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PL2134743T3 - Ulepszone szczepionki przeciw Bordetella pertussis oparte na mutantach glikozylo-transferazy LPS - Google Patents

Ulepszone szczepionki przeciw Bordetella pertussis oparte na mutantach glikozylo-transferazy LPS

Info

Publication number
PL2134743T3
PL2134743T3 PL08723920T PL08723920T PL2134743T3 PL 2134743 T3 PL2134743 T3 PL 2134743T3 PL 08723920 T PL08723920 T PL 08723920T PL 08723920 T PL08723920 T PL 08723920T PL 2134743 T3 PL2134743 T3 PL 2134743T3
Authority
PL
Poland
Prior art keywords
improved
bordetella pertussis
vaccines based
pertussis vaccines
lps
Prior art date
Application number
PL08723920T
Other languages
English (en)
Inventor
Jeroen Johannes Gerardus Geurtsen
Johannes Petrus Maria Tommassen
Der Ley Peter André Van
Original Assignee
De Staat Der Nederlanden Vert Door De Mini Van Vws
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by De Staat Der Nederlanden Vert Door De Mini Van Vws filed Critical De Staat Der Nederlanden Vert Door De Mini Van Vws
Publication of PL2134743T3 publication Critical patent/PL2134743T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K2039/10Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL08723920T 2007-03-26 2008-03-25 Ulepszone szczepionki przeciw Bordetella pertussis oparte na mutantach glikozylo-transferazy LPS PL2134743T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07104885 2007-03-26
PCT/NL2008/050169 WO2008118015A2 (en) 2007-03-26 2008-03-25 Improved vaccines against bordetella pertussis based on lps glycosyltransferase mutants
EP08723920A EP2134743B1 (en) 2007-03-26 2008-03-25 Improved vaccines against bordetella pertussis based on lps glycosyltransferase mutants

Publications (1)

Publication Number Publication Date
PL2134743T3 true PL2134743T3 (pl) 2013-01-31

Family

ID=38134330

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08723920T PL2134743T3 (pl) 2007-03-26 2008-03-25 Ulepszone szczepionki przeciw Bordetella pertussis oparte na mutantach glikozylo-transferazy LPS

Country Status (17)

Country Link
US (1) US9296995B2 (pl)
EP (1) EP2134743B1 (pl)
JP (1) JP5683260B2 (pl)
KR (1) KR101667551B1 (pl)
CN (1) CN101801997B (pl)
AU (1) AU2008230238B2 (pl)
BR (1) BRPI0809321A2 (pl)
CA (1) CA2681924C (pl)
ES (1) ES2393682T3 (pl)
IL (1) IL201241A (pl)
MX (1) MX2009010347A (pl)
NZ (1) NZ579940A (pl)
PL (1) PL2134743T3 (pl)
PT (1) PT2134743E (pl)
RU (1) RU2542667C2 (pl)
SI (1) SI2134743T1 (pl)
WO (1) WO2008118015A2 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11078257B2 (en) 2016-07-29 2021-08-03 The Regents Of The University Of Michigan Recombinant gram negative bacteria and methods of generating and utilizing same
CA3055757A1 (en) * 2017-03-13 2018-09-20 De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport Bordetella vaccines comprising lps with reduced reactogenicity
US10398094B2 (en) * 2017-05-16 2019-09-03 Martin W. Taylor Impermeable sectional apparatus for soil moisture retention
CN110373438B (zh) * 2019-07-31 2021-05-04 江南大学 一种提高γ-氨基丁酸产量的方法
CN117947054B (zh) * 2024-03-25 2024-06-21 上海羽冠生物技术有限公司 一种百日咳鲍特菌无缝基因编辑的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2305799T3 (en) * 1998-02-27 2016-07-25 Novozymes As Maltogenic alpha-amylase variants
DK1127137T4 (da) * 1998-11-03 2014-02-10 Nederlanden Staat LPS med reduceret toksicitet fra genetisk modificerede gram-negative bakterier
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
CN101203605B (zh) * 2004-12-17 2016-01-27 由卫生福利和体育大臣代表的荷兰王国 革兰氏阴性菌的lps的脱酰基化

Also Published As

Publication number Publication date
CA2681924C (en) 2019-12-31
EP2134743A2 (en) 2009-12-23
IL201241A0 (en) 2010-05-31
US9296995B2 (en) 2016-03-29
BRPI0809321A2 (pt) 2014-09-23
JP2010522557A (ja) 2010-07-08
ES2393682T3 (es) 2012-12-27
MX2009010347A (es) 2009-12-10
KR101667551B1 (ko) 2016-10-19
WO2008118015A3 (en) 2009-06-25
NZ579940A (en) 2012-03-30
AU2008230238A1 (en) 2008-10-02
CN101801997A (zh) 2010-08-11
PT2134743E (pt) 2012-12-21
KR20100015812A (ko) 2010-02-12
AU2008230238B2 (en) 2013-06-06
WO2008118015A2 (en) 2008-10-02
CA2681924A1 (en) 2008-10-02
EP2134743B1 (en) 2012-09-05
IL201241A (en) 2015-02-26
CN101801997B (zh) 2016-06-01
SI2134743T1 (sl) 2013-01-31
RU2009139262A (ru) 2011-05-10
JP5683260B2 (ja) 2015-03-11
RU2542667C2 (ru) 2015-02-20
US20100291153A1 (en) 2010-11-18

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