PL2187880T3 - Kompozycje i sposoby do leczenia zwyrodnienia plamki żółtej - Google Patents
Kompozycje i sposoby do leczenia zwyrodnienia plamki żółtejInfo
- Publication number
- PL2187880T3 PL2187880T3 PL08830106T PL08830106T PL2187880T3 PL 2187880 T3 PL2187880 T3 PL 2187880T3 PL 08830106 T PL08830106 T PL 08830106T PL 08830106 T PL08830106 T PL 08830106T PL 2187880 T3 PL2187880 T3 PL 2187880T3
- Authority
- PL
- Poland
- Prior art keywords
- compositions
- methods
- macular degeneration
- treating macular
- treating
- Prior art date
Links
- 208000002780 macular degeneration Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99337907P | 2007-09-12 | 2007-09-12 | |
| PCT/US2008/010676 WO2009035673A1 (en) | 2007-09-12 | 2008-09-12 | Compositions and methods for treating macular degeneration |
| EP08830106.4A EP2187880B1 (en) | 2007-09-12 | 2008-09-12 | Compositions and methods for treating macular degeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2187880T3 true PL2187880T3 (pl) | 2014-05-30 |
Family
ID=40452355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08830106T PL2187880T3 (pl) | 2007-09-12 | 2008-09-12 | Kompozycje i sposoby do leczenia zwyrodnienia plamki żółtej |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | USRE47045E1 (pl) |
| EP (2) | EP2687208A1 (pl) |
| JP (2) | JP5149388B2 (pl) |
| DK (1) | DK2187880T3 (pl) |
| ES (1) | ES2449150T3 (pl) |
| PL (1) | PL2187880T3 (pl) |
| PT (1) | PT2187880E (pl) |
| WO (1) | WO2009035673A1 (pl) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2327401A3 (en) | 2003-03-14 | 2011-10-19 | University of Washington | Retinoid Replacements and Opsin Agonists and Methods for the Use Thereof |
| JP5166026B2 (ja) | 2004-06-18 | 2013-03-21 | ユニバーシティ オブ ワシントン | 視力障害の治療のためのレチナール誘導体およびその使用方法 |
| USRE47045E1 (en) | 2007-09-12 | 2018-09-18 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating macular degeneration |
| JP6022746B2 (ja) | 2008-02-11 | 2016-11-09 | ユニヴァーシティ オブ ワシントン | 加齢関連性網膜機能不全の治療及び予防方法 |
| US20090312438A1 (en) * | 2008-06-13 | 2009-12-17 | Bernstein Paul S | Compositions and Methods for Attenuating the Formation of A2E in the Retinal Pigment Epithelium |
| JP5663025B2 (ja) | 2009-09-15 | 2015-02-04 | キューエルティー インコーポレイテッド | 9−cis−レチニルエステルを脂質ビヒクル中に含む医薬製剤 |
| CA2796991A1 (en) | 2010-04-19 | 2011-10-27 | Qlt Inc. | Therapeutic regimen and methods for treating or ameliorating visual disorders associated with an endogenous retinoid deficiency |
| MX370928B (es) | 2012-03-01 | 2020-01-08 | Retinagenix LLC | El uso de 9-cis-retinil acetato para mejorar la función visual de un sujeto que padece de pérdida de la función visual originada por una deficiencia retinoide endógena de 11-cis retinal. |
| EP2858648B1 (en) | 2012-06-07 | 2018-08-22 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the inhibition of pin1 |
| DK3855181T3 (da) | 2014-02-13 | 2025-02-10 | Katairo Gmbh | Forbindelser til behandling af lipofuscinrelaterede sygdomme |
| US20170112792A1 (en) * | 2014-03-21 | 2017-04-27 | Beth Israel Deaconess Medical Center, Inc. | Enhanced atra-related compounds derived from structure-activity relationships and modeling for inhibiting pin1 |
| WO2016011265A2 (en) | 2014-07-17 | 2016-01-21 | Beth Israel Deaconess Medical Center, Inc. | Biomarkers for pin1-associated disorders |
| KR102276424B1 (ko) * | 2014-10-06 | 2021-07-12 | 삼성전자주식회사 | 로-키나제 저해제를 포함하는 세포의 노화를 감소시키기 위한 조성물 및 그의 용도 |
| US9173915B1 (en) | 2014-10-10 | 2015-11-03 | Peter F. Kador | Antioxidant eye drops |
| WO2016145186A1 (en) | 2015-03-12 | 2016-09-15 | Beth Israel Deaconess Medical Center, Inc. | Enhanced atra-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions |
