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PL2512470T3 - Oszczędzające ppar tiazolidynodiony i połączenia do leczenia chorób neurodegeneracyjnych - Google Patents

Oszczędzające ppar tiazolidynodiony i połączenia do leczenia chorób neurodegeneracyjnych

Info

Publication number
PL2512470T3
PL2512470T3 PL10798884T PL10798884T PL2512470T3 PL 2512470 T3 PL2512470 T3 PL 2512470T3 PL 10798884 T PL10798884 T PL 10798884T PL 10798884 T PL10798884 T PL 10798884T PL 2512470 T3 PL2512470 T3 PL 2512470T3
Authority
PL
Poland
Prior art keywords
ppar
combinations
treatment
neurodegenerative diseases
thiazolidinediones
Prior art date
Application number
PL10798884T
Other languages
English (en)
Inventor
Gerard R. Colca
Rolf F. KLETZIEN
Steven P. Tanis
Scott D. Larsen
Original Assignee
Octeta Therapeutics, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octeta Therapeutics, Llc filed Critical Octeta Therapeutics, Llc
Publication of PL2512470T3 publication Critical patent/PL2512470T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL10798884T 2009-12-15 2010-12-15 Oszczędzające ppar tiazolidynodiony i połączenia do leczenia chorób neurodegeneracyjnych PL2512470T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28676509P 2009-12-15 2009-12-15
US28671309P 2009-12-15 2009-12-15

Publications (1)

Publication Number Publication Date
PL2512470T3 true PL2512470T3 (pl) 2017-06-30

Family

ID=43589788

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10798884T PL2512470T3 (pl) 2009-12-15 2010-12-15 Oszczędzające ppar tiazolidynodiony i połączenia do leczenia chorób neurodegeneracyjnych

Country Status (15)

Country Link
US (1) US20130053350A1 (pl)
EP (2) EP3202401B1 (pl)
JP (1) JP2013514368A (pl)
KR (1) KR20120103711A (pl)
CN (1) CN102791269A (pl)
AU (1) AU2010331926B2 (pl)
CA (1) CA2783556C (pl)
DK (1) DK2512470T3 (pl)
ES (1) ES2617704T3 (pl)
HU (1) HUE033199T2 (pl)
MX (1) MX2012006730A (pl)
NZ (1) NZ600421A (pl)
PL (1) PL2512470T3 (pl)
RU (1) RU2570424C2 (pl)
WO (1) WO2011075514A1 (pl)

