PH12016501245A1 - Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamine - Google Patents
Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamineInfo
- Publication number
- PH12016501245A1 PH12016501245A1 PH12016501245A PH12016501245A PH12016501245A1 PH 12016501245 A1 PH12016501245 A1 PH 12016501245A1 PH 12016501245 A PH12016501245 A PH 12016501245A PH 12016501245 A PH12016501245 A PH 12016501245A PH 12016501245 A1 PH12016501245 A1 PH 12016501245A1
- Authority
- PH
- Philippines
- Prior art keywords
- phenylephrine
- antihistamine
- stable
- maleate salt
- pharmaceutical composition
- Prior art date
Links
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical group CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 title abstract 3
- 229960001802 phenylephrine Drugs 0.000 title abstract 3
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001387 anti-histamine Effects 0.000 title abstract 2
- 239000000739 antihistaminic agent Substances 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 title abstract 2
- 150000002688 maleic acid derivatives Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
An aqueous oral liquid composition containing phenylephrine and a maleate salt of antihistamine, wherein the composition is palatable and the phenylephrine chemically stable even when exposed to high temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PH12016501245A PH12016501245A1 (en) | 2014-03-12 | 2016-06-23 | Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamine |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/PH2014/000008 WO2015137829A1 (en) | 2014-03-12 | 2014-03-12 | Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamine |
| PH12016501245A PH12016501245A1 (en) | 2014-03-12 | 2016-06-23 | Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12016501245A1 true PH12016501245A1 (en) | 2016-08-15 |
Family
ID=54072145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12016501245A PH12016501245A1 (en) | 2014-03-12 | 2016-06-23 | Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamine |
Country Status (2)
| Country | Link |
|---|---|
| PH (1) | PH12016501245A1 (en) |
| WO (1) | WO2015137829A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210162051A1 (en) * | 2018-07-09 | 2021-06-03 | Olufoyekemi BADEJO | Aqueous-based compositions |
| CN112472677A (en) * | 2020-11-12 | 2021-03-12 | 澳美制药厂有限公司 | Renin-resistant preparation and preparation method thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5759579A (en) * | 1996-12-05 | 1998-06-02 | American Home Products Corporation | Pharmaceutical suspension systems |
| US8940796B2 (en) * | 2006-02-21 | 2015-01-27 | Wyeth Llc | Phenylephrine liquid formulations |
| US9005652B2 (en) * | 2006-07-25 | 2015-04-14 | Wyeth | Chewable tablet containing phenylephrine |
| US8323695B2 (en) * | 2007-08-13 | 2012-12-04 | Mcneil-Ppc, Inc. | Method for stabilizing phenylephrine |
| US20110237616A1 (en) * | 2008-12-19 | 2011-09-29 | Novartis Ag | Phehylephrine formulations with improveds stability |
-
2014
- 2014-03-12 WO PCT/PH2014/000008 patent/WO2015137829A1/en not_active Ceased
-
2016
- 2016-06-23 PH PH12016501245A patent/PH12016501245A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015137829A1 (en) | 2015-09-17 |
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