| WO2018112154A1 (en) * | 2016-12-15 | 2018-06-21 | Codiak Biosciences, Inc. | Methods of measuring exosomes using intrinsic fluorescence |
| CN118121573B (zh) * | 2022-12-01 | 2025-08-05 | 复旦大学 | 一种氘代维生素a及其衍生物的用途 |
| WO2024263751A2 (en) * | 2023-06-20 | 2024-12-26 | The Trustees Of Columbia University In The City Of New York | Novel co-drug, co-administration, and sequential administration of selective ttr ligand and c20-d3-retinol for elimination of mechanism-based ocular adverse effects in treating macular degeneration and ttr amyloidosis |
| WO2024263782A2 (en) * | 2023-06-20 | 2024-12-26 | The Trustees Of Columbia University In The City Of New York | Novel co-drug, co-administration, and sequential administration of bispecific rbp4/ttr ligand and c20-d3-retinol for elimination of mechanism-based ocular adverse effects in treating macular degeneration and ttr amyloidosis |
| WO2025147467A1 (en) | 2024-01-02 | 2025-07-10 | Alkeus Pharmaceuticals, Inc. | 10mg to 35mg of gildeuretinol for use in the treatment of stargardt disease |
| WO2025147228A1 (en) | 2024-01-02 | 2025-07-10 | Alkeus Pharmaceuticals, Inc. | Treatment for asymptomatic stargardt disease patients with gildeuretinol acetate |
| WO2025153898A1 (en) * | 2024-01-19 | 2025-07-24 | Gene Company Pty Ltd | Retinoid compositions and methods of use |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310764A (en) | 1992-05-08 | 1994-05-10 | Steven Baranowitz | Treatment of age related macular degeneration with beta-carotene |
| US5508456A (en) * | 1993-07-30 | 1996-04-16 | Ligand Pharmaceuticals Incorporated | 9-cis tritium-labeled retinoids and intermediates, methods for their synthesis and methods for their use in discovering retinoid X receptor ligands |
| US5489611A (en) | 1995-02-10 | 1996-02-06 | Warner-Lambert Company | Method for lowering plasma levels of lipoprotein (a) |
| US8198334B2 (en) | 1997-10-27 | 2012-06-12 | Pathologica Llc | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs |
| US6593104B1 (en) | 1999-02-12 | 2003-07-15 | University Of Iowa Research Foundation | Macular degeneration diagnostics and therapeutics |
| US20030149997A1 (en) | 1999-02-19 | 2003-08-07 | Hageman Gregory S. | Diagnostics and therapeutics for arterial wall disruptive disorders |
| JP2003507030A (ja) | 1999-08-16 | 2003-02-25 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 18個のヒト分泌タンパク質 |
| US20040009907A1 (en) | 2001-02-26 | 2004-01-15 | Alsobrook John P. | Proteins and nucleic acids encoding same |
| US20030032078A1 (en) | 2001-01-23 | 2003-02-13 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of macular and retinal degenerations |
| NZ516873A (en) | 2001-02-12 | 2003-11-28 | Warner Lambert Co | Compositions containing retinoids and erb inhibitors and their use in inhibiting retinoid skin damage |
| MXPA03008229A (es) | 2001-03-14 | 2004-11-12 | Lilly Co Eli | Trienos fluorados y su uso como moduladores rxr. |
| US6660297B2 (en) | 2001-03-23 | 2003-12-09 | Bausch & Lomb Incorporated | Nutritional supplement to treat macular degeneration |
| US20040121407A1 (en) | 2002-09-06 | 2004-06-24 | Elixir Pharmaceuticals, Inc. | Regulation of the growth hormone/IGF-1 axis |
| EP1567198A4 (en) | 2002-12-02 | 2006-05-31 | Genvec Inc | MATERIALS AND METHOD FOR THE TREATMENT OF EYE DISEASES |
| EP1628631A2 (en) | 2003-06-05 | 2006-03-01 | Achkar, Charles C. | Methods of treating hyperproliferative cell disorders |
| US7842722B2 (en) | 2003-12-19 | 2010-11-30 | Alcon, Inc. | Composition and methods for inhibiting the progression macular degeneration and promoting healthy vision |
| FR2864871A1 (fr) | 2004-01-06 | 2005-07-08 | Thomson Licensing Sa | Methode de decouverte d'un reseau domestique et appareil implementant la methode |
