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PL2622078T3 - Białko fuzyjne dla ekspresji białka wydzielniczego - Google Patents

Białko fuzyjne dla ekspresji białka wydzielniczego

Info

Publication number
PL2622078T3
PL2622078T3 PL11763647T PL11763647T PL2622078T3 PL 2622078 T3 PL2622078 T3 PL 2622078T3 PL 11763647 T PL11763647 T PL 11763647T PL 11763647 T PL11763647 T PL 11763647T PL 2622078 T3 PL2622078 T3 PL 2622078T3
Authority
PL
Poland
Prior art keywords
protein
secretory
expression
fusion protein
fusion
Prior art date
Application number
PL11763647T
Other languages
English (en)
Inventor
Joen Luirink
Wouter S P Jong
Original Assignee
Abera Bioscience Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abera Bioscience Ab filed Critical Abera Bioscience Ab
Publication of PL2622078T3 publication Critical patent/PL2622078T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL11763647T 2010-09-28 2011-09-28 Białko fuzyjne dla ekspresji białka wydzielniczego PL2622078T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1051000 2010-09-28
PCT/EP2011/066854 WO2012041899A1 (en) 2010-09-28 2011-09-28 Fusion protein for secretory protein expression
EP11763647.2A EP2622078B1 (en) 2010-09-28 2011-09-28 Fusion protein for secretory protein expression

Publications (1)

Publication Number Publication Date
PL2622078T3 true PL2622078T3 (pl) 2015-05-29

Family

ID=44719941

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11763647T PL2622078T3 (pl) 2010-09-28 2011-09-28 Białko fuzyjne dla ekspresji białka wydzielniczego

Country Status (7)

Country Link
US (1) US9322011B2 (pl)
EP (1) EP2622078B1 (pl)
CN (1) CN103228787B (pl)
CA (1) CA2811699C (pl)
ES (1) ES2529442T3 (pl)
PL (1) PL2622078T3 (pl)
WO (1) WO2012041899A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201009861D0 (en) * 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
EP2833911A4 (en) 2012-04-06 2016-07-13 Univ Cornell SUB-VACCINE VACCINATING PLATFORM FOR ROBUST HUMORAL AND CELLULAR IMMUNE RESPONSES
US10357555B2 (en) * 2012-07-10 2019-07-23 Transgene Sa Mycobacterial antigen vaccine
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
BR112017025954A2 (pt) * 2015-06-02 2018-08-14 De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport apresentação em superfície de antígenos em vesículas de membrana externa gram-negativa
EP4524157A3 (en) 2017-10-25 2025-06-18 Abera Bioscience AB Omv display
GB202009411D0 (en) * 2020-06-19 2020-08-05 Prokarium Ltd Autotransporter systems
EP3981879A1 (en) * 2020-10-09 2022-04-13 Stada Arzneimittel Ag Method of producing a recombinant protein in a host cell which has a disabled rhamnose metabolism as well as expression vectors, host cells and recombinant proteins thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7129060B1 (en) * 1996-03-15 2006-10-31 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V Export systems for recombinant proteins
ATE346168T1 (de) 2001-03-02 2006-12-15 Univ Des Saarlandes Wissens Un Funktionelles oberflächendisplay von polypeptiden
GB0220199D0 (en) * 2002-08-30 2002-10-09 Univ Utrecht Mutant protein and refolding method
DK2255826T3 (en) * 2002-08-02 2016-06-20 Glaxosmithkline Biologicals Sa Neisserial vaccine compositions comprising a combination of antigens.
AU2003901316A0 (en) * 2003-03-21 2003-04-03 The Royal Alexandra Hospital For Children Regulation of cell surface proteins
DE602004028262D1 (de) * 2003-10-02 2010-09-02 Glaxosmithkline Biolog Sa B. pertussis antigene und ihre verwendung bei der vakzinierung
US7628995B2 (en) * 2003-12-23 2009-12-08 Glaxosmithkline Biologicals S.A. Outer membrane vesicles and uses thereof
ES2301262B1 (es) * 2004-01-14 2009-05-29 Consejo Sup. Investig. Cientificas Generacion de adhesion especifica en bacterias gram negativas mediante el anclaje de monodominos de inmunoglobulinas en su superficie con autotransportadores.
US8029777B2 (en) * 2004-08-13 2011-10-04 Marshall Barry J Helicobacter system and uses thereof
US9259463B2 (en) * 2006-01-16 2016-02-16 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Chlamydia vaccine
US8293685B2 (en) * 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
US9482663B2 (en) * 2009-09-09 2016-11-01 Autodisplay Biotech Gmbh Method for binding a recombinant polypeptide to a carrier
US8771669B1 (en) * 2010-02-09 2014-07-08 David Gordon Bermudes Immunization and/or treatment of parasites and infectious agents by live bacteria
ES2663872T3 (es) * 2010-03-11 2018-04-17 Glaxosmithkline Biologicals S.A. Composición inmunogénica o vacuna contra infección o enfermedad bacteriana gramnegativa, por ejemplo, por Neisseria
EP2619306B1 (en) * 2010-09-23 2015-05-20 Autodisplay Biotech GmbH Surface display of polypeptides containing a metal porphyrin or a flavin

Also Published As

Publication number Publication date
HK1187369A1 (en) 2014-04-04
EP2622078B1 (en) 2014-11-05
CN103228787B (zh) 2017-06-23
WO2012041899A1 (en) 2012-04-05
CA2811699C (en) 2019-07-02
US20130344099A1 (en) 2013-12-26
EP2622078A1 (en) 2013-08-07
CN103228787A (zh) 2013-07-31
CA2811699A1 (en) 2012-04-05
US9322011B2 (en) 2016-04-26
ES2529442T3 (es) 2015-02-20

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