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PH12019500671B1 - Granular preparation - Google Patents

Granular preparation

Info

Publication number
PH12019500671B1
PH12019500671B1 PH1/2019/500671A PH12019500671A PH12019500671B1 PH 12019500671 B1 PH12019500671 B1 PH 12019500671B1 PH 12019500671 A PH12019500671 A PH 12019500671A PH 12019500671 B1 PH12019500671 B1 PH 12019500671B1
Authority
PH
Philippines
Prior art keywords
granular preparation
valine
leucine
present
isoleucine
Prior art date
Application number
PH1/2019/500671A
Other languages
English (en)
Other versions
PH12019500671A1 (en
Inventor
Jun Kosaka
Chisato Makino
Nobutaka Ninomiya
Yasushi Tanikawa
Original Assignee
Ea Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ea Pharma Co Ltd filed Critical Ea Pharma Co Ltd
Publication of PH12019500671A1 publication Critical patent/PH12019500671A1/en
Publication of PH12019500671B1 publication Critical patent/PH12019500671B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PH1/2019/500671A 2017-02-21 2018-02-20 Granular preparation PH12019500671B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017030368 2017-02-21
PCT/JP2018/005990 WO2018155435A1 (ja) 2017-02-21 2018-02-20 顆粒製剤

Publications (2)

Publication Number Publication Date
PH12019500671A1 PH12019500671A1 (en) 2019-07-24
PH12019500671B1 true PH12019500671B1 (en) 2024-02-02

Family

ID=63253165

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2019/500671A PH12019500671B1 (en) 2017-02-21 2018-02-20 Granular preparation

Country Status (6)

Country Link
JP (1) JP7080215B2 (ja)
KR (1) KR102555664B1 (ja)
CN (1) CN109789120A (ja)
PH (1) PH12019500671B1 (ja)
SG (1) SG10202109130WA (ja)
WO (1) WO2018155435A1 (ja)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836098T3 (de) * 1997-12-20 2014-04-30 Genencor International, Inc. In einem wirbelschichtbett hergestelltes matrixgranulat
EP1100466A1 (en) * 1998-07-31 2001-05-23 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition having improved taste
JP3211824B1 (ja) * 2000-10-26 2001-09-25 味の素株式会社 分岐鎖アミノ酸含有医薬用顆粒製剤とその製造方法
KR101168189B1 (ko) * 2003-10-29 2012-07-25 시오노기세이야쿠가부시키가이샤 불쾌미를 개선한 피복 제제의 제조 방법
TWI503128B (zh) * 2007-07-31 2015-10-11 Ajinomoto Kk A granule preparation containing an amino acid with excellent taste
AU2009224254A1 (en) * 2008-03-11 2009-09-17 Takeda Pharmaceutical Company Limited Orally-disintegrating solid preparation
JP5360368B2 (ja) 2008-09-05 2013-12-04 味の素株式会社 服用感が改善された経口用アミノ酸製剤
JP5515943B2 (ja) * 2009-10-02 2014-06-11 味の素株式会社 分岐鎖アミノ酸を含有する顆粒、およびその製造方法
JP2013014590A (ja) 2012-08-02 2013-01-24 Otsuka Pharmaceut Co Ltd 消化管及び腎臓の萎縮抑制剤

Also Published As

Publication number Publication date
WO2018155435A1 (ja) 2018-08-30
SG10202109130WA (en) 2021-09-29
CN109789120A (zh) 2019-05-21
KR102555664B1 (ko) 2023-07-18
PH12019500671A1 (en) 2019-07-24
JPWO2018155435A1 (ja) 2019-12-12
KR20190117469A (ko) 2019-10-16
JP7080215B2 (ja) 2022-06-03

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