PL1663216T3 - Kompozycje o zmodyfikowanym uwalnianiu zawierające takrolimus - Google Patents

Kompozycje o zmodyfikowanym uwalnianiu zawierające takrolimus

Info

Publication number: PL1663216T3
Authority: PL; Poland
Prior art keywords: tacrolimus; modified release; release compositions; hydrophilic; dispersed
Prior art date: 2003-08-29

Application number

PL04762794T

Other languages

English (en)

Inventor

Per Holm

Tomas Norling

Original Assignee

Veloxis Pharmaceuticals As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-08-29

Filing date

2004-08-30

Publication date

2012-03-30

2004-08-30 Application filed by Veloxis Pharmaceuticals As filed Critical Veloxis Pharmaceuticals As

2012-03-30 Publication of PL1663216T3 publication Critical patent/PL1663216T3/pl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
- A—HUMAN NECESSITIES
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- A61K9/2009—Inorganic compounds
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Immunology (AREA)
Dispersion Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Transplantation (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

PL04762794T 2003-08-29 2004-08-30 Kompozycje o zmodyfikowanym uwalnianiu zawierające takrolimus PL1663216T3 (pl)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
DKPA200301232		2003-08-29
DKPA200301837		2003-12-11
US52979303P	2003-12-15	2003-12-15
DKPA200400079		2004-01-21
DKPA200400467		2004-03-23
DKPA200400463		2004-03-23
PCT/DK2004/000573 WO2005020993A1 (en)	2003-08-29	2004-08-30	Modified release compositions comprising tacrolimus
EP04762794A EP1663216B1 (en)	2003-08-29	2004-08-30	Modified release compositions comprising tacrolimus

Publications (1)

Publication Number	Publication Date
PL1663216T3 true PL1663216T3 (pl)	2012-03-30

Family

ID=34280179

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL04762794T PL1663216T3 (pl)	2003-08-29	2004-08-30	Kompozycje o zmodyfikowanym uwalnianiu zawierające takrolimus
PL04762795T PL1663217T3 (pl)	2003-08-29	2004-08-30	Stałe dyspersje zawierające takrolimus

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL04762795T PL1663217T3 (pl)	2003-08-29	2004-08-30	Stałe dyspersje zawierające takrolimus

Country Status (11)

Country	Link
US (15)	US7994214B2 (pl)
EP (2)	EP1663217B1 (pl)
JP (2)	JP4996249B2 (pl)
AT (1)	ATE473003T1 (pl)
AU (2)	AU2004267909B2 (pl)
BR (2)	BRPI0414000B8 (pl)
CA (2)	CA2537044C (pl)
DE (1)	DE602004028023D1 (pl)
NO (2)	NO334986B1 (pl)
PL (2)	PL1663216T3 (pl)
WO (2)	WO2005020994A1 (pl)

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- 2004-08-30 BR BRPI0414000A patent/BRPI0414000B8/pt active IP Right Grant
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- 2004-08-30 JP JP2006524226A patent/JP4996249B2/ja not_active Expired - Lifetime
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Publication number	Publication date
US20180214422A1 (en)	2018-08-02
AU2004267910A1 (en)	2005-03-10
US7994214B2 (en)	2011-08-09
US20140065225A1 (en)	2014-03-06
EP1663216A1 (en)	2006-06-07
US20140073665A1 (en)	2014-03-13
US20110251232A1 (en)	2011-10-13
US20180228779A1 (en)	2018-08-16
EP1663217A1 (en)	2006-06-07
US8623411B2 (en)	2014-01-07
US20160166551A1 (en)	2016-06-16
US8586084B2 (en)	2013-11-19
BRPI0413927A (pt)	2006-10-24
US8486993B2 (en)	2013-07-16
US20110263632A1 (en)	2011-10-27
EP1663217B1 (en)	2010-07-07
US8623410B2 (en)	2014-01-07
US20140066473A1 (en)	2014-03-06
US20110251231A1 (en)	2011-10-13
US20160243090A1 (en)	2016-08-25
BRPI0414000B1 (pt)	2019-11-05
DE602004028023D1 (de)	2010-08-19
AU2004267909B2 (en)	2008-12-18
JP4996249B2 (ja)	2012-08-08
US20110250277A1 (en)	2011-10-13
US20100008984A1 (en)	2010-01-14
US11129815B2 (en)	2021-09-28
BRPI0413927B1 (pt)	2019-11-12
US9757362B2 (en)	2017-09-12
US11077096B2 (en)	2021-08-03
WO2005020993A1 (en)	2005-03-10
JP2011251972A (ja)	2011-12-15
BRPI0414000B8 (pt)	2021-05-25
BRPI0414000A (pt)	2006-10-24
US20110256190A1 (en)	2011-10-20
US20200289478A1 (en)	2020-09-17
CA2537044A1 (en)	2005-03-10
NO334986B1 (no)	2014-08-18
JP2007504102A (ja)	2007-03-01
AU2004267910B2 (en)	2011-01-06
WO2005020994A1 (en)	2005-03-10
NO20061430L (no)	2006-05-29
PL1663217T3 (pl)	2010-12-31
NO337869B1 (no)	2016-07-04
US8617599B2 (en)	2013-12-31
NO20061429L (no)	2006-05-29
US8889186B2 (en)	2014-11-18
US8889185B2 (en)	2014-11-18
CA2537041A1 (en)	2005-03-10
BRPI0413927B8 (pt)	2021-05-25
CA2537041C (en)	2012-04-03
AU2004267909A1 (en)	2005-03-10
US20130189318A1 (en)	2013-07-25
US9161907B2 (en)	2015-10-20
ATE473003T1 (de)	2010-07-15
CA2537044C (en)	2012-04-17
EP1663216B1 (en)	2011-11-02
US10548880B2 (en)	2020-02-04
US9763920B2 (en)	2017-09-19
HK1096032A1 (en)	2007-05-25

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PL1663216T3 (pl)	2012-03-30	Kompozycje o zmodyfikowanym uwalnianiu zawierające takrolimus
SI1663216T1 (sl)	2012-03-30	Sestavek z modificiranim sproščanjem ki vsebuje takrolimus
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BRPI0509165A (pt)	2007-09-11	composições de liberação prolongada compreendendo torasemida e um polìmero formador de matriz