| US7309487B2 (en) | 2004-02-09 | 2007-12-18 | George Inana | Methods and compositions for detecting and treating retinal diseases |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| CA2601278C (en) * | 2004-03-17 | 2014-06-10 | Lars Michael Larsen | Prevention of retinopathy by inhibition of the visual cycle |
| US20060089411A1 (en) | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
| WO2006033734A2 (en) * | 2004-08-18 | 2006-03-30 | Sirion Therapeutics, Inc. | Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders |
| WO2006047475A2 (en) | 2004-10-25 | 2006-05-04 | Sytera, Inc. | Detection and analysis of ophthalmically-relevant fluorescent molecules |
| WO2006052860A2 (en) | 2004-11-04 | 2006-05-18 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (rbp)-transthyretin (ttr) complex formation |
| SG144145A1 (en) | 2004-12-08 | 2008-07-29 | Sirion Therapeutics Inc | Methods, assays and compositions for treating retinol-related diseases |
| US20070014833A1 (en) | 2005-03-30 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| US20060292099A1 (en) | 2005-05-25 | 2006-12-28 | Michael Milburn | Treatment of eye disorders with sirtuin modulators |
| BRPI0610308A8 (pt) | 2005-05-26 | 2017-04-25 | Neuron Systems Inc | Composições e métodos para o tratamento de doença retinal |
| UA81382C2 (en) | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
| WO2007037188A1 (ja) * | 2005-09-27 | 2007-04-05 | Sapporo Medical University | 血管透過性亢進に起因する眼疾患の予防及び治療のための医薬 |
| USRE47045E1 (en) | 2007-09-12 | 2018-09-18 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating macular degeneration |
| US8263601B2 (en) | 2009-02-27 | 2012-09-11 | Concert Pharmaceuticals, Inc. | Deuterium substituted xanthine derivatives |
| EP3090999A1 (en) | 2009-06-18 | 2016-11-09 | Concert Pharmaceuticals Inc. | Deuterated isoindoline-1, 3-dione derivatives as pde4 and tnf-alpha inhibitors |
| WO2012057723A1 (en) | 2009-10-22 | 2012-05-03 | Proksch, Roger | Thermal measurements using multiple frequency atomic force microscopy |
-
2008
- 2008-09-12 US US15/343,016 patent/USRE47045E1/en active Active
- 2008-09-12 EP EP13186626.1A patent/EP2687208A1/en active Pending
- 2008-09-12 JP JP2010524874A patent/JP5149388B2/ja active Active
- 2008-09-12 EP EP08830106.4A patent/EP2187880B1/en active Active
- 2008-09-12 PT PT88301064T patent/PT2187880E/pt unknown
- 2008-09-12 US US12/733,631 patent/US8877809B2/en not_active Ceased
- 2008-09-12 ES ES08830106.4T patent/ES2449150T3/es active Active
- 2008-09-12 WO PCT/US2008/010676 patent/WO2009035673A1/en not_active Ceased
- 2008-09-12 DK DK08830106.4T patent/DK2187880T3/da active
- 2008-09-12 PL PL08830106T patent/PL2187880T3/pl unknown
-
2012
- 2012-11-29 JP JP2012260971A patent/JP5695017B2/ja active Active
-
2014
- 2014-10-09 US US14/510,975 patent/US9486432B2/en active Active
-
2016
- 2016-11-04 US US15/344,102 patent/US20170128403A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2187880B1 (en) | 2013-12-18 |
| JP5149388B2 (ja) | 2013-02-20 |
| DK2187880T3 (da) | 2014-03-10 |
| US8877809B2 (en) | 2014-11-04 |
| ES2449150T3 (es) | 2014-03-18 |
| US20110034554A1 (en) | 2011-02-10 |
| EP2187880A1 (en) | 2010-05-26 |
| WO2009035673A8 (en) | 2009-07-02 |
| EP2687208A1 (en) | 2014-01-22 |
| JP5695017B2 (ja) | 2015-04-01 |
| USRE47045E1 (en) | 2018-09-18 |
| EP2187880A4 (en) | 2010-09-08 |
| US9486432B2 (en) | 2016-11-08 |
| US20150133549A1 (en) | 2015-05-14 |
| PT2187880E (pt) | 2014-03-25 |
| US20170128403A1 (en) | 2017-05-11 |
| WO2009035673A1 (en) | 2009-03-19 |
| JP2010539168A (ja) | 2010-12-16 |
| JP2013049711A (ja) | 2013-03-14 |
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