PL1897867T3 - Związki stosowane do przerywania wychwytu zwrotnego 5-hydroksytryptaminy i norepinefryny lub leczenia chorób, takich jak depresja - Google Patents
Związki stosowane do przerywania wychwytu zwrotnego 5-hydroksytryptaminy i norepinefryny lub leczenia chorób, takich jak depresjaInfo
- Publication number
- PL1897867T3 PL1897867T3 PL06752979T PL06752979T PL1897867T3 PL 1897867 T3 PL1897867 T3 PL 1897867T3 PL 06752979 T PL06752979 T PL 06752979T PL 06752979 T PL06752979 T PL 06752979T PL 1897867 T3 PL1897867 T3 PL 1897867T3
- Authority
- PL
- Poland
- Prior art keywords
- hydroxytryptamine
- reuptake
- norepinephrine
- interrupting
- depression
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title 2
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229960002748 norepinephrine Drugs 0.000 title 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200510077510 | 2005-06-17 | ||
| CN2006100733084A CN1955159B (zh) | 2005-06-17 | 2006-04-07 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1897867T3 true PL1897867T3 (pl) | 2017-09-29 |
Family
ID=37531963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06752979T PL1897867T3 (pl) | 2005-06-17 | 2006-06-16 | Związki stosowane do przerywania wychwytu zwrotnego 5-hydroksytryptaminy i norepinefryny lub leczenia chorób, takich jak depresja |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8178724B2 (pl) |
| EP (1) | EP1897867B8 (pl) |
| JP (1) | JP5080458B2 (pl) |
| KR (1) | KR101304505B1 (pl) |
| CN (1) | CN1955159B (pl) |
| AU (1) | AU2006257558B9 (pl) |
| CA (1) | CA2612413C (pl) |
| DK (1) | DK1897867T3 (pl) |
| ES (1) | ES2624789T3 (pl) |
| PL (1) | PL1897867T3 (pl) |
| PT (1) | PT1897867T (pl) |
| RU (1) | RU2416598C2 (pl) |
| WO (1) | WO2006133652A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1955159B (zh) * | 2005-06-17 | 2010-11-24 | 山东绿叶制药有限公司 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
| WO2012041013A1 (en) * | 2010-10-01 | 2012-04-05 | Shan Dong Luye Pharmaceutical Co., Ltd. | Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same |
| CN102871997B (zh) * | 2011-07-12 | 2013-11-13 | 山东绿叶制药有限公司 | 含有去甲基文拉法辛苯甲酸酯类化合物的缓释药物组合物 |
| CN104127401A (zh) * | 2013-08-28 | 2014-11-05 | 山东绿叶制药有限公司 | 含有去甲基文拉法辛苯甲酸酯类化合物的渗透泵控释组合物 |
| CN103570669B (zh) * | 2013-10-31 | 2015-07-22 | 吉林大学 | 脑靶向o-去甲基文拉法辛酚酯类前药及制备方法和用途 |
| CN104666291A (zh) * | 2013-11-26 | 2015-06-03 | 山东绿叶制药有限公司 | 去甲基文拉法辛苯甲酸酯类化合物在制备改善性功能障碍药物中的应用 |
| CN104672097B (zh) * | 2013-12-03 | 2016-06-29 | 山东绿叶制药有限公司 | 化合物对甲基苯甲酸4-（2-二甲胺基-1-环己烯基乙基）苯酯制备方法及应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| US5530013A (en) * | 1994-02-14 | 1996-06-25 | American Home Products Corporation | Venlafaxine in the inducement of cognition enhancement |
| DE19525137C2 (de) * | 1995-07-11 | 2003-02-27 | Gruenenthal Gmbh | 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe |
| US20020022662A1 (en) | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
| US7291646B2 (en) | 1999-11-24 | 2007-11-06 | Wyeth | Ethers of O-desmethyl venlafaxine |
| US6348494B1 (en) * | 2000-11-21 | 2002-02-19 | American Home Products Corporation | Ethers of o-desmethyl venlafaxine |
| ATE369330T1 (de) * | 2001-02-12 | 2007-08-15 | Wyeth Corp | O-desmethyl-venlafaxine succinat salz |
| WO2003042162A1 (en) * | 2001-11-17 | 2003-05-22 | Neurosearch A/S | Prodrugs of antidepressants and their use for treating depressions |
| AU2003226752A1 (en) | 2002-03-28 | 2003-10-13 | Synthon B.V. | Venlafaxine base |
| TWI306092B (en) | 2003-03-11 | 2009-02-11 | Wyeth Corp | Process for preparation of phenethylamine derivatives |
| CN100455560C (zh) * | 2004-06-09 | 2009-01-28 | 中国人民解放军军事医学科学院放射医学研究所 | 含长链脂肪酰基取代的文拉法辛前体药物及其制备方法和用途 |
| CN1955159B (zh) * | 2005-06-17 | 2010-11-24 | 山东绿叶制药有限公司 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
-
2006
- 2006-04-07 CN CN2006100733084A patent/CN1955159B/zh active Active
- 2006-06-16 EP EP06752979.2A patent/EP1897867B8/en active Active
- 2006-06-16 CA CA2612413A patent/CA2612413C/en active Active
- 2006-06-16 KR KR1020087001286A patent/KR101304505B1/ko active Active
- 2006-06-16 WO PCT/CN2006/001370 patent/WO2006133652A1/zh not_active Ceased
- 2006-06-16 JP JP2008516114A patent/JP5080458B2/ja active Active
- 2006-06-16 PT PT67529792T patent/PT1897867T/pt unknown
- 2006-06-16 PL PL06752979T patent/PL1897867T3/pl unknown
- 2006-06-16 RU RU2008101776/04A patent/RU2416598C2/ru active
- 2006-06-16 AU AU2006257558A patent/AU2006257558B9/en active Active
- 2006-06-16 US US11/917,905 patent/US8178724B2/en active Active
- 2006-06-16 DK DK06752979.2T patent/DK1897867T3/en active
- 2006-06-16 ES ES06752979.2T patent/ES2624789T3/es active Active
-
2012
- 2012-04-05 US US13/440,608 patent/US8487132B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080042068A (ko) | 2008-05-14 |
| US8487132B2 (en) | 2013-07-16 |
| CN1955159B (zh) | 2010-11-24 |
| PT1897867T (pt) | 2017-05-22 |
| EP1897867B1 (en) | 2017-02-15 |
| CA2612413C (en) | 2013-03-12 |
| US8178724B2 (en) | 2012-05-15 |
| US20120190741A1 (en) | 2012-07-26 |
| AU2006257558B2 (en) | 2012-01-12 |
| AU2006257558B8 (en) | 2012-02-02 |
| AU2006257558B9 (en) | 2012-02-02 |
| CA2612413A1 (en) | 2006-12-21 |
| JP2008543794A (ja) | 2008-12-04 |
| US20090118368A1 (en) | 2009-05-07 |
| AU2006257558A1 (en) | 2006-12-21 |
| JP5080458B2 (ja) | 2012-11-21 |
| KR101304505B1 (ko) | 2013-09-05 |
| EP1897867B8 (en) | 2017-08-23 |
| EP1897867A1 (en) | 2008-03-12 |
| WO2006133652A1 (en) | 2006-12-21 |
| EP1897867A4 (en) | 2010-09-29 |
| ES2624789T3 (es) | 2017-07-17 |
| RU2416598C2 (ru) | 2011-04-20 |
| RU2008101776A (ru) | 2009-11-27 |
| DK1897867T3 (en) | 2017-05-15 |
| CN1955159A (zh) | 2007-05-02 |
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