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PL2861560T3 - Sole saksagliptyny z kwasami organicznymi - Google Patents

Sole saksagliptyny z kwasami organicznymi

Info

Publication number
PL2861560T3
PL2861560T3 PL13731869T PL13731869T PL2861560T3 PL 2861560 T3 PL2861560 T3 PL 2861560T3 PL 13731869 T PL13731869 T PL 13731869T PL 13731869 T PL13731869 T PL 13731869T PL 2861560 T3 PL2861560 T3 PL 2861560T3
Authority
PL
Poland
Prior art keywords
saxagliptin
salts
organic acids
acids
organic
Prior art date
Application number
PL13731869T
Other languages
English (en)
Inventor
Padiyath Mohammed AKBARALI
Venkata Ramana KINTALI
Shreenivasa Murthy H N
Prakash Bhaskar SHETTY
Narendra Manjeshwar MALLYA
Venkataramana Lachhi REDDY
Original Assignee
Apotex Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apotex Inc. filed Critical Apotex Inc.
Publication of PL2861560T3 publication Critical patent/PL2861560T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C07C65/05Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL13731869T 2012-05-24 2013-05-24 Sole saksagliptyny z kwasami organicznymi PL2861560T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1572MU2012 2012-05-24
US201261668537P 2012-07-06 2012-07-06
PCT/IB2013/001031 WO2013175297A1 (en) 2012-05-24 2013-05-24 Salts of saxagliptin with organic acids
EP13731869.7A EP2861560B1 (en) 2012-05-24 2013-05-24 Salts of saxagliptin with organic acids

Publications (1)

Publication Number Publication Date
PL2861560T3 true PL2861560T3 (pl) 2019-01-31

Family

ID=49623232

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13731869T PL2861560T3 (pl) 2012-05-24 2013-05-24 Sole saksagliptyny z kwasami organicznymi

Country Status (7)

Country Link
US (1) US9994523B2 (pl)
EP (1) EP2861560B1 (pl)
AU (1) AU2013264925B2 (pl)
CA (1) CA2885957C (pl)
ES (1) ES2690321T3 (pl)
PL (1) PL2861560T3 (pl)
WO (1) WO2013175297A1 (pl)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395767B2 (en) 2000-03-10 2002-05-28 Bristol-Myers Squibb Company Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
US7420079B2 (en) 2002-12-09 2008-09-02 Bristol-Myers Squibb Company Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof
US7214702B2 (en) 2004-05-25 2007-05-08 Bristol-Myers Squibb Company Process for producing a dipeptidyl peptidase IV inhibitor
RU2008107873A (ru) * 2005-08-04 2009-09-10 Новартис АГ (CH) Новые соединения
PE20090696A1 (es) 2007-04-20 2009-06-20 Bristol Myers Squibb Co Formas cristalinas de saxagliptina y procesos para preparar las mismas
JP2012509277A (ja) 2008-11-19 2012-04-19 オースペックス・ファーマシューティカルズ・インコーポレイテッド ジペプチジルペプチダーゼivのヒドロキシアダマンチル阻害剤
CN102459170B (zh) 2009-04-09 2014-07-23 桑多斯股份公司 沙格列汀的结晶形式
WO2011140328A1 (en) 2010-05-05 2011-11-10 Teva Pharmaceutical Industries Ltd. Saxagliptin intermediates, saxagliptin polymorphs, and processes for preparation thereof
EP2601175A1 (en) 2010-08-06 2013-06-12 Sandoz AG A novel crystalline compound comprising saxagliptin and phosphoric acid
WO2012017029A1 (en) 2010-08-06 2012-02-09 Sandoz Ag Novel salts of saxagrliptin with organic di-acids
CN102086172A (zh) 2011-01-13 2011-06-08 廖国超 沙格列汀的药用盐及其制备方法
WO2013160354A1 (en) 2012-04-25 2013-10-31 Enantia, S.L. Crystalline forms of saxagliptin
WO2014002114A2 (en) 2012-06-29 2014-01-03 Glenmark Pharmaceuticals Limited; Glenmark Generics Limited Process for the preparation of saxagliptin and hydrates thereof
EP2867206A2 (en) 2012-07-02 2015-05-06 Ranbaxy Laboratories Limited Saxagliptin salts

Also Published As

Publication number Publication date
US9994523B2 (en) 2018-06-12
AU2013264925B2 (en) 2017-08-17
CA2885957A1 (en) 2013-11-28
ES2690321T3 (es) 2018-11-20
EP2861560A1 (en) 2015-04-22
AU2013264925A1 (en) 2014-12-18
EP2861560B1 (en) 2018-08-08
US20150353490A1 (en) 2015-12-10
WO2013175297A1 (en) 2013-11-28
CA2885957C (en) 2019-10-22

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