[go: up one dir, main page]

PL2944690T3 - Nowe fukozylotransferazy i ich zastosowanie - Google Patents

Nowe fukozylotransferazy i ich zastosowanie

Info

Publication number
PL2944690T3
PL2944690T3 PL15169876T PL15169876T PL2944690T3 PL 2944690 T3 PL2944690 T3 PL 2944690T3 PL 15169876 T PL15169876 T PL 15169876T PL 15169876 T PL15169876 T PL 15169876T PL 2944690 T3 PL2944690 T3 PL 2944690T3
Authority
PL
Poland
Prior art keywords
applications
fucosyltransferases
novel
novel fucosyltransferases
Prior art date
Application number
PL15169876T
Other languages
English (en)
Inventor
Julia Parkot
Eric HÜFNER
Stefan Jennewein
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of PL2944690T3 publication Critical patent/PL2944690T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/01214Glycoprotein 3-alpha-L-fucosyltransferase (2.4.1.214)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL15169876T 2010-10-11 2010-10-11 Nowe fukozylotransferazy i ich zastosowanie PL2944690T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10187167.1A EP2439264B1 (en) 2010-10-11 2010-10-11 Novel fucosyltransferases and their applications
EP15169876.8A EP2944690B1 (en) 2010-10-11 2010-10-11 Novel fucosyltransferases and their applications

Publications (1)

Publication Number Publication Date
PL2944690T3 true PL2944690T3 (pl) 2018-05-30

Family

ID=43244921

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15169876T PL2944690T3 (pl) 2010-10-11 2010-10-11 Nowe fukozylotransferazy i ich zastosowanie

Country Status (16)

