PL2115477T3 - Zastosowanie IGFBP-7 do oceny niewydolności serca - Google Patents
Zastosowanie IGFBP-7 do oceny niewydolności sercaInfo
- Publication number
- PL2115477T3 PL2115477T3 PL08707286T PL08707286T PL2115477T3 PL 2115477 T3 PL2115477 T3 PL 2115477T3 PL 08707286 T PL08707286 T PL 08707286T PL 08707286 T PL08707286 T PL 08707286T PL 2115477 T3 PL2115477 T3 PL 2115477T3
- Authority
- PL
- Poland
- Prior art keywords
- igfbp
- assessment
- heart failure
- heart
- failure
- Prior art date
Links
- 206010019280 Heart failures Diseases 0.000 title 1
- 108010008598 insulin-like growth factor binding protein-related protein 1 Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4727—Calcium binding proteins, e.g. calmodulin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4737—C-reactive protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4745—Insulin-like growth factor binding protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5412—IL-6
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07001582 | 2007-01-25 | ||
| EP08707286.4A EP2115477B1 (en) | 2007-01-25 | 2008-01-25 | Use of igfbp-7 in the assessment of heart failure |
| PCT/EP2008/000576 WO2008089994A1 (en) | 2007-01-25 | 2008-01-25 | Use of igfbp-7 in the assessment of heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2115477T3 true PL2115477T3 (pl) | 2015-12-31 |
Family
ID=37810309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08707286T PL2115477T3 (pl) | 2007-01-25 | 2008-01-25 | Zastosowanie IGFBP-7 do oceny niewydolności serca |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20100285491A1 (pl) |
| EP (2) | EP2498095A3 (pl) |
| JP (1) | JP2010517023A (pl) |
| CN (2) | CN101636656A (pl) |
| CA (1) | CA2671298C (pl) |
| DK (1) | DK2115477T3 (pl) |
| ES (1) | ES2548009T3 (pl) |
| HU (1) | HUE025408T2 (pl) |
| PL (1) | PL2115477T3 (pl) |
| WO (1) | WO2008089994A1 (pl) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2115477T3 (pl) * | 2007-01-25 | 2015-12-31 | Hoffmann La Roche | Zastosowanie IGFBP-7 do oceny niewydolności serca |
| US20120004133A1 (en) * | 2009-02-20 | 2012-01-05 | The Johns Hopkins University | Method for the diagnosis of age-associated vascular disorders |
| CA2769243C (en) | 2009-07-27 | 2017-08-22 | F. Hoffmann-La Roche Ag | Use of mimecan in the assessment of heart failure |
| CN102792161B (zh) * | 2009-08-28 | 2014-11-12 | 阿斯图特医药公司 | 肾损伤和肾衰竭的诊断及预后的方法及组合物 |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| DK2666872T3 (en) * | 2010-02-05 | 2016-07-25 | Astute Medical Inc | Methods and compositions for the diagnosis and prognosis of renal injury and renal insufficiency |
| JP5676763B2 (ja) | 2010-08-26 | 2015-02-25 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 動脈性高血圧症から心不全への初期移行の評価におけるバイオマーカーの使用 |
| FI20115367A0 (fi) * | 2011-04-15 | 2011-04-15 | Hytest Oy | Menetelmä sydän- ja verisuonitapahtumien määrittämiseksi käyttämällä IGFBP-fragmentteja |
| WO2013053076A1 (en) * | 2011-10-10 | 2013-04-18 | Zensun (Shanghai)Science & Technology Limited | Compositions and methods for treating heart failure |
| CN103998938B (zh) | 2011-10-17 | 2016-06-15 | 霍夫曼-拉罗奇有限公司 | 风险患者和中风原因的基于肌钙蛋白和bnp的诊断 |
| WO2013086359A1 (en) | 2011-12-08 | 2013-06-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP6298054B2 (ja) * | 2012-08-09 | 2018-03-20 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 心不全の診断 |
