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PL2460801T3 - Związek bicykliczny i jego zastosowanie do celów medycznych - Google Patents

Związek bicykliczny i jego zastosowanie do celów medycznych

Info

Publication number
PL2460801T3
PL2460801T3 PL10804397T PL10804397T PL2460801T3 PL 2460801 T3 PL2460801 T3 PL 2460801T3 PL 10804397 T PL10804397 T PL 10804397T PL 10804397 T PL10804397 T PL 10804397T PL 2460801 T3 PL2460801 T3 PL 2460801T3
Authority
PL
Poland
Prior art keywords
medical purposes
bicyclic compound
bicyclic
compound
medical
Prior art date
Application number
PL10804397T
Other languages
English (en)
Inventor
Tohru Kambe
Toru Maruyama
Shinsaku Yamane
Satoshi Nakayama
Kousuke Tani
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of PL2460801T3 publication Critical patent/PL2460801T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/902Method of implanting
    • Y10S623/905Eye

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
  • Image Processing (AREA)
PL10804397T 2009-07-28 2010-07-27 Związek bicykliczny i jego zastosowanie do celów medycznych PL2460801T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009175246 2009-07-28
PCT/JP2010/062587 WO2011013651A1 (ja) 2009-07-28 2010-07-27 二環式化合物およびその医薬用途
EP10804397.7A EP2460801B1 (en) 2009-07-28 2010-07-27 Bicyclic compound and use thereof for medical purposes

Publications (1)

Publication Number Publication Date
PL2460801T3 true PL2460801T3 (pl) 2014-11-28

Family

ID=43529306

Family Applications (2)

Application Number Title Priority Date Filing Date
PL13003505T PL2653468T3 (pl) 2009-07-28 2010-07-27 Bicykliczny związek i jego zastosowania do celów medycznych
PL10804397T PL2460801T3 (pl) 2009-07-28 2010-07-27 Związek bicykliczny i jego zastosowanie do celów medycznych

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL13003505T PL2653468T3 (pl) 2009-07-28 2010-07-27 Bicykliczny związek i jego zastosowania do celów medycznych

Country Status (20)

Country Link
US (10) US8614340B2 (pl)
EP (2) EP2460801B1 (pl)
JP (3) JP5652397B2 (pl)
KR (1) KR101768235B1 (pl)
CN (1) CN102498105B (pl)
AU (1) AU2010279183B2 (pl)
BR (1) BR112012001797B1 (pl)
CA (1) CA2767083C (pl)
DK (2) DK2460801T3 (pl)
ES (2) ES2500067T3 (pl)
HU (1) HUE028874T2 (pl)
IL (1) IL217342A (pl)
MX (1) MX2012000889A (pl)
NZ (1) NZ597626A (pl)
PL (2) PL2653468T3 (pl)
PT (1) PT2460801E (pl)
RU (1) RU2540330C2 (pl)
TW (1) TWI466877B (pl)
WO (1) WO2011013651A1 (pl)
ZA (1) ZA201200797B (pl)

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JP5652397B2 (ja) * 2009-07-28 2015-01-14 小野薬品工業株式会社 二環式化合物およびその医薬用途
JP5835236B2 (ja) * 2011-01-27 2015-12-24 小野薬品工業株式会社 二環式化合物およびその医薬用途
WO2012102355A1 (ja) 2011-01-27 2012-08-02 小野薬品工業株式会社 二環式化合物およびその医薬用途
US9944217B2 (en) 2013-02-11 2018-04-17 Ferno-Washington, Inc. Equipment mounting system
US9890146B2 (en) 2014-02-27 2018-02-13 Ono Pharmaceutical Co., Ltd. Compound having selective EP2 agonist activity
EP3327018B1 (en) * 2015-07-23 2020-11-25 ONO Pharmaceutical Co., Ltd. 2-(octahydrocyclopenta[b]pyran-2-yl)1,3-thiazole-4-carboxylic acid derivatives and related compounds as ep2 agonists with intraocular pressure lowering activity
RU2738646C2 (ru) * 2016-04-01 2020-12-15 РЕКЬЮРИУМ АйПи ХОЛДИНГС, ЛЛС Модуляторы эстрогеновых рецепторов
ES2890989T3 (es) * 2016-06-30 2022-01-25 Ono Pharmaceutical Co Método para producir un compuesto bicíclico
EP3730138B1 (en) 2017-12-21 2024-02-14 Santen Pharmaceutical Co., Ltd. Combination of sepetaprost and ripasudil for use in the prophylaxis or treatment of glaucoma or ocular hypertension
WO2019124489A1 (ja) * 2017-12-21 2019-06-27 参天製薬株式会社 セペタプロストとep2アゴニストとの組み合わせ医薬
CA3085747A1 (en) * 2017-12-21 2019-06-27 Ono Pharmaceutical Co., Ltd. Therapeutic agent for glaucoma comprising fp agonist and .beta.-blocker
CN116159601B (zh) * 2019-03-15 2024-07-23 博瑞生物医药(苏州)股份有限公司 艾日布林中间体及其制备方法
CA3154867A1 (en) * 2019-09-19 2021-03-25 Polyactiva Pty Ltd Biodegradable drug-polymer conjugate
ES3015621T3 (en) 2019-12-31 2025-05-06 Ind Tech Res Inst Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and use of the same
WO2021145356A1 (ja) * 2020-01-15 2021-07-22 参天製薬株式会社 近視の治療、近視の予防および/または近視の進行抑制のための医薬組成物
WO2022034909A1 (ja) 2020-08-13 2022-02-17 参天製薬株式会社 セペタプロストを含有する医薬製剤
CN116947725A (zh) * 2022-04-14 2023-10-27 广州楷石医药有限公司 曲伏前列素的合成方法
WO2023204297A1 (ja) 2022-04-22 2023-10-26 参天製薬株式会社 セペタプロストを含有する眼科用組成物
WO2025159135A1 (ja) * 2024-01-24 2025-07-31 参天製薬株式会社 緑内障または高眼圧症に罹患している患者における夜間睡眠時の眼圧を下降させるためのセペタプロストを含有する点眼液

