PL2329848T3 - Liksysenatyd z insuliną glargine i metforminą jako terapia skojarzona do leczenia cukrzycy typu 2 - Google Patents

Liksysenatyd z insuliną glargine i metforminą jako terapia skojarzona do leczenia cukrzycy typu 2

Info

Publication number: PL2329848T3
Authority: PL; Poland
Prior art keywords: lixisenatide; metformin; diabetes; therapy; add
Prior art date: 2009-11-13

Application number

PL09175877T

Other languages

English (en)

Other versions

PL2329848T5 (pl

Inventor

Louise Silvestre

Elisabeth Souhami

Xiaodan Wei

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-11-13

Filing date

2009-11-13

Publication date

2013-05-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41800749&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2329848(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-11-13 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2013-05-31 Publication of PL2329848T3 publication Critical patent/PL2329848T3/pl

2019-12-31 Publication of PL2329848T5 publication Critical patent/PL2329848T5/pl

Links

108010057186 Insulin Glargine Proteins 0.000 title 1
COCFEDIXXNGUNL-RFKWWTKHSA-N Insulin glargine Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(=O)NCC(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 COCFEDIXXNGUNL-RFKWWTKHSA-N 0.000 title 1
XVVOERDUTLJJHN-UHFFFAOYSA-N Lixisenatide Chemical compound C=1NC2=CC=CC=C2C=1CC(C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NCC(=O)NCC(=O)N1C(CCC1)C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N1C(CCC1)C(=O)N1C(CCC1)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)CC)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C(NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCSC)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CC=1C=CC=CC=1)NC(=O)C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)CNC(=O)C(N)CC=1NC=NC=1)C(C)O)C(C)O)C(C)C)CC1=CC=CC=C1 XVVOERDUTLJJHN-UHFFFAOYSA-N 0.000 title 1
229960002869 insulin glargine Drugs 0.000 title 1
229960001093 lixisenatide Drugs 0.000 title 1
108010004367 lixisenatide Proteins 0.000 title 1
XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title 1
229960003105 metformin Drugs 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
208000001072 type 2 diabetes mellitus Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Immunology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Diabetes (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL09175877T 2009-11-13 2009-11-13 Liksysenatyd z insuliną glargine i metforminą jako terapia skojarzona do leczenia cukrzycy typu 2 PL2329848T5 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP09175877.1A EP2329848B2 (en)	2009-11-13	2009-11-13	Lixisenatide as add-on therapy to insulin glargine and metformin for treating type 2 diabetes

Publications (2)

Publication Number	Publication Date
PL2329848T3 true PL2329848T3 (pl)	2013-05-31
PL2329848T5 PL2329848T5 (pl)	2019-12-31

Family

ID=41800749

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL09175877T PL2329848T5 (pl)	2009-11-13	2009-11-13	Liksysenatyd z insuliną glargine i metforminą jako terapia skojarzona do leczenia cukrzycy typu 2

Country Status (11)

Country	Link
EP (1)	EP2329848B2 (pl)
CY (1)	CY1113755T1 (pl)
DK (1)	DK2329848T4 (pl)
ES (1)	ES2398012T5 (pl)
HR (1)	HRP20121029T4 (pl)
ME (1)	ME01546B (pl)
PL (1)	PL2329848T5 (pl)
PT (1)	PT2329848E (pl)
RS (1)	RS52629B2 (pl)
SI (1)	SI2329848T2 (pl)
SM (1)	SMT201300013B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LT3228320T (lt)	2008-10-17	2020-03-10	Sanofi-Aventis Deutschland Gmbh	Insulino ir glp-1 agonisto derinys
PL2498802T3 (pl)	2009-11-13	2015-06-30	Sanofi Aventis Deutschland	Kompozycja farmaceutyczna zawierająca agonistę GLP-1, insulinę i metioninę
EP2498801B1 (de)	2009-11-13	2018-01-24	Sanofi-Aventis Deutschland GmbH	HARMAZEUTISCHE ZUSAMMENSETZUNG UMFASSEND desPro36Exendin-4(1-39)-Lys6-NH2 UND METHIONIN
AU2011202239C1 (en)	2010-05-19	2017-03-16	Sanofi	Long-acting formulations of insulins
SI2611458T1 (sl)	2010-08-30	2017-01-31	Sanofi-Aventis Deutschland Gmbh	Uporaba AVE0010 za izdelavo zdravila za zdravljenje sladkorne bolezni tipa 2
MX2013008484A (es) *	2011-02-02	2013-08-12	Sanofi Aventis Deutschland	Prevencion de hidroglucemia en pacientes con diabetes mellitus tipo 2.
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
HUE027989T2 (en)	2011-08-29	2016-11-28	Sanofi Aventis Deutschland	A pharmaceutical composition for use in glycemic control in patients with type 2 diabetes
AR087744A1 (es)	2011-09-01	2014-04-16	Sanofi Aventis Deutschland	Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
MY170713A (en) *	2011-10-28	2019-08-27	Sanofi Aventis Deutschland	Treatment protocol of diabetes type 2
EP3517122A1 (en)	2013-04-03	2019-07-31	Sanofi	Treatment of diabetes mellitus by long-acting formulations of insulins
LT3010530T (lt) *	2013-06-17	2019-04-10	Sanofi-Aventis Deutschland Gmbh	Kompozicija su fiksuotu insulino glargino / liksisenatido santikiu
CA2970200A1 (en)	2014-12-12	2016-06-16	Sanofi-Aventis Deutschland Gmbh	Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1076066A1 (en)	1999-07-12	2001-02-14	Zealand Pharmaceuticals A/S	Peptides for lowering blood glucose levels

2009
- 2009-11-13 DK DK09175877.1T patent/DK2329848T4/da active
- 2009-11-13 RS RS20120571 patent/RS52629B2/sr unknown
- 2009-11-13 PL PL09175877T patent/PL2329848T5/pl unknown
- 2009-11-13 SI SI200930473T patent/SI2329848T2/sl unknown
- 2009-11-13 EP EP09175877.1A patent/EP2329848B2/en active Active
- 2009-11-13 PT PT91758771T patent/PT2329848E/pt unknown
- 2009-11-13 ME MEP-2012-147A patent/ME01546B/me unknown
- 2009-11-13 ES ES09175877T patent/ES2398012T5/es active Active
2012
- 2012-12-13 HR HRP20121029TT patent/HRP20121029T4/hr unknown
2013
- 2013-01-09 CY CY20131100022T patent/CY1113755T1/el unknown
- 2013-01-30 SM SM201300013T patent/SMT201300013B/xx unknown

Also Published As

Publication number	Publication date
DK2329848T4 (da)	2019-09-09
PT2329848E (pt)	2013-01-23
EP2329848B1 (en)	2012-10-24
EP2329848B2 (en)	2019-06-19
ES2398012T3 (es)	2013-03-13
SI2329848T2 (sl)	2019-10-30
RS52629B2 (sr)	2019-11-29
PL2329848T5 (pl)	2019-12-31
CY1113755T1 (el)	2016-07-27
ES2398012T5 (es)	2020-02-26
ME01546B (me)	2014-04-20
RS52629B (en)	2013-06-28
DK2329848T3 (da)	2013-02-04
EP2329848A1 (en)	2011-06-08
SMT201300013B (it)	2013-03-08
SI2329848T1 (sl)	2013-02-28
HRP20121029T1 (hr)	2013-01-31
HRP20121029T4 (hr)	2019-10-18

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