PL1846371T3 - Sposób otrzymywania chlorku [1,4']-bipiperydynylo-1'-karbonylu lub jego chlorowodorku - Google Patents
Sposób otrzymywania chlorku [1,4']-bipiperydynylo-1'-karbonylu lub jego chlorowodorkuInfo
- Publication number
- PL1846371T3 PL1846371T3 PL06708891T PL06708891T PL1846371T3 PL 1846371 T3 PL1846371 T3 PL 1846371T3 PL 06708891 T PL06708891 T PL 06708891T PL 06708891 T PL06708891 T PL 06708891T PL 1846371 T3 PL1846371 T3 PL 1846371T3
- Authority
- PL
- Poland
- Prior art keywords
- bipiperidinyl
- hydrochloride
- producing
- carbonyl chloride
- carbonyl
- Prior art date
Links
- YDNSNQRKIINKPV-UHFFFAOYSA-N 4-piperidin-1-ylpiperidine-1-carbonyl chloride Chemical compound C1CN(C(=O)Cl)CCC1N1CCCCC1 YDNSNQRKIINKPV-UHFFFAOYSA-N 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65053505P | 2005-02-08 | 2005-02-08 | |
| PCT/FI2006/000032 WO2006084940A1 (en) | 2005-02-08 | 2006-02-06 | Process for producing [1,4'] bipiperidinyl-1'-carbonyl chloride or hydrochloride thereof |
| EP06708891.4A EP1846371B1 (en) | 2005-02-08 | 2006-02-06 | Process for producing [1,4']bipiperidinyl-1'-carbonyl chloride or hydrochloride thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1846371T3 true PL1846371T3 (pl) | 2014-01-31 |
Family
ID=36585252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06708891T PL1846371T3 (pl) | 2005-02-08 | 2006-02-06 | Sposób otrzymywania chlorku [1,4']-bipiperydynylo-1'-karbonylu lub jego chlorowodorku |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7662964B2 (pl) |
| EP (1) | EP1846371B1 (pl) |
| JP (1) | JP5133703B2 (pl) |
| CA (1) | CA2591071C (pl) |
| ES (1) | ES2430375T3 (pl) |
| PL (1) | PL1846371T3 (pl) |
| WO (1) | WO2006084940A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8546573B2 (en) * | 2009-11-18 | 2013-10-01 | Cadila Healthcare Limited | Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate |
| CN102627653B (zh) * | 2012-03-20 | 2014-10-29 | 南京臣功制药股份有限公司 | 盐酸伊立替康的制备方法 |
| KR101327720B1 (ko) * | 2013-02-15 | 2013-11-11 | 제일약품주식회사 | 이리노테칸의 제조방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4473692A (en) | 1981-09-04 | 1984-09-25 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
| JPS6019790A (ja) * | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| US4894456A (en) | 1987-03-31 | 1990-01-16 | Research Triangle Institute | Synthesis of camptothecin and analogs thereof |
| US5053512A (en) | 1987-04-14 | 1991-10-01 | Research Triangle Institute | Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives |
| IL117684A (en) | 1995-04-07 | 2002-02-10 | Pharmacia & Upjohn Inc | Intermediates and Process for Production of History of Kempotocin (CPT-11) and Related Compounds |
| JP3046258B2 (ja) * | 1997-04-11 | 2000-05-29 | 株式会社ヤクルト本社 | １−クロロカルボニル−４−ピペリジノピペリジンまたはその塩酸塩の製造方法 |
| US6476043B1 (en) | 1998-08-05 | 2002-11-05 | Aventis Pharma S.A. | Use of camptothecin derivatives, with reduced gastrointestinal toxicity |
| TWI245768B (en) | 2001-02-21 | 2005-12-21 | Yakult Honsha Kk | Process for synthesizing camptothecin related compound(s) |
| JP4986343B2 (ja) * | 2001-06-19 | 2012-07-25 | 保土谷化学工業株式会社 | １−クロロカルボニルピペリジン誘導体塩酸塩の処理方法 |
| CN1276923C (zh) | 2002-03-01 | 2006-09-27 | 法玛西雅意大利公司 | 盐酸伊立替康的结晶多晶型物 |
| WO2003089413A1 (en) | 2002-04-17 | 2003-10-30 | Pharmacia Corporation | Pharmacia corporation |
| US20050267141A1 (en) | 2004-05-28 | 2005-12-01 | Phytogen Life Sciences Inc. | Process to prepare camptothecin derivatives |
| JP2008509211A (ja) | 2004-08-09 | 2008-03-27 | シルパ・メディケア・リミテッド | 塩酸イリノテカン三水和物の改良された製造方法 |
| DE602006009901D1 (de) | 2005-02-07 | 2009-12-03 | Fermion Oy | Verfahren zur herstellung von 7-ethyl-10-hydroxycamptothecin |
-
2006
- 2006-02-06 ES ES06708891T patent/ES2430375T3/es active Active
- 2006-02-06 JP JP2007553632A patent/JP5133703B2/ja not_active Expired - Fee Related
- 2006-02-06 WO PCT/FI2006/000032 patent/WO2006084940A1/en not_active Ceased
- 2006-02-06 CA CA2591071A patent/CA2591071C/en not_active Expired - Fee Related
- 2006-02-06 PL PL06708891T patent/PL1846371T3/pl unknown
- 2006-02-06 US US11/883,578 patent/US7662964B2/en not_active Expired - Fee Related
- 2006-02-06 EP EP06708891.4A patent/EP1846371B1/en not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| US7662964B2 (en) | 2010-02-16 |
| ES2430375T3 (es) | 2013-11-20 |
| CA2591071C (en) | 2014-04-29 |
| EP1846371B1 (en) | 2013-07-31 |
| JP5133703B2 (ja) | 2013-01-30 |
| US20080161571A1 (en) | 2008-07-03 |
| JP2008529991A (ja) | 2008-08-07 |
| CA2591071A1 (en) | 2006-08-17 |
| WO2006084940A1 (en) | 2006-08-17 |
| EP1846371A1 (en) | 2007-10-24 |
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