PE20212372A1 - Composiciones de acidos grasos poliinsaturados enriquecidos con dha - Google Patents
Composiciones de acidos grasos poliinsaturados enriquecidos con dhaInfo
- Publication number
- PE20212372A1 PE20212372A1 PE2021001814A PE2021001814A PE20212372A1 PE 20212372 A1 PE20212372 A1 PE 20212372A1 PE 2021001814 A PE2021001814 A PE 2021001814A PE 2021001814 A PE2021001814 A PE 2021001814A PE 20212372 A1 PE20212372 A1 PE 20212372A1
- Authority
- PE
- Peru
- Prior art keywords
- fatty acid
- amount
- composition
- polyunsaturated fatty
- weight
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title abstract 5
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 abstract 7
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 7
- 229930195729 fatty acid Natural products 0.000 abstract 7
- 239000000194 fatty acid Substances 0.000 abstract 7
- 235000020669 docosahexaenoic acid Nutrition 0.000 abstract 4
- 150000004665 fatty acids Chemical class 0.000 abstract 4
- 229940090949 docosahexaenoic acid Drugs 0.000 abstract 3
- -1 fatty acid salt Chemical class 0.000 abstract 3
- 150000002632 lipids Chemical class 0.000 abstract 3
- 235000013311 vegetables Nutrition 0.000 abstract 2
- 238000004821 distillation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/12—Refining fats or fatty oils by distillation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
- C11C3/02—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with glycerol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/02—Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
- C11C1/002—Sources of fatty acids, e.g. natural glycerides, characterised by the nature, the quantities or the distribution of said acids
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
- C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
- C11C1/04—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis
- C11C1/045—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis using enzymes or microorganisms, living or dead
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
- C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
- C11C1/04—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis
- C11C1/06—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis using solid catalysts
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
- C11C1/08—Refining
- C11C1/10—Refining by distillation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/18—Lipids
- A23V2250/186—Fatty acids
- A23V2250/1868—Docosahexaenoic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Fats And Perfumes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Edible Oils And Fats (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Referida a una composicion lipidica de base vegetal que comprende: (i) acido docosahexaenoico en una cantidad de 50 % a 85 % en peso del contenido total de acidos grasos de la composicion; (ii) un segundo acido graso poliinsaturado en una cantidad de 10 % a 90 % en peso del acido docosahexaenoico; y (iii) un tercer acido graso poliinsaturado en una cantidad de 10 % a 70 % en peso del segundo acido graso poliinsaturado; en donde la cantidad total de todos los otros acidos grasos en la composicion es de hasta 20 % en peso del contenido total de acidos grasos de la composicion, y en donde cada uno del acido docosahexaenoico, y el segundo y el tercer acido graso poliinsaturado se proporciona independientemente en la forma de un acido graso, una sal de acido graso, un ester de acido graso o una sal de un ester de acido graso; en donde la cantidad de EPA en la composicion es menor de 10 % en peso de la cantidad de DHA; en donde la composicion lipidica se obtiene mediante un proceso que comprende la transesterificacion y la destilacion de un lipido de base vegetal.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18179080.9A EP3586643A1 (en) | 2018-06-21 | 2018-06-21 | Dha enriched polyunsaturated fatty acid compositions |
| PCT/EP2018/086382 WO2019242875A1 (en) | 2018-06-21 | 2018-12-20 | Dha enriched polyunsaturated fatty acid compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20212372A1 true PE20212372A1 (es) | 2021-12-22 |
Family
ID=62841828
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2021001814A PE20212372A1 (es) | 2018-06-21 | 2018-12-20 | Composiciones de acidos grasos poliinsaturados enriquecidos con dha |
| PE2020002102A PE20211482A1 (es) | 2018-06-21 | 2018-12-20 | Composiciones de acidos grasos poliinsaturados enriquecidos con dha |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2020002102A PE20211482A1 (es) | 2018-06-21 | 2018-12-20 | Composiciones de acidos grasos poliinsaturados enriquecidos con dha |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20210254110A1 (es) |
| EP (2) | EP3586643A1 (es) |
| JP (2) | JP7602377B2 (es) |
| KR (1) | KR20210038882A (es) |
