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PL2656843T3 - Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie - Google Patents

Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie

Info

Publication number
PL2656843T3
PL2656843T3 PL12165728T PL12165728T PL2656843T3 PL 2656843 T3 PL2656843 T3 PL 2656843T3 PL 12165728 T PL12165728 T PL 12165728T PL 12165728 T PL12165728 T PL 12165728T PL 2656843 T3 PL2656843 T3 PL 2656843T3
Authority
PL
Poland
Prior art keywords
bendamustine
esters
related compounds
medical use
medical
Prior art date
Application number
PL12165728T
Other languages
English (en)
Inventor
Helmut Schickaneder
Armin Buschauer
Günther Bernhardt
Christian Schickaneder
Michael Limmert
Stefan Huber
Original Assignee
Synbias Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synbias Pharma Ag filed Critical Synbias Pharma Ag
Publication of PL2656843T3 publication Critical patent/PL2656843T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Hydrogenated Pyridines (AREA)
PL12165728T 2012-04-26 2012-04-26 Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie PL2656843T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12165728.2A EP2656843B1 (en) 2012-04-26 2012-04-26 Esters of bendamustine and related compounds, and medical use thereof

Publications (1)

Publication Number Publication Date
PL2656843T3 true PL2656843T3 (pl) 2015-08-31

Family

ID=46045872

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12165728T PL2656843T3 (pl) 2012-04-26 2012-04-26 Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie

Country Status (8)

Country Link
US (1) US8809549B2 (pl)
EP (1) EP2656843B1 (pl)
DK (1) DK2656843T3 (pl)
ES (1) ES2535511T3 (pl)
HR (1) HRP20150436T1 (pl)
PL (1) PL2656843T3 (pl)
PT (1) PT2656843E (pl)
SI (1) SI2656843T1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10526290B2 (en) 2012-06-19 2020-01-07 Synbias Pharma Ag Bendamustine derivatives and related compounds, and medical use thereof in cancer therapy
WO2014075035A1 (en) 2012-11-12 2014-05-15 Cephalon, Inc. Bendamustine derivatives and methods of using same
RU2672722C2 (ru) 2014-04-10 2018-11-19 Хубэй Био-Фармасьютикал Индастриал Текнолоджикал Инститьют Инк. Аналоги соединений 4н-пиразоло[1,5-а]бензимидазола в качестве ингибиторов parp
CA3013237A1 (en) * 2016-02-24 2017-08-31 Acesion Pharma Aps Novel potassium channel inhibitors
CA3078290A1 (en) 2017-10-05 2019-04-11 Tube Pharmaceuticals Gmbh Oral bendamustine formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
JP5773874B2 (ja) * 2008-10-08 2015-09-02 セファロン、インク． ベンダムスチンの調製方法
PL2367542T3 (pl) 2008-12-03 2014-05-30 Astellas Deutschland Gmbh Doustne formy dawkowania bendamustyny
CN101691359B (zh) 2009-09-30 2011-04-13 深圳万乐药业有限公司 一种高纯度的盐酸苯达莫司汀的合成方法
US9376394B2 (en) * 2009-12-23 2016-06-28 Dr. Reddy's Laboratories Ltd. Preparation of bendamustine and its salts
JO3659B1 (ar) 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
DE102010055499A1 (de) 2010-12-22 2011-06-16 W.C. Heraeus Gmbh Prozess zur Herstellung von Bendamustinalkylester, Bendarmustin sowie Derivaten davon

Also Published As

Publication number Publication date
PT2656843E (pt) 2015-04-14
US20130289032A1 (en) 2013-10-31
SI2656843T1 (sl) 2015-06-30
HRP20150436T1 (hr) 2015-05-22
EP2656843B1 (en) 2015-03-18
US8809549B2 (en) 2014-08-19
EP2656843A1 (en) 2013-10-30
ES2535511T3 (es) 2015-05-12
DK2656843T3 (en) 2015-04-20

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