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PL2126049T3 - Przeciwciała przeciwko ludzkiemu wirusowi cytomegalii (HCMV) - Google Patents

Przeciwciała przeciwko ludzkiemu wirusowi cytomegalii (HCMV)

Info

Publication number
PL2126049T3
PL2126049T3 PL07857724T PL07857724T PL2126049T3 PL 2126049 T3 PL2126049 T3 PL 2126049T3 PL 07857724 T PL07857724 T PL 07857724T PL 07857724 T PL07857724 T PL 07857724T PL 2126049 T3 PL2126049 T3 PL 2126049T3
Authority
PL
Poland
Prior art keywords
hcmv
human cytomegalovirus
antibodies against
against human
infections
Prior art date
Application number
PL07857724T
Other languages
English (en)
Inventor
Ada Funaro
Giorgio Gribaudo
Santo Landolfo
Original Assignee
Ribovax Biotechnologies Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2006/069780 external-priority patent/WO2007068758A1/en
Application filed by Ribovax Biotechnologies Sa filed Critical Ribovax Biotechnologies Sa
Publication of PL2126049T3 publication Critical patent/PL2126049T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/089Cytomegalovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL07857724T 2006-12-15 2007-12-17 Przeciwciała przeciwko ludzkiemu wirusowi cytomegalii (HCMV) PL2126049T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP2006/069780 WO2007068758A1 (en) 2005-12-16 2006-12-15 Methods for obtaining immortalized antibody secreting cells
EP07110693 2007-06-20
PCT/EP2007/064094 WO2008071806A1 (en) 2006-12-15 2007-12-17 Antibodies against human cytomegalovirus (hcmv)
EP07857724A EP2126049B1 (en) 2006-12-15 2007-12-17 Antibodies against human cytomegalovirus (hcmv)

Publications (1)

Publication Number Publication Date
PL2126049T3 true PL2126049T3 (pl) 2011-09-30

Family

ID=40935039

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07857724T PL2126049T3 (pl) 2006-12-15 2007-12-17 Przeciwciała przeciwko ludzkiemu wirusowi cytomegalii (HCMV)

Country Status (18)

Country Link
US (1) US8153129B2 (pl)
EP (1) EP2126049B1 (pl)
JP (1) JP5351041B2 (pl)
KR (1) KR20090114364A (pl)
CN (1) CN101627115B (pl)
AT (1) ATE503769T1 (pl)
AU (1) AU2007331463B2 (pl)
BR (1) BRPI0720464A2 (pl)
CA (1) CA2672703C (pl)
DE (1) DE602007013618D1 (pl)
DK (1) DK2126049T3 (pl)
EA (1) EA018701B1 (pl)
ES (1) ES2363992T3 (pl)
IL (1) IL199366A (pl)
NO (1) NO20092671L (pl)
PL (1) PL2126049T3 (pl)
PT (1) PT2126049E (pl)
WO (1) WO2008071806A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US20110171233A1 (en) * 2007-08-22 2011-07-14 Ribovax Biotechnologies S.A. Antibodies Against Human Cytomegalovirus (HCMV)
EP2352759B1 (en) 2008-07-16 2017-11-01 Institute for Research in Biomedicine Human cytomegalovirus neutralizing antibodies and use thereof
US8703486B2 (en) * 2008-09-23 2014-04-22 UNIVERSITé LAVAL Method for polyclonal immunoglobulin G production by human B cells
JP5833565B2 (ja) 2009-12-23 2015-12-16 4−アンティボディ・アクチェンゲゼルシャフト4−Antibody Ag ヒトサイトメガロウイルスに対する結合メンバー
AR083214A1 (es) * 2010-09-29 2013-02-06 Genentech Inc Composiciones de anticuerpo anti complejo i de hcmv y metodos de uso
KR20140138971A (ko) 2012-03-28 2014-12-04 제넨테크, 인크. 항-hcmv 이디오타입 항체 및 이들의 용도
KR101581158B1 (ko) 2014-03-26 2015-12-30 울산대학교 산학협력단 거대세포바이러스 실제 감염 여부를 진단하기 위한 거대세포바이러스의 감염 해석 모델
RU2699715C2 (ru) * 2014-05-19 2019-09-09 Ф. Хоффманн-Ля Рош Аг Способ получения полипептидов
US10611800B2 (en) 2016-03-11 2020-04-07 Pfizer Inc. Human cytomegalovirus gB polypeptide
US11629172B2 (en) 2018-12-21 2023-04-18 Pfizer Inc. Human cytomegalovirus gB polypeptide
CN118465272B (zh) * 2019-12-04 2025-08-19 珠海泰诺麦博制药股份有限公司 抗人巨细胞病毒抗体及其用途
TWI810589B (zh) 2020-06-21 2023-08-01 美商輝瑞股份有限公司 人巨細胞病毒糖蛋白B(gB)多肽
CN115947869B (zh) * 2022-11-28 2023-12-12 广州佰芮慷生物科技有限公司 一种靶向人巨细胞病毒的嵌合抗原受体、car-nk细胞及用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1445243A (zh) * 2002-12-13 2003-10-01 中国疾病控制中心病毒病预防控制所 抗人巨细胞病毒人源中和性基因工程Fab抗体
AU2004215125B2 (en) * 2003-02-26 2011-01-06 Institute For Research In Biomedicine Monoclonal antibody production by EBV transformation of B cells
WO2006124269A2 (en) * 2005-05-16 2006-11-23 Amgen Fremont Inc. Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders

Also Published As

Publication number Publication date
CA2672703C (en) 2016-11-22
US20100040602A1 (en) 2010-02-18
NO20092671L (no) 2009-09-03
AU2007331463B2 (en) 2014-03-27
ES2363992T3 (es) 2011-08-22
JP2010512736A (ja) 2010-04-30
BRPI0720464A2 (pt) 2014-01-14
EP2126049A1 (en) 2009-12-02
CN101627115B (zh) 2013-05-29
DE602007013618D1 (de) 2011-05-12
AU2007331463A1 (en) 2008-06-19
KR20090114364A (ko) 2009-11-03
JP5351041B2 (ja) 2013-11-27
EP2126049B1 (en) 2011-03-30
PT2126049E (pt) 2011-07-04
DK2126049T3 (da) 2011-07-18
IL199366A (en) 2015-03-31
EA200970586A1 (ru) 2009-12-30
EA018701B1 (ru) 2013-10-30
ATE503769T1 (de) 2011-04-15
US8153129B2 (en) 2012-04-10
WO2008071806A1 (en) 2008-06-19
CA2672703A1 (en) 2008-06-19
CN101627115A (zh) 2010-01-13

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