PL2448600T3 - Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu - Google Patents
Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanuInfo
- Publication number
- PL2448600T3 PL2448600T3 PL10727003.5T PL10727003T PL2448600T3 PL 2448600 T3 PL2448600 T3 PL 2448600T3 PL 10727003 T PL10727003 T PL 10727003T PL 2448600 T3 PL2448600 T3 PL 2448600T3
- Authority
- PL
- Poland
- Prior art keywords
- cation
- compounds targeting
- phosphate receptor
- independent mannose
- mannose
- Prior art date
Links
- 102100037182 Cation-independent mannose-6-phosphate receptor Human genes 0.000 title 1
- 101710145225 Cation-independent mannose-6-phosphate receptor Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305647 | 2009-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2448600T3 true PL2448600T3 (pl) | 2016-10-31 |
Family
ID=41279432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10727003.5T PL2448600T3 (pl) | 2009-07-03 | 2010-07-02 | Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8962573B2 (pl) |
| EP (1) | EP2448600B1 (pl) |
| JP (1) | JP5837486B2 (pl) |
| CA (1) | CA2766614C (pl) |
| ES (1) | ES2576853T3 (pl) |
| PL (1) | PL2448600T3 (pl) |
| WO (1) | WO2011000958A1 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011242461B2 (en) | 2010-04-23 | 2015-10-01 | Alexion Pharmaceuticals, Inc. | Lysosomal storage disease enzyme |
| AR082953A1 (es) | 2010-09-09 | 2013-01-23 | Synageva Biopharma Corp | Metodos para tratar deficiencia de acido lisosomal lipasa en pacientes |
| JP5665065B2 (ja) * | 2011-04-28 | 2015-02-04 | 国立大学法人大阪大学 | リソソーム病治療用医薬組成物 |
| RU2014117291A (ru) | 2011-10-12 | 2015-11-20 | Синаджева Биофарма Корп. | Рекомбинантный человеческий белок naglu и его применение |
| CA2881420C (en) | 2012-08-16 | 2016-11-15 | Pfizer Inc. | Glycoconjugation processes and compositions |
| CN102993256B (zh) * | 2012-12-31 | 2016-05-18 | 浙江大学 | 一种选择性脱除全三甲基硅基保护糖的伯位三甲基硅基的方法 |
| AU2014235004B2 (en) * | 2013-03-15 | 2018-08-16 | Newlink Genetics Corporation | Carbohydrate-modified glycoproteins and uses thereof |
| FR3041345B1 (fr) | 2015-09-18 | 2019-06-14 | Nanomedsyn | Composes polysaccharides multi-fonctionnalises et leur utilisation pour cibler le recepteur du mannose 6-phosphate cation-independant |
| HK1253529A1 (zh) * | 2015-11-06 | 2019-06-21 | Biomarin Pharmaceutical Inc. | 用於检测中和溶酶体酶的摄取的抗体或其它因子的基於细胞的测定 |
| JP7466927B2 (ja) * | 2018-08-10 | 2024-04-15 | ニューヨーク ユニバーシティ | アンジェルマン症候群及び自閉症を治療するためのｉｇｆ―２受容体作動剤リガンドの使用 |
| KR20210075069A (ko) * | 2018-08-10 | 2021-06-22 | 뉴욕 유니버시티 | 기억력 향상 및 기억력 손상 감소를 위한 만노오스 6 포스페이트 및 이의 변형물의 용도 |
| EP3897747A4 (en) * | 2018-12-19 | 2022-12-07 | The Board of Trustees of the Leland Stanford Junior University | BIFUNCTIONAL MOLECULES FOR LYSOSOMA TARGETING AND RELATED COMPOSITIONS AND METHODS |
| CN110893236A (zh) * | 2019-10-09 | 2020-03-20 | 中山大学 | 溶酶体靶向的抗体药物偶联物及其应用 |
| CA3167272A1 (en) * | 2020-01-10 | 2021-07-15 | Lycia Therapeutics, Inc. | Cell surface receptor binding compounds and conjugates |
| US20230226214A1 (en) * | 2020-06-24 | 2023-07-20 | Lycia Therapeutics, Inc. | Bifunctional bridging compositions for viral transduction |
