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PL2644594T3 - Ukierunkowanie na komórki nowotworowe za pomocą nanocząstek - Google Patents

Ukierunkowanie na komórki nowotworowe za pomocą nanocząstek

Info

Publication number
PL2644594T3
PL2644594T3 PL13162789T PL13162789T PL2644594T3 PL 2644594 T3 PL2644594 T3 PL 2644594T3 PL 13162789 T PL13162789 T PL 13162789T PL 13162789 T PL13162789 T PL 13162789T PL 2644594 T3 PL2644594 T3 PL 2644594T3
Authority
PL
Poland
Prior art keywords
nanoparticles
macromolecules
cancer cell
cell targeting
directed
Prior art date
Application number
PL13162789T
Other languages
English (en)
Inventor
Stephen E Zale
Mir Mukkaram Ali
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PL2644594T3 publication Critical patent/PL2644594T3/pl

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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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