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CN102336754B (zh) 2010-07-15 2017-04-12 浙江奥翔药业股份有限公司 恩替卡韦的合成方法及其中间体化合物
JP5835236B2 (ja) 2011-01-27 2015-12-24 小野薬品工業株式会社 二環式化合物およびその医薬用途
WO2012102355A1 (ja) 2011-01-27 2012-08-02 小野薬品工業株式会社 二環式化合物およびその医薬用途
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ES2890989T3 (es) * 2016-06-30 2022-01-25 Ono Pharmaceutical Co Método para producir un compuesto bicíclico

Also Published As

Publication number Publication date
US20160287551A1 (en) 2016-10-06
TWI466877B (zh) 2015-01-01
US20210169842A1 (en) 2021-06-10
CN102498105B (zh) 2014-04-02
JP5652397B2 (ja) 2015-01-14
US9388157B2 (en) 2016-07-12
AU2010279183B2 (en) 2015-10-29
US20140073676A1 (en) 2014-03-13
US12201603B2 (en) 2025-01-21
MX2012000889A (es) 2012-02-13
IL217342A (en) 2016-03-31
PL2653468T3 (pl) 2016-08-31
RU2540330C2 (ru) 2015-02-10
KR20120038986A (ko) 2012-04-24
JP2015052011A (ja) 2015-03-19
US20180116995A1 (en) 2018-05-03
US20120122964A1 (en) 2012-05-17
RU2012107109A (ru) 2013-09-10
EP2460801B1 (en) 2014-06-25
BR112012001797B1 (pt) 2020-04-07
EP2460801A1 (en) 2012-06-06
JP2016188217A (ja) 2016-11-04
US9889114B2 (en) 2018-02-13
EP2653468B1 (en) 2016-02-24
JP5935857B2 (ja) 2016-06-15
BR112012001797A2 (pt) 2017-05-16
US20150112079A1 (en) 2015-04-23
US20230190698A1 (en) 2023-06-22
US8614340B2 (en) 2013-12-24
IL217342A0 (en) 2012-02-29
US10201520B2 (en) 2019-02-12
US20200093781A1 (en) 2020-03-26
CN102498105A (zh) 2012-06-13
US20250099419A1 (en) 2025-03-27
CA2767083A1 (en) 2011-02-03
DK2460801T3 (da) 2014-09-22
ES2500067T3 (es) 2014-09-30
US11617733B2 (en) 2023-04-04
HK1170487A1 (en) 2013-03-01
TW201109311A (en) 2011-03-16
ES2567328T3 (es) 2016-04-21
WO2011013651A1 (ja) 2011-02-03
PT2460801E (pt) 2014-08-29
NZ597626A (en) 2013-03-28
CA2767083C (en) 2017-05-16
DK2653468T3 (en) 2016-06-06
HUE028874T2 (en) 2017-01-30
AU2010279183A1 (en) 2012-02-02
JPWO2011013651A1 (ja) 2013-01-07
US20190111019A1 (en) 2019-04-18
US8962868B2 (en) 2015-02-24
KR101768235B1 (ko) 2017-08-14
ZA201200797B (en) 2012-10-31
EP2460801A4 (en) 2013-01-02
US10940134B2 (en) 2021-03-09
EP2653468A1 (en) 2013-10-23
JP6149975B2 (ja) 2017-06-21

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