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ES2658168T3 (es) 2009-12-15 2018-03-08 Cirius Therapeutics, Inc. Sales de tiazolidinadiona ahorradoras de PPAR para el tratamiento de enfermedades metabólicas
US9072746B2 (en) 2010-04-22 2015-07-07 The Board Of Trustees Of The Leland Stanford Junior University Method for enhancing learning and memory impaired by neurodegenerative disorders and compounds and compositions for effecting the same
US9907767B2 (en) 2010-08-03 2018-03-06 Velicept Therapeutics, Inc. Pharmaceutical compositions and the treatment of overactive bladder
US9504679B2 (en) 2011-12-19 2016-11-29 Bjoern Colin Kahrs Pharmaceutical compositions comprising glitazones and Nrf2 activators
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
SG11201408323RA (en) * 2012-06-15 2015-01-29 Found Biomedical Res & Innov Prophylactic and/or therapeutic agent for mild cognitive impairment
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
EP2931274A1 (en) * 2012-12-11 2015-10-21 Metabolic Solutions Development Company LLC Ppar-sparing thiazolidinediones and combinations for the treatment of neurodegenerative diseases
SG10201705097PA (en) 2012-12-21 2017-07-28 Sanofi Sa Functionalized exendin-4 derivatives
CN105764884B (zh) * 2013-07-22 2019-01-18 新陈代谢解决方案开发公司 用于治疗代谢疾病的ppar-节制性化合物
TW201609796A (zh) 2013-12-13 2016-03-16 賽諾菲公司 非醯化之艾塞那肽-4(exendin-4)胜肽類似物
WO2015086728A1 (en) 2013-12-13 2015-06-18 Sanofi Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
TW201609797A (zh) 2013-12-13 2016-03-16 賽諾菲公司 雙重glp-1/升糖素受體促效劑
EP3080154B1 (en) 2013-12-13 2018-02-07 Sanofi Dual glp-1/gip receptor agonists
CN106456649A (zh) 2014-02-18 2017-02-22 莱兰斯坦福初级大学评议会 用于改善具有神经障碍的人的认知和社交行为的化合物
LT3388064T (lt) * 2014-04-02 2021-05-25 Minoryx Therapeutics S.L. 2,4-tiazolidindiono dariniai centrinės nervų sistemos sutrikimų gydyme
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自exendin-4之雙重glp-1/升糖素受體促效劑
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
AR105284A1 (es) 2015-07-10 2017-09-20 Sanofi Sa Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
FI3365321T3 (fi) 2015-10-23 2024-01-02 B3Ar Therapeutics Inc Solabegron-Zwitterioni ja sen käyttöjä
WO2019154958A1 (en) 2018-02-08 2019-08-15 Enyo Pharma Use of modulators of neet proteins for the treatment of infection
US20210251923A1 (en) * 2018-06-14 2021-08-19 Curasen Therapeutics, Inc. Methods for improving neurological diseases and disorders
CN111803502A (zh) * 2020-06-30 2020-10-23 安域生物制药(杭州)有限公司 去甲乌药碱预防及治疗阿尔茨海默病的应用
CN112587664A (zh) * 2020-12-29 2021-04-02 四川大学华西医院 长链脂酰辅酶a合成酶4的抑制剂在治疗帕金森疾病中的应用
CN115531368A (zh) * 2021-06-14 2022-12-30 谭文 R-氨基甲酸酯-β-苯乙醇胺类化合物治疗学习和记忆缺陷以及神经退行性疾病的应用

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US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5886026A (en) 1993-07-19 1999-03-23 Angiotech Pharmaceuticals Inc. Anti-angiogenic compositions and methods of use
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
GB0023971D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical
US20060089387A1 (en) * 2004-10-26 2006-04-27 Le Huang Stabilized pharmaceutical composition comprising antidiabetic agent
ES2654908T3 (es) * 2006-03-16 2018-02-15 Metabolic Solutions Development Company Llc Análogos de tiazolidindiona para el tratamiento de enfermedades mediadas por una inflamación metabólica
EP2001469B1 (en) * 2006-03-16 2012-05-23 Metabolic Solutions Development Company LLC Thiazolidinedione analogues
EP2001470A2 (en) * 2006-03-16 2008-12-17 Metabolic Solutions Development Company Combination therapies of thiazolidinedione analogues
BRPI0817096B8 (pt) * 2007-09-14 2021-05-25 Cirius Therapeutics Inc análogo de tiazolidinodiona e composição farmacêutica que o compreende
WO2010105048A1 (en) * 2009-03-12 2010-09-16 Metabolic Solutions Development Company Thiazolidinedione analogues

Also Published As

Publication number Publication date
EP2512470B1 (en) 2016-11-30
DK2512470T3 (en) 2017-02-27
CN102791269A (zh) 2012-11-21
AU2010331926B2 (en) 2014-03-27
US20130053350A1 (en) 2013-02-28
WO2011075514A1 (en) 2011-06-23
JP2013514368A (ja) 2013-04-25
EP3202401B1 (en) 2019-10-23
EP2512470A1 (en) 2012-10-24
CA2783556A1 (en) 2011-06-23
NZ600421A (en) 2014-06-27
AU2010331926A1 (en) 2012-06-21
ES2617704T3 (es) 2017-06-19
EP3202401A1 (en) 2017-08-09
CA2783556C (en) 2017-12-12
MX2012006730A (es) 2012-07-30
RU2012129931A (ru) 2014-01-27
HUE033199T2 (en) 2017-11-28
RU2570424C2 (ru) 2015-12-10
KR20120103711A (ko) 2012-09-19

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