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PH12016500640A1 - Method of producing l-amino acids - Google Patents

Method of producing l-amino acids

Info

Publication number
PH12016500640A1
PH12016500640A1 PH12016500640A PH12016500640A PH12016500640A1 PH 12016500640 A1 PH12016500640 A1 PH 12016500640A1 PH 12016500640 A PH12016500640 A PH 12016500640A PH 12016500640 A PH12016500640 A PH 12016500640A PH 12016500640 A1 PH12016500640 A1 PH 12016500640A1
Authority
PH
Philippines
Prior art keywords
producing
amino acids
weakened
expression
gene
Prior art date
Application number
PH12016500640A
Other versions
PH12016500640B1 (en
Inventor
Moon Jun Ok
Lim Sang Jo
Kwon Do Hyun
Lee Kwang Ho
Bae Hyun Won
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/KR2014/009468 external-priority patent/WO2015053552A1/en
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of PH12016500640A1 publication Critical patent/PH12016500640A1/en
Publication of PH12016500640B1 publication Critical patent/PH12016500640B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/03—Amine-lyases (4.3.3)
    • C12Y403/03007—4-Hydroxy-tetrahydrodipicolinate synthase (4.3.3.7)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Provided is a method of producing l-amino acids by using a recombinant coryneform microorganism in which the expression of a target gene is weakened by using a gene transcription inhibition method.
PH12016500640A 2013-10-11 2016-04-07 Method of producing l-amino acids PH12016500640B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20130121090 2013-10-11
KR1020140091307A KR101518860B1 (en) 2013-10-11 2014-07-18 Method for producing L-amino acid
PCT/KR2014/009468 WO2015053552A1 (en) 2013-10-11 2014-10-08 Method of producing l-amino acids

Publications (2)

Publication Number Publication Date
PH12016500640A1 true PH12016500640A1 (en) 2016-05-30
PH12016500640B1 PH12016500640B1 (en) 2016-05-30

Family

ID=53035683

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12016500640A PH12016500640B1 (en) 2013-10-11 2016-04-07 Method of producing l-amino acids

Country Status (16)

Country Link
JP (3) JP6291042B2 (en)
KR (1) KR101518860B1 (en)
CN (1) CN104561163B (en)
AR (1) AR097977A1 (en)
AU (2) AU2014332732B2 (en)
BR (1) BR112016008029A2 (en)
CA (1) CA2925659C (en)
DK (1) DK2860256T3 (en)
ES (1) ES2626048T3 (en)
GE (1) GEP20196943B (en)
JO (1) JO3255B1 (en)
MY (1) MY172463A (en)
PH (1) PH12016500640B1 (en)
PL (1) PL2860256T3 (en)
RU (2) RU2614258C2 (en)
UA (1) UA117935C2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101518860B1 (en) * 2013-10-11 2015-05-12 씨제이제일제당 (주) Method for producing L-amino acid
CN105734004B (en) * 2016-03-02 2020-06-19 廊坊梅花生物技术开发有限公司 Recombinant strain and preparation method and application thereof
KR101925930B1 (en) * 2017-07-24 2019-02-26 씨제이제일제당 주식회사 Microorganisms producing L-lysine and process for producing L-lysine using the same
EP3763819B1 (en) 2018-03-09 2025-11-19 CJ Cheiljedang Corporation Novel promoter and l-amino acid production method using same
KR102221040B1 (en) * 2019-05-09 2021-03-03 씨제이제일제당 주식회사 Microorganism producing L-amino acid and method of producing Method of L-amino acid using thereof
KR102134418B1 (en) * 2019-06-17 2020-07-16 씨제이제일제당 주식회사 A microorganism producing L-tyrosine and a method for producing L-tyrosine using thereof
KR102207867B1 (en) * 2020-01-21 2021-01-26 씨제이제일제당 주식회사 Method for producing L-amino acids using microorganisms containing NADP dependent glyceraldehyde-3-phosphate dehydrogenase
KR102527895B1 (en) * 2021-01-11 2023-04-28 씨제이제일제당 (주) GlxR protein variant or threonine production method using the same
CN115678933A (en) * 2022-09-26 2023-02-03 廊坊梅花生物技术开发有限公司 Method for improving lysine fermentation conversion rate

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649379B1 (en) * 1987-06-12 2003-11-18 Massachusetts Institute Of Technology Method and deregulated enzyme for threonine production
JP3036912B2 (en) * 1991-09-02 2000-04-24 協和醗酵工業株式会社 Gene expression regulatory DNA
US5766925A (en) * 1994-03-04 1998-06-16 Ajinomoto Co., Inc. Method of producing L-lysine
KR100268324B1 (en) * 1995-06-07 2000-10-16 에가시라 구니오 Method of Making L-Lysine
ATE263246T1 (en) * 1999-02-20 2004-04-15 Degussa METHOD FOR THE FERMENTATIVE PRODUCTION OF L-AMINO ACIDS USING CORYNEFORMER BACTERIA
ATE417094T1 (en) * 1999-12-24 2008-12-15 Ajinomoto Kk METHOD FOR PRODUCING L-AMINO ACID
AU2002230431A1 (en) * 2000-11-15 2002-05-27 Archer-Daniels-Midland Company Corynebacterium glutamicum promoters
KR100397423B1 (en) * 2001-02-13 2003-09-13 씨제이 주식회사 Process for producing L-threonine
DE10224088A1 (en) * 2002-05-31 2003-12-11 Degussa Process for the production of L-amino acids using coryneform bacteria which contain an attenuated mez gene
JP2004261150A (en) * 2003-03-04 2004-09-24 Ajinomoto Co Inc Method for producing objective material
JP2005006564A (en) 2003-06-19 2005-01-13 Japan Tobacco Inc Nitrate ion-inducing promoter
JP2010226956A (en) * 2007-07-23 2010-10-14 Ajinomoto Co Inc Method for producing l-lysine
KR101335853B1 (en) 2011-12-01 2013-12-02 씨제이제일제당 (주) A microorganism having L-amino acids and riboflavin productivity and a method of producing L-amino acids and riboflavin using the same
KR101518860B1 (en) * 2013-10-11 2015-05-12 씨제이제일제당 (주) Method for producing L-amino acid

Also Published As

Publication number Publication date
JP2020078312A (en) 2020-05-28
RU2651461C2 (en) 2018-04-19
UA117935C2 (en) 2018-10-25
JP6291042B2 (en) 2018-03-14
MY172463A (en) 2019-11-26
CA2925659A1 (en) 2015-04-16
BR112016008029A2 (en) 2017-10-03
CN104561163B (en) 2018-11-06
DK2860256T3 (en) 2017-06-06
ES2626048T3 (en) 2017-07-21
CA2925659C (en) 2018-10-23
JO3255B1 (en) 2018-09-16
AU2017272295B2 (en) 2019-05-16
CN104561163A (en) 2015-04-29
AU2017272295A1 (en) 2018-01-04
JP2018113966A (en) 2018-07-26
JP2016532439A (en) 2016-10-20
KR20150042692A (en) 2015-04-21
AU2014332732B2 (en) 2017-12-07
RU2016110804A (en) 2016-07-27
RU2015151124A (en) 2016-06-27
RU2614258C2 (en) 2017-03-24
GEP20196943B (en) 2019-02-11
JP6824918B2 (en) 2021-02-03
KR101518860B1 (en) 2015-05-12
PL2860256T3 (en) 2017-08-31
AR097977A1 (en) 2016-04-20
PH12016500640B1 (en) 2016-05-30
AU2014332732A1 (en) 2016-04-21

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