Country Link
US (1) US9441211B2 (pl)
EP (2) EP2439264B1 (pl)
JP (1) JP6097691B2 (pl)
CN (1) CN103201380B (pl)
AU (1) AU2011315656B2 (pl)
BR (1) BR112013008822A8 (pl)
DK (2) DK2439264T3 (pl)
ES (1) ES2663627T3 (pl)
MX (1) MX344691B (pl)
MY (1) MY189569A (pl)
NZ (1) NZ609127A (pl)
PH (1) PH12013500684B1 (pl)
PL (1) PL2944690T3 (pl)
RU (1) RU2642307C2 (pl)
SG (1) SG189300A1 (pl)
WO (1) WO2012049083A2 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014DN07752A (pl) 2012-02-29 2015-05-15 Ethicon Endo Surgery Inc
EP3572520A1 (en) 2013-09-10 2019-11-27 Jennewein Biotechnologie GmbH Production of oligosaccharides
DK2896628T3 (en) 2014-01-20 2019-01-14 Jennewein Biotechnologie Gmbh Process for Effective Purification of Neutral Milk Oligosaccharides (HMOs) from Microbial Fermentation
ES2715010T3 (es) 2014-03-31 2019-05-31 Jennewein Biotechnologie Gmbh Fermentación total de oligosacáridos
KR101718681B1 (ko) 2014-06-23 2017-03-22 서울대학교산학협력단 가용성 단백질 발현량 및 활성이 증대된 헬리코박터 파일로리 유래 α-1,3 푸코실 전달효소의 유전자와 단백질 및 α-1,3 푸코실올리고당 생산에의 응용
EP3191499A4 (en) * 2014-09-09 2018-06-06 Glycosyn LLC Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
SG10201903823QA (en) 2014-10-31 2019-05-30 Whole Biome Inc Methods and compositions relating to microbial treatment and diagnosis of disorders
EP3050973A1 (en) * 2015-01-30 2016-08-03 Jennewein Biotechnologie GmbH Fermentation process for producing monosaccharides in free form from nucleotide-activated sugars
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR101794971B1 (ko) * 2016-02-02 2017-11-08 서울대학교 산학협력단 α-1,3-푸코실락토오즈의 대량 생산 방법
CN105695537B (zh) * 2016-02-29 2019-11-19 福建农林大学 一种降血糖及调节肠道菌群的糖基化浒苔寡糖制备方法
EP3315610B1 (en) 2016-10-29 2020-12-16 Jennewein Biotechnologie GmbH Process for the production of fucosylated oligosaccharides
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN106434591A (zh) * 2016-12-13 2017-02-22 福建农林大学 一种岩藻糖基转移酶及其应用
CN106434590A (zh) * 2016-12-13 2017-02-22 福建农林大学 一种岩藻糖基转移酶及其基因工程菌和应用
KR101794972B1 (ko) * 2017-01-26 2017-11-08 서울대학교 산학협력단 α-1,3-푸코실락토오즈의 대량 생산 방법
EP3613858B1 (en) * 2017-04-21 2024-03-13 Seoul National University R&DB Foundation Method for producing 3'-fucosyllactose using corynebacterium glutamicum
EP3425052A1 (en) 2017-07-07 2019-01-09 Jennewein Biotechnologie GmbH Fucosyltransferases and their use in producing fucosylated oligosaccharides
WO2019046646A1 (en) 2017-08-30 2019-03-07 Whole Biome Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS
WO2019106620A1 (en) * 2017-11-30 2019-06-06 Glycom A/S Human milk oligosaccharides and synthetic compositions thereof for microbiota modulation
CN113164526A (zh) 2018-07-19 2021-07-23 潘德勒姆治疗公司 用于微生物植入的方法和组合物
WO2020127417A2 (en) 2018-12-18 2020-06-25 Inbiose N.V. PRODUCTION OF 3-FUCOSYLLACTOSE AND LACTOSE CONVERTING α-1,3-FUCOSYLTRANSFERASE ENZYMES
EP3751003A1 (en) 2019-06-12 2020-12-16 Jennewein Biotechnologie GmbH Production of fucosylated oligosaccharides in bacillus
US20240301456A1 (en) * 2021-02-08 2024-09-12 Kyowa Hakko Bio Co., Ltd. Protein having 1,3-fucosyltransferase activity, and method for producing fucose-containing sugar
CN115058465B (zh) * 2022-06-30 2025-03-07 山东大学 一种岩藻糖基化软骨素及其制备方法和应用
DK181911B1 (en) * 2022-07-15 2025-03-18 Dsm Ip Assets Bv GENETICALLY ENGINEERED CELLS COMPRISING A RECOMBINANT NUCLEIC ACID SEQUNCE ENCODING A FUCOSYLTRANSFERASE FOR IN VIVO SYNTHESIS OF COMPLEX FUCOSYLATED HUMAN MILK OLIGOSACCHARIDES (HMOs) AND METHODS FOR PRODUCING THE HMOs AND USE OF THE ENZYME
CN117187206B (zh) * 2023-05-19 2024-06-18 无锡特殊食品与营养健康研究院有限公司 肠道微生物来源的岩藻糖基转移酶及其应用
DK202330269A1 (en) * 2023-10-17 2025-06-16 Dsm Ip Assets Bv New fucosyltransferases for in vivo synthesis of complex fucosylated human milk oligosaccharides mixtures comprising lnfp-vi or lnfp-v

