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PL1873158T3 - Kryształy pochodnej morfinanu i sposoby ich wytwarzania - Google Patents

Kryształy pochodnej morfinanu i sposoby ich wytwarzania

Info

Publication number
PL1873158T3
PL1873158T3 PL06731279.3T PL06731279T PL1873158T3 PL 1873158 T3 PL1873158 T3 PL 1873158T3 PL 06731279 T PL06731279 T PL 06731279T PL 1873158 T3 PL1873158 T3 PL 1873158T3
Authority
PL
Poland
Prior art keywords
crystals
producing
same
morphinan derivative
morphinan
Prior art date
Application number
PL06731279.3T
Other languages
English (en)
Inventor
Hisanori Wakita
Masahiro Akimoto
Takahiro Takeda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL1873158T3 publication Critical patent/PL1873158T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
PL06731279.3T 2005-04-06 2006-04-06 Kryształy pochodnej morfinanu i sposoby ich wytwarzania PL1873158T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2005110096 2005-04-06

Publications (1)

Publication Number Publication Date
PL1873158T3 true PL1873158T3 (pl) 2016-09-30

Family

ID=37086947

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06731279.3T PL1873158T3 (pl) 2005-04-06 2006-04-06 Kryształy pochodnej morfinanu i sposoby ich wytwarzania

Country Status (16)

Country Link
US (1) US7803942B2 (pl)
EP (1) EP1873158B1 (pl)
JP (1) JP5076498B2 (pl)
KR (1) KR101333620B1 (pl)
CN (1) CN101155814B (pl)
AU (1) AU2006234257B2 (pl)
BR (1) BRPI0608671B1 (pl)
CA (1) CA2602968C (pl)
DK (1) DK1873158T3 (pl)
ES (1) ES2568475T3 (pl)
HU (1) HUE029202T2 (pl)
NO (1) NO339927B1 (pl)
NZ (1) NZ563133A (pl)
PL (1) PL1873158T3 (pl)
RU (1) RU2397173C2 (pl)
WO (1) WO2006109671A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563727B2 (en) * 2009-02-23 2013-10-22 Mallinckrodt Llc (+)-morphinanium N-oxides and processes for their production
WO2010096791A1 (en) * 2009-02-23 2010-08-26 Mallinckrodt Inc. (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
CN102325776A (zh) * 2009-02-23 2012-01-18 马林克罗特公司 (+)-吗啡喃*季盐及其制备方法
US8946419B2 (en) 2009-02-23 2015-02-03 Mallinckrodt Llc (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
US8420819B2 (en) * 2009-06-03 2013-04-16 Boehringer Ingelheim International Gmbh Process for optimizing the particle size of an active pharmaceutical ingredient by crystallization
US8829020B2 (en) 2009-07-16 2014-09-09 Mallinckrodt Llc Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
AU2012304484B2 (en) 2011-09-08 2016-07-28 SpecGx LLC Production of alkaloids without the isolation of intermediates
TWI449704B (zh) * 2013-04-26 2014-08-21 Everlight Chem Ind Corp 嗎啡喃衍生物之結晶、其製造方法、及使用其之醫藥組成物
CN106866688B (zh) * 2015-12-10 2019-05-03 山东诚创医药技术开发有限公司 一种纳呋拉啡的精制方法
US20210015813A1 (en) 2018-03-08 2021-01-21 Victoria Link Ltd. Treatment of demyelinating diseases
CN115181109B (zh) * 2021-04-02 2024-06-04 南京正大天晴制药有限公司 吗啡喃衍生物的晶体及其制备方法
CN115960108A (zh) * 2021-10-09 2023-04-14 山东新时代药业有限公司 一种无定型盐酸纳呋拉啡及其制备方法
CN114736210A (zh) * 2022-03-29 2022-07-12 伊诺药物研究(南京)有限公司 吗啡喃衍生物的一种晶型的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4110116C2 (de) * 1991-03-27 1996-06-13 Thermodach Dachtechnik Gmbh Energiespeichernde Wärmedämmplatte
EP0846694A1 (en) * 1992-01-23 1998-06-10 Toray Industries, Inc. Morphinan derivative and its pharmaceutical applications
WO1995001178A1 (en) 1993-06-30 1995-01-12 Toray Industries, Inc. Antitussive
CA2144770C (en) 1993-07-19 2006-02-28 Hiroshi Nagase Brain cell protective agent
NZ268969A (en) 1993-07-23 1997-06-24 Toray Industries Morphinan derivatives and pharmaceutical compositions
US5869669A (en) * 1996-07-26 1999-02-09 Penick Corporation Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates
ES2215158T3 (es) * 1996-11-25 2004-10-01 Toray Industries, Inc. Agente antipruritico.

Also Published As

Publication number Publication date
KR20080004500A (ko) 2008-01-09
EP1873158A4 (en) 2010-06-02
CA2602968C (en) 2014-09-23
NO339927B1 (no) 2017-02-13
ES2568475T3 (es) 2016-04-29
BRPI0608671A2 (pt) 2010-01-19
US7803942B2 (en) 2010-09-28
BRPI0608671B1 (pt) 2022-07-19
DK1873158T3 (en) 2016-06-27
JPWO2006109671A1 (ja) 2008-11-13
RU2007140890A (ru) 2009-05-20
RU2397173C2 (ru) 2010-08-20
AU2006234257B2 (en) 2011-03-10
NZ563133A (en) 2010-07-30
AU2006234257A1 (en) 2006-10-19
CA2602968A1 (en) 2006-10-19
CN101155814A (zh) 2008-04-02
CN101155814B (zh) 2010-06-16
HUE029202T2 (en) 2017-02-28
EP1873158A1 (en) 2008-01-02
WO2006109671A1 (ja) 2006-10-19
JP5076498B2 (ja) 2012-11-21
US20090062544A1 (en) 2009-03-05
NO20075557L (no) 2007-11-02
KR101333620B1 (ko) 2013-11-27
EP1873158B1 (en) 2016-04-06

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