| EP4171658A4 (en) * | 2020-06-24 | 2025-04-09 | Lycia Therapeutics, Inc. | Modified viral compositions for viral transduction |
| EP4370157A1 (en) | 2021-07-14 | 2024-05-22 | Lycia Therapeutics, Inc. | Asgpr cell surface receptor binding compounds and conjugates |
| FR3132634B1 (fr) | 2022-02-15 | 2025-04-25 | Nanomedsyn | Composés bifonctionnels ciblant le récepteur du mannose 6-phosphate cation-indépendant |
| FR3146400A1 (fr) | 2023-03-07 | 2024-09-13 | Nanomedsyn | Conjugués ciblant le récepteur du mannose 6-phosphate cation-indépendant et le tissu osseux |
| FR3149188A1 (fr) | 2023-05-31 | 2024-12-06 | Nanomedsyn | Pro-ligands, conjugués comprenant lesdits pro-ligands et leurs utilisations pour des applications thérapeutiques |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6844319B1 (en) * | 1998-10-08 | 2005-01-18 | Stichting Voor De Technische Wetenschappen | Peptide-based carrier devices for stellate cells |
| US7001994B2 (en) | 2001-01-18 | 2006-02-21 | Genzyme Corporation | Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins |
| US7365178B2 (en) | 2003-04-01 | 2008-04-29 | Activx Biosciences, Inc. | Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis |
| EP1495769B1 (en) | 2003-07-11 | 2008-02-27 | LBR Medbiotech B.V. | Mannose-6-phosphate receptor mediated gene transfer into muscle cells |
| GB0326546D0 (en) * | 2003-11-14 | 2003-12-17 | Amersham Plc | Inhibitor imaging agents |
| CA2571431A1 (en) | 2004-06-24 | 2006-01-05 | The Scripps Research Institute | Arrays with cleavable linkers |
| WO2008089339A2 (en) | 2007-01-18 | 2008-07-24 | Genzyme Corporation | Oligosaccharide conjugates for cellular targeting |
| PT2121713E (pt) | 2007-01-18 | 2013-06-25 | Genzyme Corp | Oligossacáridos compreendendo um grupo aminooxi e seus conjugados |
| JP5069920B2 (ja) | 2007-02-08 | 2012-11-07 | 公益財団法人東京都医学総合研究所 | マンノース６−リン酸−ポリエチレングリコール結合体 |
| WO2008125615A1 (en) * | 2007-04-11 | 2008-10-23 | Merck Eprova Ag | 18 f-labelled folates |
| BRPI0815324A2 (pt) * | 2007-08-20 | 2015-07-14 | Protalix Ltd | "conjugado protêico que contém sacarídeos, processo de separação do conjugado protêico que contém sacarídeos, composição farmacêutica do conjugado protêico que contém sacarídeos, uso do conjugado protêico que contém sacarídeos e composto do conjugado protêico que contém sacarídeos" |
-
2010
- 2010-07-02 CA CA2766614A patent/CA2766614C/en active Active
- 2010-07-02 EP EP10727003.5A patent/EP2448600B1/en active Active
- 2010-07-02 US US13/380,199 patent/US8962573B2/en active Active
- 2010-07-02 PL PL10727003.5T patent/PL2448600T3/pl unknown
- 2010-07-02 JP JP2012518097A patent/JP5837486B2/ja active Active
- 2010-07-02 ES ES10727003.5T patent/ES2576853T3/es active Active
- 2010-07-02 WO PCT/EP2010/059507 patent/WO2011000958A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2448600B1 (en) | 2016-03-30 |
| JP5837486B2 (ja) | 2015-12-24 |
| WO2011000958A1 (en) | 2011-01-06 |
| JP2012531458A (ja) | 2012-12-10 |
| EP2448600A1 (en) | 2012-05-09 |
| US8962573B2 (en) | 2015-02-24 |
| US20120093795A1 (en) | 2012-04-19 |
| ES2576853T3 (es) | 2016-07-11 |
| CA2766614C (en) | 2018-06-19 |
| CA2766614A1 (en) | 2011-01-06 |
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