| EP4075143A1 (en) | 2012-09-12 | 2022-10-19 | Roche Diagnostics GmbH | Identification of patients with abnormal fractional shortening |
| EP2730923A1 (en) * | 2012-11-09 | 2014-05-14 | Roche Diagniostics GmbH | NTproBNP and cTnT based therapy guidance in heart failure |
| JP6342914B2 (ja) * | 2012-12-04 | 2018-06-13 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 心不全の治療選択におけるバイオマーカー |
| CA3158996C (en) | 2013-01-17 | 2024-06-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| HUE043373T2 (hu) * | 2013-06-06 | 2019-08-28 | Inst Nat Sante Rech Med | Szívelégtelenség utáni rehospitalizáció biomarkere |
| EP2843414B1 (en) * | 2013-08-26 | 2018-09-19 | Roche Diagniostics GmbH | Marker for statin treatment stratification in heart failure |
| MX375701B (es) * | 2013-11-06 | 2025-03-06 | Astute Medical Inc | Ensayos para igfbp7 con mejor rendimiento en muestras biológicas. |
| CN105917229B (zh) | 2013-12-03 | 2019-04-26 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| CN104758922A (zh) | 2014-01-03 | 2015-07-08 | 上海泽生科技开发有限公司 | 纽兰格林制剂的配方 |
| ES2712201T3 (es) | 2014-01-28 | 2019-05-09 | Hoffmann La Roche | Biomarcadores para la evaluación de riesgos y la monitorización del tratamiento en pacientes de insuficiencia cardíaca que han recibido terapia guiada por el péptido natriurético de tipo B |
| ES2939018T3 (es) | 2014-03-26 | 2023-04-18 | Hoffmann La Roche | IGFBP7 para diagnosticar una disfunción diastólica |
| CN103926401A (zh) * | 2014-03-31 | 2014-07-16 | 瑞莱生物科技(江苏)有限公司 | 一种快速定量检测igfbp-7和timp-2的免疫荧光试纸条及其制备方法 |
| CN105561298A (zh) | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
| EP4300104A3 (en) * | 2014-10-29 | 2024-09-25 | Roche Diagnostics GmbH | Biomarker for risk prediction of mortality |
| CN104408717A (zh) * | 2014-11-24 | 2015-03-11 | 北京航空航天大学 | 一种基于着色分离的病理图像颜色质量综合评价方法 |
| WO2016164854A1 (en) | 2015-04-09 | 2016-10-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP7080176B2 (ja) * | 2016-02-29 | 2022-06-03 | エフ.ホフマン-ラ ロシュ アーゲー | 子癇前症におけるマーカーとしてのigfbp-7 |
| AU2017277305A1 (en) | 2016-06-06 | 2018-12-20 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| EP3472622B1 (en) | 2016-06-17 | 2020-08-05 | Roche Diagnostics GmbH | Circulating angiopoietin-2 (ang-2) for the prediction of recurrence of atrial fibrillation |
| US10865412B2 (en) * | 2016-11-04 | 2020-12-15 | Ottawa Heart Institute Research | Therapeutics targeting IGFBP7 for the treatment or prevention of heart failure and metabolic diseases |
| ES2977423T3 (es) | 2017-12-13 | 2024-08-23 | Hoffmann La Roche | Angiopoyetina-2 (Ang-2) circulante y proteína de unión al factor de crecimiento insulínico 7 (IGFBP7) para la predicción de apoplejía |
| EP3824291A1 (en) | 2018-07-20 | 2021-05-26 | Roche Diagnostics GmbH | Prediction of preeclampsia based on igfbp-7 |
| KR20210044216A (ko) | 2018-08-10 | 2021-04-22 | 에프. 호프만-라 로슈 아게 | 심방세동-관련 뇌졸중 평가를 위한 ces-2 (카르복실에스테라제-2) |
| EP3837549A1 (en) | 2018-08-16 | 2021-06-23 | Roche Diagnostics GmbH | Circulating tfpi-2 (tissue factor pathway inhibitor 2) in the assessment of atrial fibrillation and anticoagulation therapy |
| JP7333384B2 (ja) | 2018-08-22 | 2023-08-24 | エフ. ホフマン-ラ ロシュ アーゲー | 心房細動の評価における循環spon-1(スポンジン-1) |