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2125092C1 (ru) * 1991-10-15 1999-01-20 Дзе Скриппс Рисерч Инститьют Способ получения фукозилированного углевода, способ получения фукозилированной сиалилированной углеводной молекулы, реакционная система in vitro
EP0621337A1 (en) * 1993-01-25 1994-10-26 American Cyanamid Company Codon optimized DNA sequence for insect toxin AaIT
US5728554A (en) * 1995-04-11 1998-03-17 Cytel Corporation Enzymatic synthesis of glycosidic linkages
US5922577A (en) * 1995-04-11 1999-07-13 Cytel Corporation Enzymatic synthesis of glycosidic linkages
WO1998055630A2 (en) 1997-06-06 1998-12-10 The Governors Of The University Of Alberta Alpha-1,3-fucosyltransferase of helicobacter pylori
US6500661B1 (en) * 1998-01-15 2002-12-31 Neose Technologies, Inc. Enzymatic conversion of GDP-mannose to GDP-fucose
AT408446B (de) 1999-02-18 2001-11-26 Altmann Friedrich Dr Fucosyltransferase-gen
FI19992070A7 (fi) * 1999-09-28 2001-03-29 Carbion Oy Uudet fukosyloidut oligosakkaridit ja menetelmä niiden valmistamiseksi
TWI237527B (en) 2001-11-06 2005-08-01 Delta Optoelectronics Inc Driver apparatus for a flat-type lamp and driving method for the same
US7326770B2 (en) 2004-01-22 2008-02-05 Neose Technologies, Inc. H. pylori fucosyltransferases
US7642072B2 (en) * 2004-07-26 2010-01-05 Enzon Pharmaceuticals, Inc. Optimized interferon-beta gene
JP5709356B2 (ja) * 2006-01-13 2015-04-30 アメリカ合衆国 哺乳動物細胞における発現のためのコドン最適化IL−15およびIL−15R−α遺伝子
WO2008143713A2 (en) 2006-12-22 2008-11-27 Dow Agrosciences Llc Plant-made west nile virus (wnv) vaccines, vectors and plant codon optimized sequences
JP2009095264A (ja) * 2007-10-15 2009-05-07 Univ Of Ryukyus コドン最適化ロイヤリシン遺伝子
NZ593448A (en) * 2008-12-19 2012-06-29 Jennewein Biotechnologie Gmbh Synthesis of fucosylated compounds

Also Published As

Publication number Publication date
EP2944690A3 (en) 2016-03-09
SG189300A1 (en) 2013-05-31
RU2642307C2 (ru) 2018-01-24
PH12013500684B1 (en) 2017-10-13
DK2439264T3 (en) 2015-08-03
EP2944690B1 (en) 2017-12-20
MY189569A (en) 2022-02-17
US9441211B2 (en) 2016-09-13
EP2944690A2 (en) 2015-11-18
BR112013008822A2 (pt) 2017-09-19
PH12013500684A1 (en) 2013-05-06
DK2944690T3 (en) 2018-04-03
MX2013004055A (es) 2013-06-05
WO2012049083A2 (en) 2012-04-19
JP2013541952A (ja) 2013-11-21
NZ609127A (en) 2014-10-31
CN103201380A (zh) 2013-07-10
RU2013120902A (ru) 2014-11-20
EP2439264A1 (en) 2012-04-11
US20130217068A1 (en) 2013-08-22
ES2663627T3 (es) 2018-04-16
MX344691B (es) 2016-12-29
BR112013008822A8 (pt) 2023-01-31
CN103201380B (zh) 2018-07-24
JP6097691B2 (ja) 2017-03-15
EP2439264B1 (en) 2015-06-03
AU2011315656B2 (en) 2016-01-21
WO2012049083A3 (en) 2012-06-14
AU2011315656A1 (en) 2013-05-02

Similar Documents

Publication Publication Date Title
PH12013500684A1 (en) Novel fucosyltransferases and their applications
IL249669B (en) Converted 5-fluoro-h1-pyrazolopyridines and their use
IL226904A (en) Inganol-3-acetylates iii and Inganol-3-carbamates
IL221511A (en) Arilatriazolones associated with bis aryl and their use
IL233051B (en) Anti-phf-tau antibodies and uses thereof
ZA201208173B (en) Peptices and their use
ZA201209259B (en) Uses and compositions
GB201007384D0 (en) Enzymes
IL229844B (en) Anti-psgl-1 antibodies and their use
SG10201500041XA (en) Superhydrophilic and water-capturing surfaces
LT2531518T (lt) Oligopeptidiniai dariniai ir jų panaudojimas
PT2601251E (pt) Filossilicato modificado
GB201007196D0 (en) Gas-to-liquid technology
SI2552440T1 (sl) Nove kombinacije in uporaba
GB201007202D0 (en) Product and uses
GB201017820D0 (en) Cells and devices
SG10201508549UA (en) Modified tamavidin
EP2638160B8 (en) Nuclions and ribocapsids
GB201016269D0 (en) Curable polymers and their uses
GB201102999D0 (en) External damper
GB201014319D0 (en) Compounds and uses thereof
GB201015848D0 (en) Glycobiological surfaces
GB201019361D0 (en) Biosensor and uses thereof
GB201002164D0 (en) Concept four
GB201020268D0 (en) Composition and uses