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PL2943493T3 - Związki terapeutyczne do leczenia zakażeń wirusowych - Google Patents

Związki terapeutyczne do leczenia zakażeń wirusowych

Info

Publication number
PL2943493T3
PL2943493T3 PL14701647T PL14701647T PL2943493T3 PL 2943493 T3 PL2943493 T3 PL 2943493T3 PL 14701647 T PL14701647 T PL 14701647T PL 14701647 T PL14701647 T PL 14701647T PL 2943493 T3 PL2943493 T3 PL 2943493T3
Authority
PL
Poland
Prior art keywords
treatment
viral infections
therapeutic compounds
therapeutic
compounds
Prior art date
Application number
PL14701647T
Other languages
English (en)
Inventor
Steven S. Bondy
Carina E. Cannizzaro
Chien-Hung Chou
Yunfeng Eric Hu
John O. Link
Qi Liu
Scott D. Schroeder
Winston C. Tse
Jennifer R. Zhang
Original Assignee
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Publication of PL2943493T3 publication Critical patent/PL2943493T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL14701647T 2013-01-09 2014-01-09 Związki terapeutyczne do leczenia zakażeń wirusowych PL2943493T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361750759P 2013-01-09 2013-01-09
PCT/US2014/010937 WO2014110296A1 (en) 2013-01-09 2014-01-09 Therapeutic compounds for the treatment of viral infections
EP14701647.1A EP2943493B1 (en) 2013-01-09 2014-01-09 Therapeutic compounds for the treatment of viral infections

Publications (1)

Publication Number Publication Date
PL2943493T3 true PL2943493T3 (pl) 2017-12-29

Family

ID=50023885

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14701647T PL2943493T3 (pl) 2013-01-09 2014-01-09 Związki terapeutyczne do leczenia zakażeń wirusowych

Country Status (11)

Country Link
US (1) US9012441B2 (pl)
EP (1) EP2943493B1 (pl)
JP (1) JP5860197B1 (pl)
AU (1) AU2014205315B2 (pl)
CA (1) CA2897268C (pl)
ES (1) ES2642265T3 (pl)
NZ (2) NZ727792A (pl)
PL (1) PL2943493T3 (pl)
PT (1) PT2943493T (pl)
SI (1) SI2943493T1 (pl)
WO (1) WO2014110296A1 (pl)

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JP5941598B2 (ja) 2013-01-09 2016-06-29 ギリアード サイエンシーズ, インコーポレイテッド 5員ヘテロアリールおよびそれらの抗ウイルス剤としての使用
TWI694071B (zh) 2013-03-01 2020-05-21 美商基利科學股份有限公司 治療反轉錄病毒科(Retroviridae)病毒感染之治療性化合物
US10202353B2 (en) 2014-02-28 2019-02-12 Gilead Sciences, Inc. Therapeutic compounds
PT3186239T (pt) 2014-08-29 2019-01-10 Gilead Sciences Inc Agentes antirretrovirais
SG11201705069YA (en) 2014-12-26 2017-07-28 Univ Emory N4-hydroxycytidine and derivatives and anti-viral uses related thereto
JP6716785B2 (ja) 2016-08-19 2020-07-01 ギリアード サイエンシーズ, インコーポレイテッド Hivウイルス感染症の予防的または治療的処置に有用な治療用化合物
TW201906834A (zh) 2017-05-02 2019-02-16 英商Viiv醫療保健英國(No.5)有限公司 人類免疫不全病毒複製之抑制劑
AR112412A1 (es) 2017-08-17 2019-10-23 Gilead Sciences Inc Formas de sal de colina de un inhibidor de la cápside del vih
TWI687415B (zh) 2017-08-17 2020-03-11 美商基利科學股份有限公司 Hiv蛋白質膜抑制劑之固體形式
PL3706762T3 (pl) 2017-12-07 2025-02-10 Emory University N4-hydroksycytydyna i pochodne oraz związane z nimi zastosowania przeciwwirusowe
ES2958828T3 (es) 2018-02-15 2024-02-15 Gilead Sciences Inc Derivados de piridina y su uso para tratar una infección por VIH
PL3752496T3 (pl) 2018-02-16 2023-11-27 Gilead Sciences, Inc. Sposoby i związki pośrednie do wytwarzania związku terapeutycznego przydatnego w leczeniu infekcji wirusowej retroviridae
WO2019198024A1 (en) 2018-04-11 2019-10-17 VIIV Healthcare UK (No.5) Limited 4-oxo-3,4-dihydroquinazoline compounds as inhibitors of human immunodeficiency virus replication
CN120078775A (zh) 2018-07-16 2025-06-03 吉利德科学公司 用于治疗hiv的衣壳抑制剂
BR112021001617A2 (pt) 2018-08-09 2021-04-27 VIIV Healthcare UK (No.5) Limited inibidores de replicação do vírus da imunodeficiência humana
WO2020053811A1 (en) 2018-09-14 2020-03-19 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
WO2020058844A1 (en) 2018-09-20 2020-03-26 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
PE20211781A1 (es) 2018-10-24 2021-09-08 Viiv Healthcare Uk No 5 Ltd Inhibidores de la replicacion del virus de la inmunodeficiencia humana
EP3870576B1 (en) 2018-10-24 2024-01-24 VIIV Healthcare UK (No.5) Limited Bezopyrazole derivatives as inhibitors of human immunodeficiency virus replication
JP7500555B2 (ja) 2018-10-25 2024-06-17 ヴィーブ ヘルスケア ユーケー(ナンバー5)リミテッド ヒト免疫不全ウイルス複製の阻害剤
ES2969030T3 (es) 2018-10-29 2024-05-16 Viiv Healthcare Uk No 5 Ltd Derivados de quinazolinil-indazol y su uso como inhibidores de replicación de virus de inmunodeficiencia humana
EP3877387A1 (en) 2018-11-05 2021-09-15 ViiV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
WO2020095176A1 (en) 2018-11-05 2020-05-14 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
US20230069963A1 (en) * 2018-12-27 2023-03-09 Taisho Pharmaceutical Co., Ltd. Pyrazolo[1,5-a]pyrimidine macrocyclic compound
UY38559A (es) 2019-02-01 2020-07-31 Viiv Healthcare Uk No 5 Ltd Inhibidores de la replicación del virus de la inmunodeficiencia humana
WO2020222108A1 (en) 2019-04-30 2020-11-05 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
AR119174A1 (es) 2019-06-19 2021-12-01 Viiv Healthcare Uk No 5 Ltd Inhibidores de la replicación del virus de inmunodeficiencia humana
US20220409619A1 (en) 2019-10-01 2022-12-29 Viiv Healthcare Uk (No. 5) Limited Inhibitors of human immunodeficiency virus replication
JP2022551254A (ja) 2019-10-01 2022-12-08 ビーブ、ヘルスケア、ユーケー、(ナンバー5)、リミテッド ヒト免疫不全ウイルスの複製阻害剤
TW202128648A (zh) 2019-10-04 2021-08-01 英商Viiv醫療保健英國(No 5)有限公司 人類免疫不全病毒複製之抑制劑
EP4041729B1 (en) 2019-10-08 2023-09-27 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
AU2020391466B2 (en) 2019-11-26 2024-05-23 Gilead Sciences, Inc. Capsid inhibitors for the prevention of HIV
EP4066839A4 (en) 2019-11-28 2023-12-27 Shionogi & Co., Ltd PROPHYLACTIC AND THERAPEUTIC MEDICINAL PRODUCT FOR HIV INFECTIOUS DISEASES, CHARACTERIZED BY CONTAINING THE COMBINATION OF INTEGRAS INHIBITORS AND ANTI-HIV AGENTS
CA3170536A1 (en) 2020-03-06 2021-09-10 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
WO2021176367A1 (en) 2020-03-06 2021-09-10 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
AU2021256166B2 (en) 2020-04-15 2024-05-23 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
CA3181690A1 (en) 2020-06-25 2021-12-30 Chienhung CHOU Capsid inhibitors for the treatment of hiv
WO2023102529A1 (en) 2021-12-03 2023-06-08 Gilead Sciences, Inc. Therapeutic compounds for hiv virus infection
PL4445900T3 (pl) 2021-12-03 2025-09-22 Gilead Sciences, Inc. Związki terapeutyczne przeciwko zakażeniu wirusem hiv
WO2023102523A1 (en) 2021-12-03 2023-06-08 Gilead Sciences, Inc. Therapeutic compounds for hiv virus infection
AR132951A1 (es) 2023-06-15 2025-08-13 Viiv Healthcare Uk No 5 Ltd Métodos e intermedios para preparar compuestos
WO2025169059A1 (en) 2024-02-05 2025-08-14 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication

