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PL2064337T3 - Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznych - Google Patents

Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznych

Info

Publication number
PL2064337T3
PL2064337T3 PL07838397T PL07838397T PL2064337T3 PL 2064337 T3 PL2064337 T3 PL 2064337T3 PL 07838397 T PL07838397 T PL 07838397T PL 07838397 T PL07838397 T PL 07838397T PL 2064337 T3 PL2064337 T3 PL 2064337T3
Authority
PL
Poland
Prior art keywords
facs
based system
high throughput
therapeutic proteins
reporter protein
Prior art date
Application number
PL07838397T
Other languages
English (en)
Inventor
Christine Demaria
Scott Estes
Kenneth P Karey
Victor Cairns
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of PL2064337T3 publication Critical patent/PL2064337T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1086Preparation or screening of expression libraries, e.g. reporter assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70592CD52
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PL07838397T 2006-09-20 2007-09-18 Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznych PL2064337T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84622306P 2006-09-20 2006-09-20
US84770506P 2006-09-27 2006-09-27
EP07838397A EP2064337B1 (en) 2006-09-20 2007-09-18 A facs-and reporter protein-based system for high throughput development of therapeutic proteins
PCT/US2007/020180 WO2008036255A2 (en) 2006-09-20 2007-09-18 A facs-and reporter protein-based system for high throughput development of therapeutic proteins

Publications (1)

Publication Number Publication Date
PL2064337T3 true PL2064337T3 (pl) 2012-12-31

Family

ID=39201056

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07838397T PL2064337T3 (pl) 2006-09-20 2007-09-18 Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznych

Country Status (7)

Country Link
US (1) US20090239235A1 (pl)
EP (1) EP2064337B1 (pl)
AR (1) AR062916A1 (pl)
ES (1) ES2388003T3 (pl)
PL (1) PL2064337T3 (pl)
PT (1) PT2064337E (pl)
WO (1) WO2008036255A2 (pl)

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EP2404869A1 (en) * 2010-07-06 2012-01-11 Ammonia Casale S.A. Process for producing ammonia synthesis gas
JP2013542838A (ja) 2010-11-16 2013-11-28 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー ドライアイを治療するためのシステムおよび方法
US9821159B2 (en) 2010-11-16 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Stimulation devices and methods
US9717627B2 (en) 2013-03-12 2017-08-01 Oculeve, Inc. Implant delivery devices, systems, and methods
AU2014253754C1 (en) 2013-04-19 2015-07-30 Oculeve, Inc. Nasal stimulation devices and methods
CN111298285A (zh) 2014-02-25 2020-06-19 奥库利维公司 用于鼻泪刺激的聚合物制剂
EP3171928B1 (en) 2014-07-25 2020-02-26 Oculeve, Inc. Stimulation patterns for treating dry eye
CA2965514A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Contact lens for increasing tear production
MX2017005204A (es) 2014-10-22 2017-12-14 Oculeve Inc Dispositivos y métodos de estimulación para tratar el ojo seco.
JP6810052B2 (ja) 2015-03-27 2021-01-06 スリーエム イノベイティブ プロパティズ カンパニー フィブリン組成物、方法及び創傷物品
IL258538B2 (en) 2015-10-09 2023-04-01 Genzyme Corp Early isolation after the infection of cells (epic) for the production of biological material
US10426958B2 (en) 2015-12-04 2019-10-01 Oculeve, Inc. Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
US10252048B2 (en) 2016-02-19 2019-04-09 Oculeve, Inc. Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
EP3452166A4 (en) 2016-05-02 2019-12-18 Oculeve, Inc. INTRANASAL STIMULATION FOR THE TREATMENT OF DISEASES OF MEIBOM'S GLANDS AND BLEPHARITIS
EP3522942B1 (en) 2016-10-05 2023-12-27 3M Innovative Properties Company Fibrin composition comprising carrier material, method and wound articles
WO2018067622A1 (en) 2016-10-05 2018-04-12 3M Innovative Properties Company Fibrinogen composition, method and wound articles
PL3523440T3 (pl) 2016-10-07 2025-06-09 Genzyme Corporation Wczesna izolacja komórek po transfekcji (epic) do wytwarzania środków biologicznych
RU2019118600A (ru) 2016-12-02 2021-01-11 Окулив, Инк. Аппарат и способ составления прогноза синдрома сухого глаза и рекомендаций по лечению
IL302786A (en) 2020-11-19 2023-07-01 Genzyme Corp Flow cytometry attenuated reporter expression (flare) multiple reporter system and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937190A (en) * 1987-10-15 1990-06-26 Wisconsin Alumni Research Foundation Translation enhancer
US6653132B1 (en) * 1997-02-25 2003-11-25 Qbi Enterprises, Ltd. IRES sequences with high translational efficiency and expression vectors containing the sequence
GB9815909D0 (en) * 1998-07-21 1998-09-16 Btg Int Ltd Antibody preparation
WO2001057212A1 (en) * 2000-02-02 2001-08-09 Iconix Pharmaceuticals, Inc. Rapid, parallel identification of cell lines
WO2002070710A1 (en) * 2001-03-01 2002-09-12 University Of California Method to identify ires elements
DE10143238A1 (de) * 2001-09-04 2003-03-20 Icon Genetics Ag Identifizierung eukaryotischer interner Ribosomen-Eingangsstellen (IRES)-Elemente
DE10143237A1 (de) * 2001-09-04 2003-03-20 Icon Genetics Ag Herstellung künstlicher interner ribosomaler Eingangsstellenelemente (Ires-Elemente)
US7119187B2 (en) * 2002-07-09 2006-10-10 National Health Research Institutes Internal ribosome entry site of the labial gene for protein expression
CN101942442B (zh) * 2003-06-24 2013-10-09 建新公司 新的β-肌动蛋白和RPS21启动子及其应用
CN101090968B (zh) * 2004-11-08 2011-10-26 科罗迈吉尼科斯公司 高水平表达蛋白质的宿主细胞的选择
KR101271884B1 (ko) * 2004-11-08 2013-06-05 크로마제닉스 비.브이. 고수준으로 단백질을 발현하는 숙주세포의 선택

Also Published As

Publication number Publication date
ES2388003T3 (es) 2012-10-05
EP2064337A2 (en) 2009-06-03
US20090239235A1 (en) 2009-09-24
WO2008036255A2 (en) 2008-03-27
WO2008036255A3 (en) 2008-07-24
EP2064337B1 (en) 2012-07-18
PT2064337E (pt) 2012-07-26
AR062916A1 (es) 2008-12-17

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