PL1740154T3 - Kompozycje insuliny o ulepszonym wchłanianiu - Google Patents

Kompozycje insuliny o ulepszonym wchłanianiu

Info

Publication number: PL1740154T3
Authority: PL; Poland
Prior art keywords: formulations; acid; drug; improved absorption; insulin compositions
Prior art date: 2004-03-12

Application number

PL05728268T

Other languages

English (en)

Inventor

Roderike Pohl

Solomon S Steiner

Original Assignee

Biodel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-03-12

Filing date

2005-03-11

Publication date

2009-11-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34963134&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1740154(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-03-11 Application filed by Biodel Inc filed Critical Biodel Inc

2009-11-30 Publication of PL1740154T3 publication Critical patent/PL1740154T3/pl

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 4
239000000203 mixture Substances 0.000 title abstract 3
102000004877 Insulin Human genes 0.000 title abstract 2
108090001061 Insulin Proteins 0.000 title abstract 2
229940125396 insulin Drugs 0.000 title abstract 2
238000010521 absorption reaction Methods 0.000 title 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
238000009472 formulation Methods 0.000 abstract 2
239000000546 pharmaceutical excipient Substances 0.000 abstract 2
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
229960005070 ascorbic acid Drugs 0.000 abstract 1
235000010323 ascorbic acid Nutrition 0.000 abstract 1
239000011668 ascorbic acid Substances 0.000 abstract 1
239000002738 chelating agent Substances 0.000 abstract 1
238000004090 dissolution Methods 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
238000012377 drug delivery Methods 0.000 abstract 1
239000013583 drug formulation Substances 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
229910052751 metal Inorganic materials 0.000 abstract 1
230000003381 solubilizing effect Effects 0.000 abstract 1
238000010254 subcutaneous injection Methods 0.000 abstract 1
239000007929 subcutaneous injection Substances 0.000 abstract 1
230000009885 systemic effect Effects 0.000 abstract 1
229910052725 zinc Inorganic materials 0.000 abstract 1
239000011701 zinc Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Zoology (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Obesity (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL05728268T 2004-03-12 2005-03-11 Kompozycje insuliny o ulepszonym wchłanianiu PL1740154T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US55263704P	2004-03-12	2004-03-12
US60919404P	2004-09-09	2004-09-09
EP05728268A EP1740154B1 (en)	2004-03-12	2005-03-11	Insulin compositions with improved absorption
PCT/US2005/008187 WO2005089722A1 (en)	2004-03-12	2005-03-11	Rapid acting drug delivery compositions

Publications (1)

Publication Number	Publication Date
PL1740154T3 true PL1740154T3 (pl)	2009-11-30

Family

ID=34963134

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL05728268T PL1740154T3 (pl)	2004-03-12	2005-03-11	Kompozycje insuliny o ulepszonym wchłanianiu
PL10185350T PL2319500T3 (pl)	2004-03-12	2005-03-11	Szybko działające kompozycje do dostarczania leku

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL10185350T PL2319500T3 (pl)	2004-03-12	2005-03-11	Szybko działające kompozycje do dostarczania leku

Country Status (14)

Country	Link
US (2)	US7279457B2 (pl)
EP (3)	EP2106790B1 (pl)
JP (2)	JP5022213B2 (pl)
AT (1)	ATE433746T1 (pl)
AU (1)	AU2005222613B2 (pl)
CA (1)	CA2558835C (pl)
CY (1)	CY1109235T1 (pl)
DE (1)	DE602005014962D1 (pl)
DK (2)	DK1740154T3 (pl)
ES (3)	ES2398838T3 (pl)
PL (2)	PL1740154T3 (pl)
PT (2)	PT2319500E (pl)
SI (1)	SI1740154T1 (pl)
WO (1)	WO2005089722A1 (pl)

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2005
- 2005-03-11 PL PL05728268T patent/PL1740154T3/pl unknown
- 2005-03-11 PL PL10185350T patent/PL2319500T3/pl unknown
- 2005-03-11 ES ES10185350T patent/ES2398838T3/es not_active Expired - Lifetime
- 2005-03-11 US US11/077,604 patent/US7279457B2/en active Active
- 2005-03-11 PT PT101853505T patent/PT2319500E/pt unknown
- 2005-03-11 AT AT05728268T patent/ATE433746T1/de active
- 2005-03-11 ES ES05728268T patent/ES2328048T3/es not_active Expired - Lifetime
- 2005-03-11 ES ES09007867T patent/ES2398318T3/es not_active Expired - Lifetime
- 2005-03-11 AU AU2005222613A patent/AU2005222613B2/en not_active Ceased
- 2005-03-11 WO PCT/US2005/008187 patent/WO2005089722A1/en not_active Ceased
- 2005-03-11 SI SI200530737T patent/SI1740154T1/sl unknown
- 2005-03-11 DK DK05728268T patent/DK1740154T3/da active
- 2005-03-11 PT PT05728268T patent/PT1740154E/pt unknown
- 2005-03-11 EP EP09007867A patent/EP2106790B1/en not_active Revoked
- 2005-03-11 DE DE602005014962T patent/DE602005014962D1/de not_active Expired - Lifetime
- 2005-03-11 DK DK10185350.5T patent/DK2319500T3/da active
- 2005-03-11 EP EP10185350A patent/EP2319500B1/en not_active Revoked
- 2005-03-11 CA CA2558835A patent/CA2558835C/en not_active Expired - Lifetime
- 2005-03-11 EP EP05728268A patent/EP1740154B1/en not_active Expired - Lifetime
- 2005-03-11 JP JP2007503051A patent/JP5022213B2/ja not_active Expired - Lifetime
2007
- 2007-06-25 US US11/767,698 patent/US20070235365A1/en not_active Abandoned
2009
- 2009-07-20 CY CY20091100768T patent/CY1109235T1/el unknown
2012
- 2012-02-03 JP JP2012021473A patent/JP5272086B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US20070235365A1 (en)	2007-10-11
EP2319500A1 (en)	2011-05-11
DE602005014962D1 (de)	2009-07-30
EP2319500B1 (en)	2012-10-24
AU2005222613A1 (en)	2005-09-29
ES2398838T3 (es)	2013-03-22
DK1740154T3 (da)	2009-08-31
JP5272086B2 (ja)	2013-08-28
SI1740154T1 (sl)	2009-10-31
EP1740154B1 (en)	2009-06-17
CA2558835A1 (en)	2005-09-29
PT2319500E (pt)	2013-01-23
EP1740154A1 (en)	2007-01-10
JP2007528902A (ja)	2007-10-18
WO2005089722A1 (en)	2005-09-29
HK1099707A1 (en)	2007-08-24
DK2319500T3 (da)	2013-02-04
EP2106790B1 (en)	2012-10-24
HK1136215A1 (en)	2010-06-25
US7279457B2 (en)	2007-10-09
ATE433746T1 (de)	2009-07-15
PL2319500T3 (pl)	2013-05-31
JP2012087153A (ja)	2012-05-10
ES2328048T3 (es)	2009-11-06
ES2398318T3 (es)	2013-03-15
EP2106790A1 (en)	2009-10-07
PT1740154E (pt)	2009-09-11
CA2558835C (en)	2011-06-28
AU2005222613B2 (en)	2009-12-17
US20050214251A1 (en)	2005-09-29
JP5022213B2 (ja)	2012-09-12
CY1109235T1 (el)	2014-07-02

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