PE27899A1 - Formulacion de particulas revestidas - Google Patents
Formulacion de particulas revestidasInfo
- Publication number
- PE27899A1 PE27899A1 PE1997000854A PE00085497A PE27899A1 PE 27899 A1 PE27899 A1 PE 27899A1 PE 1997000854 A PE1997000854 A PE 1997000854A PE 00085497 A PE00085497 A PE 00085497A PE 27899 A1 PE27899 A1 PE 27899A1
- Authority
- PE
- Peru
- Prior art keywords
- formulation
- preference
- methyl
- polymer
- wax
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000002245 particle Substances 0.000 title 1
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 abstract 2
- 229960005017 olanzapine Drugs 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- -1 4-METHYL-1-PIPERAZINYL Chemical class 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 235000013871 bee wax Nutrition 0.000 abstract 1
- 239000012166 beeswax Substances 0.000 abstract 1
- 229940092738 beeswax Drugs 0.000 abstract 1
- 239000004203 carnauba wax Substances 0.000 abstract 1
- 235000013869 carnauba wax Nutrition 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 230000002085 persistent effect Effects 0.000 abstract 1
- 239000005060 rubber Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000001993 wax Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2663396P | 1996-09-24 | 1996-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE27899A1 true PE27899A1 (es) | 1999-03-12 |
Family
ID=21832952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1997000854A PE27899A1 (es) | 1996-09-24 | 1997-09-23 | Formulacion de particulas revestidas |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20010020032A1 (fr) |
| EP (1) | EP0830858A1 (fr) |
| JP (1) | JP2001501207A (fr) |
| KR (1) | KR20000048540A (fr) |
| CN (1) | CN1230883A (fr) |
| AR (1) | AR009802A1 (fr) |
| AU (1) | AU719788B2 (fr) |
| BR (1) | BR9713215A (fr) |
| CA (1) | CA2266448A1 (fr) |
| CO (1) | CO4910139A1 (fr) |
| CZ (1) | CZ98899A3 (fr) |
| EA (1) | EA001610B1 (fr) |
| HU (1) | HUP9904065A3 (fr) |
| ID (1) | ID21762A (fr) |
| IL (1) | IL128845A0 (fr) |
| NO (1) | NO991405L (fr) |
| PE (1) | PE27899A1 (fr) |
| PL (1) | PL332503A1 (fr) |
| TR (1) | TR199900651T2 (fr) |
| WO (1) | WO1998013027A1 (fr) |
| ZA (1) | ZA978517B (fr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9922271D0 (en) * | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Formulation |
| TWI275394B (en) * | 2000-01-26 | 2007-03-11 | Asahi Chemical Corp | Mizoribin tablet improved with color tone change |
| US6740753B2 (en) | 2001-01-04 | 2004-05-25 | Geneva Pharmaceuticals, Inc. | Olanzapine crystal modification |
| DE10232113A1 (de) * | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
| SI21303A (sl) * | 2002-10-18 | 2004-04-30 | Krka, Tovarna Zdravil, D.D.,, Novo Mesto | Farmacevtska formulacija olanzapina |
| JP2006523613A (ja) | 2002-12-20 | 2006-10-19 | エスティ．ジェイムス アソシエイト エルエルシー／フェイバー リサーチ シリーズ | 徐放性医薬投与のための被覆粒子 |
| SI21402A (sl) | 2003-02-12 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Obloženi delci in farmacevtske oblike |
| JP4808612B2 (ja) * | 2003-04-25 | 2011-11-02 | 田辺三菱製薬株式会社 | アルキレンジオキシベンゼン誘導体を含む経口投与用組成物 |
| WO2005009407A2 (fr) * | 2003-07-29 | 2005-02-03 | Ranbaxy Laboratories Limited | Formulations pharmaceutiques d'olanzapine administrees par voie orale |
| DE112005000641T5 (de) * | 2004-09-06 | 2007-09-06 | Shasun Chemicals and Drugs Ltd., Chennai | Neues Verfahren zur Herstellung einer pharmazeutisch reinen polymorphen Form I von Olanzapin |
| CZ200563A3 (cs) * | 2005-02-02 | 2006-10-11 | Zentiva, A. S. | Lécivý prípravek obsahující jako úcinnou slozku olanzapin a zpusob jeho výroby |
| WO2007049304A2 (fr) * | 2005-10-27 | 2007-05-03 | Jubilant Organosys Limited | Formulation pharmaceutique enrobee, stable, d'olanzapine et son procede de preparation |
| ES2279715B1 (es) * | 2005-12-26 | 2008-06-01 | Laboratorios Lesvi, S.L. | Formulacion oral de olanzapina. |
| US20070293479A1 (en) * | 2006-05-18 | 2007-12-20 | Osinga Niels J | Olanzapine pharmaceutical composition |
| WO2008004033A1 (fr) * | 2006-07-05 | 2008-01-10 | Bilim Ilac Sanayii Ve Ticaret A.S. | Formulation stable d'olanzapine contenant des antioxidants |
| AR063043A1 (es) * | 2006-09-29 | 2008-12-23 | Synthon Bv | Composicion farmaceutica de olanzapina |