| KR20210049829A (ko) | 2018-08-24 | 2021-05-06 | 에프. 호프만-라 로슈 아게 | 심방 세동의 사정에서 및 뇌졸중의 예측을 위한 순환하는 fgfbp-1 (섬유모세포 성장 인자-결합 단백질 1) |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| EP3951387A4 (en) * | 2019-03-29 | 2022-11-23 | Eiken Kagaku Kabushiki Kaisha | MARKER FOR ARTERIOSCLEROSIS AND ARTERIOSCLEROSIS-RELATED DISEASE |
| CN120629587A (zh) | 2019-05-23 | 2025-09-12 | 豪夫迈·罗氏有限公司 | HFpEF的IGFBP7比率 |
| US20230314452A1 (en) | 2020-08-14 | 2023-10-05 | Roche Diagnostics Operations, Inc. | Igfbp7 for the assessment of silent brain infarcts and cognitive decline |
| CN115957301A (zh) * | 2021-10-13 | 2023-04-14 | 中国科学院上海营养与健康研究所 | 一种促进心梗心肌修复的细胞分泌因子及应用 |
| JP2025508481A (ja) | 2022-03-18 | 2025-03-26 | エフ. ホフマン-ラ ロシュ アーゲー | 2型対1型の急性心筋梗塞の早期識別のためのトロポニンマーカーの組合せ |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174A (en) | 1849-03-13 | Improvement in balances for weighing | ||
| US686A (en) | 1838-04-13 | Machine foe faking- and goring | ||
| DE3922873A1 (de) | 1989-04-25 | 1990-10-31 | Boehringer Mannheim Gmbh | Spezifische antikoerper gegen troponin t, ihre herstellung und verwendung in einem reagenz zur bestimmung von hermuskelnekrosen |
| US6333397B1 (en) | 1989-04-25 | 2001-12-25 | Roche Diagnostics Gmbh | Monoclonal antibodies to troponin T and their production |
| JPH07132095A (ja) | 1993-06-11 | 1995-05-23 | Nawata Arata | Dnaおよびそのコードする蛋白質 |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| DE69633780T3 (de) * | 1995-04-18 | 2011-05-05 | Biosite Incorporated, San Diego | Verfahren zum assay von troponin i und t und komplexen von troponin i und t und auswahl von antikörpern zur verwendung in immunoassays |
| WO2000035473A2 (en) * | 1998-12-18 | 2000-06-22 | Scios Inc. | Methods for detection and use of differentially expressed genes in disease states |
| WO2000036105A1 (en) | 1998-12-18 | 2000-06-22 | Human Genome Sciences, Inc. | Prostacyclin-stimulating factor-2 |
| US6709855B1 (en) * | 1998-12-18 | 2004-03-23 | Scios, Inc. | Methods for detection and use of differentially expressed genes in disease states |
| DK1141014T3 (da) * | 1999-01-06 | 2005-04-11 | Genentech Inc | Insulinlignende vækstfaktor (IGF) i mutantvariant |
| CN1327228C (zh) | 1999-01-29 | 2007-07-18 | 罗赫诊断器材股份有限公司 | 鉴定样品中的n-末端前bnp的方法 |
| EP1295939A4 (en) | 2000-06-15 | 2005-02-02 | Kyowa Hakko Kogyo Kk | INSULIN SIMILAR GROWTH FACTOR BINDING PROTEIN |
| US20030119009A1 (en) * | 2001-02-23 | 2003-06-26 | Stuart Susan G. | Genes regulated by MYCN activation |
| US7632647B2 (en) * | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
| US7713705B2 (en) * | 2002-12-24 | 2010-05-11 | Biosite, Inc. | Markers for differential diagnosis and methods of use thereof |
| DE60233301D1 (de) | 2001-05-04 | 2009-09-24 | Biosite Inc | Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs |
| GB0130557D0 (en) | 2001-12-20 | 2002-02-06 | Serono Internat S A | Proteins |
| WO2004042000A2 (en) | 2002-05-17 | 2004-05-21 | Human Genome Sciences, Inc. | 157 human secreted proteins |
| GB0216191D0 (en) * | 2002-07-11 | 2002-08-21 | Univ Leicester | Plasma urotensin in human heart failure |
| CN100497393C (zh) | 2003-05-12 | 2009-06-10 | 霍夫曼-拉罗奇有限公司 | 用结合脑钠尿肽前体分子氨基酸41-46的单克隆抗体检测脑钠尿肽前体分子的方法 |
| GB0329288D0 (en) * | 2003-12-18 | 2004-01-21 | Inverness Medical Switzerland | Monitoring method and apparatus |
| US20060003338A1 (en) | 2004-06-30 | 2006-01-05 | Deng David X | System and methods for the management and treatment of vascular graft disease |
| US7659091B2 (en) * | 2004-09-21 | 2010-02-09 | Nourheart, Inc. | Diagnostic marker |
| ITVI20050059A1 (it) | 2005-03-04 | 2006-09-05 | Consorzio Per Gli Studi Universitari In Verona | Nuovi biomarcatori per la diagnosi e/o la prognosi di neoplasie in animali |
| CN101185000A (zh) * | 2005-03-29 | 2008-05-21 | 因弗因斯医药瑞士股份有限公司 | 监测患者的方法和装置 |
| DE102005014752A1 (de) * | 2005-03-31 | 2006-11-23 | Johannes-Gutenberg-Universität Mainz | Entzündungsmarker und Kombinationen davon als biochemische Marker bei kardiovaskulären Erkrankungen |
| EP1722232A1 (en) * | 2005-05-09 | 2006-11-15 | F.Hoffmann-La Roche Ag | Devices and methods for diagnosing or predicting early stage cardiac dysfunctions |
| EP1731910A1 (en) * | 2005-06-07 | 2006-12-13 | F. Hoffmann-La Roche Ag | Use of NT-proANP and NT-proBNP for diagnosing cardiac diseases |
| EP2095107B1 (en) * | 2006-11-14 | 2014-07-02 | Alere San Diego, Inc. | Methods for risk assignment |
| PL2115477T3 (pl) * | 2007-01-25 | 2015-12-31 | Hoffmann La Roche | Zastosowanie IGFBP-7 do oceny niewydolności serca |
| ES2339284T3 (es) * | 2007-03-06 | 2010-05-18 | F. Hoffmann-La Roche Ag | Utilizacion de nogo-c en la deteccion de la insufuciencia cardiaca. |
| WO2008107201A1 (en) * | 2007-03-08 | 2008-09-12 | Roche Diagnostics Gmbh | Use of slim-1 in the assessment of heart failure |
| CA2769243C (en) * | 2009-07-27 | 2017-08-22 | F. Hoffmann-La Roche Ag | Use of mimecan in the assessment of heart failure |
-
2008
- 2008-01-25 PL PL08707286T patent/PL2115477T3/pl unknown
- 2008-01-25 EP EP12156343A patent/EP2498095A3/en not_active Withdrawn
- 2008-01-25 CA CA2671298A patent/CA2671298C/en active Active
- 2008-01-25 JP JP2009546687A patent/JP2010517023A/ja active Pending
- 2008-01-25 DK DK08707286.4T patent/DK2115477T3/en active
- 2008-01-25 CN CN200880003100A patent/CN101636656A/zh active Pending
- 2008-01-25 ES ES08707286.4T patent/ES2548009T3/es active Active
- 2008-01-25 WO PCT/EP2008/000576 patent/WO2008089994A1/en not_active Ceased
- 2008-01-25 CN CN201610893998.1A patent/CN106908603B/zh active Active
- 2008-01-25 EP EP08707286.4A patent/EP2115477B1/en active Active
- 2008-01-25 HU HUE08707286A patent/HUE025408T2/hu unknown
-
2009
- 2009-07-16 US US12/504,208 patent/US20100285491A1/en not_active Abandoned
-
2014
- 2014-11-13 US US14/540,165 patent/US20150293122A1/en not_active Abandoned
-
2016
- 2016-10-05 US US15/285,685 patent/US10488422B2/en active Active
-
2019
- 2019-10-10 US US16/598,361 patent/US10996229B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2548009T3 (es) | 2015-10-13 |
| US20170016918A1 (en) | 2017-01-19 |
| EP2498095A3 (en) | 2012-11-28 |
| EP2498095A2 (en) | 2012-09-12 |
| EP2115477A1 (en) | 2009-11-11 |
| DK2115477T3 (en) | 2015-08-10 |
| JP2010517023A (ja) | 2010-05-20 |
| US20150293122A1 (en) | 2015-10-15 |
| US20100285491A1 (en) | 2010-11-11 |
| WO2008089994A8 (en) | 2009-05-22 |
| HUE025408T2 (hu) | 2016-02-29 |
| CN106908603A (zh) | 2017-06-30 |
| US10996229B2 (en) | 2021-05-04 |
| US10488422B2 (en) | 2019-11-26 |
| CN101636656A (zh) | 2010-01-27 |
| CA2671298C (en) | 2020-07-28 |
| US20200064359A1 (en) | 2020-02-27 |
| CA2671298A1 (en) | 2008-07-31 |
| WO2008089994A1 (en) | 2008-07-31 |
| CN106908603B (zh) | 2019-04-02 |
| EP2115477B1 (en) | 2015-06-24 |
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