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PL1675956T3 - Minimalna sekwencja DNA działająca jako insulator chromatyny i jej zastosowanie do wyrażania białek - Google Patents

Minimalna sekwencja DNA działająca jako insulator chromatyny i jej zastosowanie do wyrażania białek

Info

Publication number
PL1675956T3
PL1675956T3 PL04791263T PL04791263T PL1675956T3 PL 1675956 T3 PL1675956 T3 PL 1675956T3 PL 04791263 T PL04791263 T PL 04791263T PL 04791263 T PL04791263 T PL 04791263T PL 1675956 T3 PL1675956 T3 PL 1675956T3
Authority
PL
Poland
Prior art keywords
dna sequence
protein expression
chromatin insulator
minimal dna
sequence acting
Prior art date
Application number
PL04791263T
Other languages
English (en)
Inventor
Philippe Chatellard
Markus Imhof
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of PL1675956T3 publication Critical patent/PL1675956T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL04791263T 2003-10-21 2004-10-20 Minimalna sekwencja DNA działająca jako insulator chromatyny i jej zastosowanie do wyrażania białek PL1675956T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03103890 2003-10-21
EP04791263A EP1675956B1 (en) 2003-10-21 2004-10-20 Minimal dna sequence acting as a chromatin insulator and its use in protein expression
PCT/EP2004/052591 WO2005040384A1 (en) 2003-10-21 2004-10-20 Minimal dna sequence acting as a chromatin insulator and its use in protein expression

Publications (1)

Publication Number Publication Date
PL1675956T3 true PL1675956T3 (pl) 2011-06-30

Family

ID=34486337

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04791263T PL1675956T3 (pl) 2003-10-21 2004-10-20 Minimalna sekwencja DNA działająca jako insulator chromatyny i jej zastosowanie do wyrażania białek

Country Status (17)

Country Link
US (1) US8133699B2 (pl)
EP (1) EP1675956B1 (pl)
JP (1) JP4745972B2 (pl)
AT (1) ATE484591T1 (pl)
AU (1) AU2004284243B2 (pl)
CA (1) CA2541523A1 (pl)
CY (1) CY1110868T1 (pl)
DE (1) DE602004029598D1 (pl)
DK (1) DK1675956T3 (pl)
ES (1) ES2354160T3 (pl)
HR (1) HRP20100560T1 (pl)
IL (1) IL175021A (pl)
NO (1) NO338767B1 (pl)
PL (1) PL1675956T3 (pl)
PT (1) PT1675956E (pl)
SI (1) SI1675956T1 (pl)
WO (1) WO2005040384A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE437233T1 (de) 2001-01-26 2009-08-15 Selexis Sa Matrix-anheftungsregionen und verfahren zu deren verwendung
BRPI0408246A (pt) 2003-03-11 2006-03-01 Applied Research Systems vetores de expressão que compreendem o promotor ie2 do mcmv
US20080076708A1 (en) * 2003-05-13 2008-03-27 Valter Altarocca Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
IN2014DN02484A (pl) 2003-10-24 2015-05-15 Selexis Sa
PT1689777E (pt) * 2003-11-05 2007-05-31 Ares Trading Sa Processo para a purificação da proteína de ligação a il-18
HRP20070474T3 (en) 2004-03-01 2007-11-30 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
EP1761552B1 (en) * 2004-06-29 2008-09-17 Ares Trading S.A. Process for the purification of il-18 binding protein
PL2267024T3 (pl) * 2005-06-03 2012-10-31 Ares Trading Sa Wytwarzanie rekombinowanego białka wiążącego IL-18
HRP20110948T1 (hr) 2005-06-10 2012-01-31 Ares Trading S.A. Postupak za pročišćavanje il-18 vezujućeg proteina
EP1760092A1 (en) * 2005-08-26 2007-03-07 Applied Research Systems ARS Holding N.V. System for screening cells for high expression of a protein of interest
FR2919616A1 (fr) * 2007-08-02 2009-02-06 Ecole Norm Superieure Lyon Polynucleotides insulateurs derives de l'element d4z4 et leurs utilisations en transgenese
WO2012139195A1 (en) 2011-04-13 2012-10-18 National Research Council Of Canada EXPRESSION SYSTEM WITH SAR ELEMENT FROM IFNα2
WO2013096056A1 (en) * 2011-12-21 2013-06-27 Danisco Us Inc. Improving fungal gene expression using insulator dna sequences
JP6297559B2 (ja) * 2012-07-31 2018-03-20 バジル・エム・ハンタッシュＢａｓｉｌ Ｍ． ＨＡＮＴＡＳＨ Ｈｌａｇ改変された細胞および方法
KR101591823B1 (ko) * 2013-12-27 2016-02-04 재단법인 목암생명공학연구소 증가된 유전자 발현능을 갖는 발현벡터
WO2017075395A1 (en) * 2015-10-28 2017-05-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Tumor-specific adenovirus vectors and therapeutic uses
MY189674A (en) 2015-10-28 2022-02-24 Sangamo Therapeutics Inc Liver-specific constructs, factor viii expression cassettes and methods of use thereof
DK3478830T3 (da) 2016-07-01 2024-05-21 Resolve Therapeutics Llc Optimerede binucleasefusioner og metoder
CN106754817B (zh) * 2016-11-03 2021-02-05 山西省生物研究院有限公司 一种重组自分泌运动因子的表达方法
JP7374091B2 (ja) 2017-08-22 2023-11-06 サナバイオ， エルエルシー 可溶性インターフェロン受容体およびその使用
BR112022010373A2 (pt) * 2019-11-29 2022-08-16 Paros Bio Inc Terapia genética para doenças neurodegenerativas