| CN (1) | CN112752511A (es) |
| AR (1) | AR113710A1 (es) |
| AU (1) | AU2018428608B2 (es) |
| CA (1) | CA3104224A1 (es) |
| CL (1) | CL2020003281A1 (es) |
| CO (1) | CO2021000430A2 (es) |
| ES (1) | ES3037967T3 (es) |
| MX (1) | MX2020013990A (es) |
| PE (2) | PE20212372A1 (es) |
| PL (1) | PL3809860T3 (es) |
| TW (1) | TWI706727B (es) |
| WO (1) | WO2019242875A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3586642A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Ala enriched polyunsaturated fatty acid compositions |
| EP3586640A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1205043B (it) | 1987-05-28 | 1989-03-10 | Innova Di Ridolfi Flora & C S | Procedimento per l'estrazione di esteri di acidi grassi poliinsaturi da olii di pesce e composizioni farmaceutiche e dietetiche contenenti detti esteri |
| US20040209953A1 (en) | 2002-12-06 | 2004-10-21 | Wai Lee Theresa Siu-Ling | Glyceride compositions and methods of making and using same |
| JP3884465B2 (ja) | 2003-07-09 | 2007-02-21 | 株式会社J−オイルミルズ | 長鎖高度不飽和脂肪酸を含む抗酸化油脂組成物 |
| JP2010516230A (ja) * | 2007-01-03 | 2010-05-20 | モンサント テクノロジー エルエルシー | ステアリドン酸を取り込む食物組成物 |
| AU2008269989B2 (en) * | 2007-06-29 | 2014-02-27 | Dsm Ip Assets B.V. | Production and purification of esters of polyunsaturated fatty acids |
| KR101650680B1 (ko) * | 2007-08-31 | 2016-08-23 | 디에스엠 아이피 어셋츠 비.브이. | 다중불포화된 지방산 함유 고체 지방 조성물 및 그의 용도 및 생산 |
| JP2014510166A (ja) | 2011-02-11 | 2014-04-24 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 短行程蒸留を使用する微生物源からのトリグリセリド油の精製 |
| WO2013033618A1 (en) * | 2011-09-02 | 2013-03-07 | Arctic Nutrition As | Lipid compositions with high dha content |
| HUE033766T2 (en) | 2012-06-15 | 2018-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| CN110876413A (zh) | 2012-09-11 | 2020-03-13 | 美国陶氏益农公司 | 与dha共混的ω-9芸苔油 |
| MX372724B (es) | 2012-12-24 | 2020-06-19 | Qualitas Health Inc | Formulaciones de acido eicosapentaenoico (epa). |
| EA037817B1 (ru) * | 2013-12-18 | 2021-05-25 | Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн | Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты |
| CA2953008C (en) | 2014-06-27 | 2024-03-19 | Nuseed Pty Ltd | Lipid comprising docosapentaenoic acid |
| AU2016262315B2 (en) | 2015-05-13 | 2020-09-03 | Epax Norway As | Very long chain polyunsaturated fatty acids from natural oils |
| IL296501B2 (en) | 2016-06-16 | 2025-07-01 | Nuseed Nutritional Australia Pty Ltd | Canola NS–B50027–4 |
| KR102420456B1 (ko) | 2016-06-16 | 2022-07-14 | 누시드 뉴트리셔널 오스트레일리아 피티와이 엘티디. | 근친교배 형질전환 카놀라 계통 ns-b50027-4 및 이의 종자 |
-
2018
- 2018-06-21 EP EP18179080.9A patent/EP3586643A1/en not_active Withdrawn
- 2018-12-20 US US17/253,944 patent/US20210254110A1/en active Pending
- 2018-12-20 WO PCT/EP2018/086382 patent/WO2019242875A1/en not_active Ceased
- 2018-12-20 CN CN201880094810.4A patent/CN112752511A/zh active Pending
- 2018-12-20 CA CA3104224A patent/CA3104224A1/en active Pending
- 2018-12-20 ES ES18829388T patent/ES3037967T3/es active Active
- 2018-12-20 PE PE2021001814A patent/PE20212372A1/es unknown
- 2018-12-20 AU AU2018428608A patent/AU2018428608B2/en active Active
- 2018-12-20 EP EP18829388.0A patent/EP3809860B1/en active Active
- 2018-12-20 MX MX2020013990A patent/MX2020013990A/es unknown
- 2018-12-20 PL PL18829388.0T patent/PL3809860T3/pl unknown
- 2018-12-20 JP JP2020571371A patent/JP7602377B2/ja active Active
- 2018-12-20 KR KR1020217002093A patent/KR20210038882A/ko active Pending
- 2018-12-20 PE PE2020002102A patent/PE20211482A1/es unknown
- 2018-12-21 AR ARP180103840A patent/AR113710A1/es active IP Right Grant
- 2018-12-21 TW TW107146461A patent/TWI706727B/zh active
-
2020
- 2020-12-17 CL CL2020003281A patent/CL2020003281A1/es unknown
-
2021
- 2021-01-18 CO CONC2021/0000430A patent/CO2021000430A2/es unknown
-
2024
- 2024-08-27 JP JP2024145880A patent/JP2024156003A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3809860A1 (en) | 2021-04-28 |
| MX2020013990A (es) | 2021-05-27 |
| WO2019242875A1 (en) | 2019-12-26 |
| JP7602377B2 (ja) | 2024-12-18 |
| TW202000044A (zh) | 2020-01-01 |
| AU2018428608B2 (en) | 2025-02-27 |
| KR20210038882A (ko) | 2021-04-08 |
| PL3809860T3 (pl) | 2025-12-08 |
| EP3809860B1 (en) | 2025-06-18 |
| ES3037967T3 (en) | 2025-10-08 |
| CO2021000430A2 (es) | 2021-04-30 |
| BR112020026074A8 (pt) | 2023-02-28 |
| PE20211482A1 (es) | 2021-08-05 |
| CN112752511A (zh) | 2021-05-04 |
| JP2024156003A (ja) | 2024-10-31 |
| EP3586643A1 (en) | 2020-01-01 |
| EP3809860C0 (en) | 2025-06-18 |
| BR112020026074A2 (pt) | 2021-03-23 |
| CL2020003281A1 (es) | 2021-07-09 |
| CA3104224A1 (en) | 2019-12-26 |
| US20210254110A1 (en) | 2021-08-19 |
| TWI706727B (zh) | 2020-10-11 |
| AR113710A1 (es) | 2020-06-03 |
| JP2021527434A (ja) | 2021-10-14 |
| AU2018428608A1 (en) | 2021-02-11 |
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