PL2861560T3 - Sole saksagliptyny z kwasami organicznymi - Google Patents
Sole saksagliptyny z kwasami organicznymiInfo
- Publication number
- PL2861560T3 PL2861560T3 PL13731869T PL13731869T PL2861560T3 PL 2861560 T3 PL2861560 T3 PL 2861560T3 PL 13731869 T PL13731869 T PL 13731869T PL 13731869 T PL13731869 T PL 13731869T PL 2861560 T3 PL2861560 T3 PL 2861560T3
- Authority
- PL
- Poland
- Prior art keywords
- saxagliptin
- salts
- organic acids
- acids
- organic
- Prior art date
Links
- 150000007524 organic acids Chemical class 0.000 title 1
- 235000005985 organic acids Nutrition 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- QGJUIPDUBHWZPV-SGTAVMJGSA-N saxagliptin Chemical class C1C(C2)CC(C3)CC2(O)CC13[C@H](N)C(=O)N1[C@H](C#N)C[C@@H]2C[C@@H]21 QGJUIPDUBHWZPV-SGTAVMJGSA-N 0.000 title 1
- 229960004937 saxagliptin Drugs 0.000 title 1
- 108010033693 saxagliptin Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
- C07C65/05—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1572MU2012 | 2012-05-24 | ||
| US201261668537P | 2012-07-06 | 2012-07-06 | |
| PCT/IB2013/001031 WO2013175297A1 (en) | 2012-05-24 | 2013-05-24 | Salts of saxagliptin with organic acids |
| EP13731869.7A EP2861560B1 (en) | 2012-05-24 | 2013-05-24 | Salts of saxagliptin with organic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2861560T3 true PL2861560T3 (pl) | 2019-01-31 |
Family
ID=49623232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13731869T PL2861560T3 (pl) | 2012-05-24 | 2013-05-24 | Sole saksagliptyny z kwasami organicznymi |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9994523B2 (pl) |
| EP (1) | EP2861560B1 (pl) |
| AU (1) | AU2013264925B2 (pl) |
| CA (1) | CA2885957C (pl) |
| ES (1) | ES2690321T3 (pl) |
| PL (1) | PL2861560T3 (pl) |
| WO (1) | WO2013175297A1 (pl) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6395767B2 (en) | 2000-03-10 | 2002-05-28 | Bristol-Myers Squibb Company | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method |
| US7420079B2 (en) | 2002-12-09 | 2008-09-02 | Bristol-Myers Squibb Company | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof |
| US7214702B2 (en) | 2004-05-25 | 2007-05-08 | Bristol-Myers Squibb Company | Process for producing a dipeptidyl peptidase IV inhibitor |
| RU2008107873A (ru) * | 2005-08-04 | 2009-09-10 | Новартис АГ (CH) | Новые соединения |
| PE20090696A1 (es) | 2007-04-20 | 2009-06-20 | Bristol Myers Squibb Co | Formas cristalinas de saxagliptina y procesos para preparar las mismas |
| JP2012509277A (ja) | 2008-11-19 | 2012-04-19 | オースペックス・ファーマシューティカルズ・インコーポレイテッド | ジペプチジルペプチダーゼivのヒドロキシアダマンチル阻害剤 |
| CN102459170B (zh) | 2009-04-09 | 2014-07-23 | 桑多斯股份公司 | 沙格列汀的结晶形式 |
| WO2011140328A1 (en) | 2010-05-05 | 2011-11-10 | Teva Pharmaceutical Industries Ltd. | Saxagliptin intermediates, saxagliptin polymorphs, and processes for preparation thereof |
| EP2601175A1 (en) | 2010-08-06 | 2013-06-12 | Sandoz AG | A novel crystalline compound comprising saxagliptin and phosphoric acid |
| WO2012017029A1 (en) | 2010-08-06 | 2012-02-09 | Sandoz Ag | Novel salts of saxagrliptin with organic di-acids |
| CN102086172A (zh) | 2011-01-13 | 2011-06-08 | 廖国超 | 沙格列汀的药用盐及其制备方法 |
| WO2013160354A1 (en) | 2012-04-25 | 2013-10-31 | Enantia, S.L. | Crystalline forms of saxagliptin |
| WO2014002114A2 (en) | 2012-06-29 | 2014-01-03 | Glenmark Pharmaceuticals Limited; Glenmark Generics Limited | Process for the preparation of saxagliptin and hydrates thereof |
| EP2867206A2 (en) | 2012-07-02 | 2015-05-06 | Ranbaxy Laboratories Limited | Saxagliptin salts |
-
2013
- 2013-05-24 ES ES13731869.7T patent/ES2690321T3/es active Active
- 2013-05-24 WO PCT/IB2013/001031 patent/WO2013175297A1/en not_active Ceased
- 2013-05-24 CA CA2885957A patent/CA2885957C/en active Active
- 2013-05-24 EP EP13731869.7A patent/EP2861560B1/en not_active Not-in-force
- 2013-05-24 PL PL13731869T patent/PL2861560T3/pl unknown
- 2013-05-24 AU AU2013264925A patent/AU2013264925B2/en not_active Ceased
- 2013-05-24 US US14/403,552 patent/US9994523B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9994523B2 (en) | 2018-06-12 |
| AU2013264925B2 (en) | 2017-08-17 |
| CA2885957A1 (en) | 2013-11-28 |
| ES2690321T3 (es) | 2018-11-20 |
| EP2861560A1 (en) | 2015-04-22 |
| AU2013264925A1 (en) | 2014-12-18 |
| EP2861560B1 (en) | 2018-08-08 |
| US20150353490A1 (en) | 2015-12-10 |
| WO2013175297A1 (en) | 2013-11-28 |
| CA2885957C (en) | 2019-10-22 |
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