| WO2011137274A1 (fr) * | 2010-04-30 | 2011-11-03 | Bristol-Myers Squibb Company | Compositions pharmaceutiques comportant du n-(4-(2-amino-3- chloropyridin-4-yloxy)-3-fluorophényl)-4-éthoxy-1-(4-fluorophényl)-2-oxo-1,2-dihydropyridine-3-carboxamide |
| WO2012153347A2 (fr) | 2011-05-04 | 2012-11-15 | Zentiva K.S. | Composition pharmaceutique d'olanzapine de forme 1 à administration par voie orale |
| WO2014153541A1 (fr) | 2013-03-21 | 2014-09-25 | Eupraxia Pharmaceuticals USA LLC | Composition à libération prolongée injectable et son procédé d'utilisation pour traiter une inflammation dans des articulations et la douleur associée à celle-ci |
| RU2018119121A (ru) | 2015-10-27 | 2019-11-28 | Юпраксия Фармасьютикалз Инк. | Лекарственные формы местных анастетиков с замедленным высвобождением |
| CN107007559B (zh) * | 2017-04-21 | 2020-05-15 | 浙江京新药业股份有限公司 | 一种稳定的口服药物组合物及其制备方法 |
| CN118593482A (zh) | 2017-12-05 | 2024-09-06 | 赛诺维信制药公司 | 非外消旋混合物及其用途 |
| KR20200110317A (ko) | 2017-12-05 | 2020-09-23 | 선오비온 파마슈티컬스 인코포레이티드 | 결정형 및 이의 제조 방법 |
| AU2020286441A1 (en) | 2019-06-04 | 2022-01-06 | Sunovion Pharmaceuticals Inc. | Modified release formulations and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820522A (en) * | 1987-07-27 | 1989-04-11 | Mcneilab, Inc. | Oral sustained release acetaminophen formulation and process |
| US5605897A (en) * | 1991-04-23 | 1997-02-25 | Eli Lilly And Company | 2-methyl-thieno-benzodiazepine |
| ZA922776B (en) * | 1991-04-29 | 1993-10-15 | Lilly Co Eli | Pharmaceutical compounds |
| JPH05194225A (ja) * | 1991-11-07 | 1993-08-03 | Yoshitomi Pharmaceut Ind Ltd | 安定化された抗潰瘍剤含有製剤 |
| ES2153373T3 (es) * | 1992-05-29 | 2001-03-01 | Lilly Co Eli | Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central. |
| SE9302395D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | New pharmaceutical formulation |
| US5637584A (en) * | 1995-03-24 | 1997-06-10 | Eli Lilly And Company | Solvate of olanzapine |
| CR5278A (es) * | 1995-03-24 | 1996-07-04 | Lilly Co Eli | Formulacion oral de 2-metil-tieno-benzodiacepina |
| EP0733368A1 (fr) * | 1995-03-24 | 1996-09-25 | Eli Lilly And Company | Formulations d'olanzapine granulaires |
-
1997
- 1997-09-18 TR TR1999/00651T patent/TR199900651T2/xx unknown
- 1997-09-18 CZ CZ99988A patent/CZ98899A3/cs unknown
- 1997-09-18 CN CN97198099A patent/CN1230883A/zh active Pending
- 1997-09-18 HU HU9904065A patent/HUP9904065A3/hu unknown
- 1997-09-18 CA CA002266448A patent/CA2266448A1/fr not_active Abandoned
- 1997-09-18 WO PCT/US1997/016547 patent/WO1998013027A1/fr not_active Ceased
- 1997-09-18 PL PL97332503A patent/PL332503A1/xx unknown
- 1997-09-18 AU AU44230/97A patent/AU719788B2/en not_active Ceased
- 1997-09-18 ID IDW990060A patent/ID21762A/id unknown
- 1997-09-18 KR KR1019990702455A patent/KR20000048540A/ko not_active Withdrawn
- 1997-09-18 BR BR9713215-2A patent/BR9713215A/pt not_active IP Right Cessation
- 1997-09-18 EA EA199900331A patent/EA001610B1/ru not_active IP Right Cessation
- 1997-09-18 IL IL12884597A patent/IL128845A0/xx unknown
- 1997-09-18 JP JP10515724A patent/JP2001501207A/ja not_active Ceased
- 1997-09-22 CO CO97055063A patent/CO4910139A1/es unknown
- 1997-09-22 EP EP97307380A patent/EP0830858A1/fr not_active Withdrawn
- 1997-09-22 ZA ZA978517A patent/ZA978517B/xx unknown
- 1997-09-23 PE PE1997000854A patent/PE27899A1/es not_active Application Discontinuation
- 1997-09-23 AR ARP970104363A patent/AR009802A1/es unknown
- 1997-09-23 US US08/935,882 patent/US20010020032A1/en not_active Abandoned
-
1999
- 1999-03-23 NO NO991405A patent/NO991405L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000048540A (ko) | 2000-07-25 |
| EA001610B1 (ru) | 2001-06-25 |
| JP2001501207A (ja) | 2001-01-30 |
| ZA978517B (en) | 1999-03-23 |
| PL332503A1 (en) | 1999-09-13 |
| CZ98899A3 (cs) | 1999-12-15 |
| HUP9904065A2 (hu) | 2000-04-28 |
| AR009802A1 (es) | 2000-05-03 |
| IL128845A0 (en) | 2000-01-31 |
| CA2266448A1 (fr) | 1998-04-02 |
| CN1230883A (zh) | 1999-10-06 |
| AU4423097A (en) | 1998-04-17 |
| HUP9904065A3 (en) | 2001-10-29 |
| ID21762A (id) | 1999-07-22 |
| BR9713215A (pt) | 2000-04-04 |
| EP0830858A1 (fr) | 1998-03-25 |
| TR199900651T2 (xx) | 1999-07-21 |
| EA199900331A1 (ru) | 2000-04-24 |
| AU719788B2 (en) | 2000-05-18 |
| NO991405D0 (no) | 1999-03-23 |
| NO991405L (no) | 1999-03-23 |
| CO4910139A1 (es) | 2000-04-24 |
| WO1998013027A1 (fr) | 1998-04-02 |
| US20010020032A1 (en) | 2001-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |