013-10-23 | Szczepy Pichia pastoris do wytwarzania głównie homogennych struktur glikanów |
Country Status (14)
| Country | Link |
|---|---|
| US (7) | US9617550B2 (pl) |
| EP (1) | EP2912162B1 (pl) |
| JP (1) | JP6407872B2 (pl) |
| KR (1) | KR102179986B1 (pl) |
| CN (2) | CN110438023A (pl) |
| AU (1) | AU2013334652B2 (pl) |
| CA (1) | CA2889202C (pl) |
| DK (1) | DK2912162T3 (pl) |
| ES (1) | ES2654664T3 (pl) |
| IL (1) | IL238401B (pl) |
| NO (1) | NO3011258T3 (pl) |
| PL (1) | PL2912162T3 (pl) |
| PT (1) | PT2912162T (pl) |
| WO (1) | WO2014066479A1 (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2912162T3 (pl) | 2012-10-23 | 2018-06-29 | Research Corporation Technologies, Inc. | Szczepy Pichia pastoris do wytwarzania głównie homogennych struktur glikanów |
| WO2015100058A1 (en) | 2013-12-23 | 2015-07-02 | Research Corporation Technologies, Inc. | Pichia pastoris surface display system |
| US11518797B2 (en) | 2014-11-11 | 2022-12-06 | Clara Foods Co. | Methods and compositions for egg white protein production |
| GB201421343D0 (en) * | 2014-12-02 | 2015-01-14 | VIB VZW and Universiteit Gent | Improved production of lipase in yeast |
| CN106191041B (zh) * | 2015-04-30 | 2020-12-29 | 杭州菁因康生物科技有限公司 | 基因打靶方法 |
| JP6912781B2 (ja) * | 2016-05-03 | 2021-08-04 | ブイアイビー ブイゼットダブリュVib Vzw | 操作された真菌宿主に由来する複合グリカンを産生するための手段および方法 |
| CN109082444A (zh) * | 2018-07-30 | 2018-12-25 | 惠州卫生职业技术学院 | 一种毕赤酵母高效基因敲除方法 |
| CN109749949A (zh) * | 2019-03-08 | 2019-05-14 | 中国人民解放军军事科学院军事医学研究院 | 一种重组酵母细胞的构建方法及其在制备低糖基化抗体中的应用 |
| US12096784B2 (en) | 2019-07-11 | 2024-09-24 | Clara Foods Co. | Protein compositions and consumable products thereof |
| BR112022000545A2 (pt) | 2019-07-11 | 2022-04-05 | Clara Foods Co | Composições de proteína e produtos de consumo destas |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| AU2022318574B2 (en) * | 2021-07-30 | 2024-03-21 | Helaina, Inc. | Methods and compositions for protein synthesis and secretion |
| WO2024032891A1 (en) * | 2022-08-11 | 2024-02-15 | Vib Vzw | Glyco-engineered yeast for therapeutic protein production |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7863020B2 (en) * | 2000-06-28 | 2011-01-04 | Glycofi, Inc. | Production of sialylated N-glycans in lower eukaryotes |
| US7029872B2 (en) | 2000-06-28 | 2006-04-18 | Glycofi, Inc | Methods for producing modified glycoproteins |
| ES2316462T3 (es) | 2000-06-30 | 2009-04-16 | Vib Vzw | Modificacion de glicosilacion de proteina en pichia pastoris. |
| US7507573B2 (en) * | 2003-11-14 | 2009-03-24 | Vib, Vzw | Modification of protein glycosylation in methylotrophic yeast |
| US20110092374A1 (en) | 2009-10-16 | 2011-04-21 | Vib, Vzw | Methods for producing substantially homogeneous hybrid or complex n-glycans in methylotrophic yeasts |
| US9187552B2 (en) * | 2010-05-27 | 2015-11-17 | Merck Sharp & Dohme Corp. | Method for preparing antibodies having improved properties |
| PL2912162T3 (pl) | 2012-10-23 | 2018-06-29 | Research Corporation Technologies, Inc. | Szczepy Pichia pastoris do wytwarzania głównie homogennych struktur glikanów |
-
2013
- 2013-10-23 PL PL13849948T patent/PL2912162T3/pl unknown
- 2013-10-23 CN CN201910719202.4A patent/CN110438023A/zh active Pending
- 2013-10-23 CN CN201380055395.9A patent/CN104797703A/zh active Pending
- 2013-10-23 JP JP2015539748A patent/JP6407872B2/ja active Active
- 2013-10-23 EP EP13849948.8A patent/EP2912162B1/en active Active
- 2013-10-23 KR KR1020157010911A patent/KR102179986B1/ko active Active
- 2013-10-23 AU AU2013334652A patent/AU2013334652B2/en active Active
- 2013-10-23 PT PT138499488T patent/PT2912162T/pt unknown
- 2013-10-23 US US14/437,683 patent/US9617550B2/en active Active
- 2013-10-23 CA CA2889202A patent/CA2889202C/en active Active
- 2013-10-23 DK DK13849948.8T patent/DK2912162T3/en active
- 2013-10-23 ES ES13849948.8T patent/ES2654664T3/es active Active
- 2013-10-23 WO PCT/US2013/066335 patent/WO2014066479A1/en not_active Ceased
-
2014
- 2014-05-27 NO NO14726376A patent/NO3011258T3/no unknown
-
2015
- 2015-04-21 IL IL238401A patent/IL238401B/en active IP Right Grant
-
2017
- 2017-02-28 US US15/444,870 patent/US10329572B2/en active Active
-
2019
- 2019-05-07 US US16/404,838 patent/US10612033B2/en active Active
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2020
- 2020-02-26 US US16/801,466 patent/US11220692B2/en active Active
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2021
- 2021-11-17 US US17/528,619 patent/US11866715B2/en active Active
-
2023
- 2023-11-28 US US18/520,960 patent/US12359211B2/en active Active
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2025
- 2025-06-10 US US19/232,956 patent/US20250304980A1/en active Pending
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