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6113898A (en) * 1995-06-07 2000-09-05 Idec Pharmaceuticals Corporation Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
US6432700B1 (en) * 1997-03-03 2002-08-13 Cell Genesys, Inc. Adenovirus vectors containing heterologous transcription regulatory elements and methods of using same
US6194152B1 (en) * 1997-08-20 2001-02-27 Dendreon Corporation Prostate tumor polynucleotide compositions and methods of detection thereof
WO2000023606A1 (en) * 1998-10-22 2000-04-27 Medical College Of Georgia Institute, Inc. Long terminal repeat, enhancer, and insulator sequences for use in recombinant vectors
JP2003504016A (ja) 1999-06-30 2003-02-04 アメリカ合衆国 遺伝子発現の制御のための特異的エンハンサー遮断活性を有する絶縁体としてのｄｎａ結合タンパク質および配列
BRPI0408246A (pt) 2003-03-11 2006-03-01 Applied Research Systems vetores de expressão que compreendem o promotor ie2 do mcmv
US20080076708A1 (en) 2003-05-13 2008-03-27 Valter Altarocca Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
PT1689777E (pt) 2003-11-05 2007-05-31 Ares Trading Sa Processo para a purificação da proteína de ligação a il-18
HRP20070474T3 (en) 2004-03-01 2007-11-30 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
EP1761552B1 (en) 2004-06-29 2008-09-17 Ares Trading S.A. Process for the purification of il-18 binding protein
PL2267024T3 (pl) 2005-06-03 2012-10-31 Ares Trading Sa Wytwarzanie rekombinowanego białka wiążącego IL-18
HRP20110948T1 (hr) 2005-06-10 2012-01-31 Ares Trading S.A. Postupak za pročišćavanje il-18 vezujućeg proteina

Also Published As

Publication number Publication date
CY1110868T1 (el) 2015-06-10
US20070134761A1 (en) 2007-06-14
WO2005040384A1 (en) 2005-05-06
JP2007508833A (ja) 2007-04-12
AU2004284243A1 (en) 2005-05-06
NO338767B1 (no) 2016-10-17
DK1675956T3 (da) 2010-11-22
IL175021A (en) 2011-07-31
DE602004029598D1 (de) 2010-11-25
ES2354160T3 (es) 2011-03-10
NO20062315L (no) 2006-07-18
JP4745972B2 (ja) 2011-08-10
SI1675956T1 (sl) 2010-12-31
HRP20100560T1 (hr) 2010-11-30
ATE484591T1 (de) 2010-10-15
US8133699B2 (en) 2012-03-13
EP1675956A1 (en) 2006-07-05
PT1675956E (pt) 2010-11-04
AU2004284243B2 (en) 2010-11-04
CA2541523A1 (en) 2005-05-06
IL175021A0 (en) 2006-08-20
EP1675956B1 (en) 2010-10-13

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