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JP5465667B2 (ja) * 2007-06-29 2014-04-09 ギリアード サイエンシーズ, インコーポレイテッド 抗ウイルス化合物
US8927569B2 (en) * 2007-07-19 2015-01-06 Merck Sharp & Dohme Corp. Macrocyclic compounds as antiviral agents
WO2009062285A1 (en) 2007-11-16 2009-05-22 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
US8338441B2 (en) 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
US20130165489A1 (en) 2010-05-03 2013-06-27 The Trustees Of The University Of Pennsylvania Small Molecule Modulators of HIV-1 Capsid Stability and Methods Thereof
MA34397B1 (fr) 2010-07-02 2013-07-03 Gilead Sciences Inc Dérivés d'acide napht-2-ylacétique dans le traitement du sida
WO2012003498A1 (en) 2010-07-02 2012-01-05 Gilead Sciences, Inc. 2 -quinolinyl- acetic acid derivatives as hiv antiviral compounds
WO2012145728A1 (en) 2011-04-21 2012-10-26 Gilead Sciences, Inc. Benzothiazole compounds and their pharmaceutical use
PT2729448E (pt) 2011-07-06 2015-12-02 Gilead Sciences Inc Compostos para o tratamento de vih
CN102863512B (zh) 2011-07-07 2016-04-20 上海泓博智源医药技术有限公司 抗病毒化合物
EP3070081B1 (en) 2012-04-20 2018-02-28 Gilead Sciences, Inc. Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection
GB201213087D0 (en) 2012-07-24 2012-09-05 Medical Res Council Inhibition of HIV-1 infection
TW201443037A (zh) 2013-01-09 2014-11-16 Gilead Sciences Inc 治療用化合物
JP5941598B2 (ja) 2013-01-09 2016-06-29 ギリアード サイエンシーズ, インコーポレイテッド 5員ヘテロアリールおよびそれらの抗ウイルス剤としての使用

Also Published As

Publication number Publication date
EP2943493B1 (en) 2017-08-02
ES2642265T3 (es) 2017-11-16
US20140221417A1 (en) 2014-08-07
HK1216421A1 (en) 2016-11-11
JP5860197B1 (ja) 2016-02-16
US9012441B2 (en) 2015-04-21
EP2943493A1 (en) 2015-11-18
AU2014205315B2 (en) 2016-11-17
NZ727792A (en) 2018-04-27
CA2897268C (en) 2018-12-04
WO2014110296A1 (en) 2014-07-17
SI2943493T1 (sl) 2017-11-30
NZ631726A (en) 2017-01-27
JP2016508150A (ja) 2016-03-17
CA2897268A1 (en) 2014-07-17
AU2014205315A1 (en) 2015-07-16
PT2943493T (pt) 2017-10-23

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