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Priority claimed from EP16177896.4Aexternal-prioritypatent/EP3266458A1/en
Priority claimed from BR102016015716-1Aexternal-prioritypatent/BR102016015716A2/en
Application filed by Fagron B VfiledCriticalFagron B V
Publication of PE20180458A1publicationCriticalpatent/PE20180458A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Medicinal Preparation
(AREA)
Abstract
Se refiere a una composicion farmaceutica que comprende una prostaglandina vasoactiva tal como alprostadil, entre otros y un vehiculo farmaceuticamente aceptable que comprende: a) lecitina; b) palmitato de isopropilo y c) urea, donde dicho vehiculo comprende miristato de isopropilo o un poloxamero, preferiblemente un poloxamero 407 y se formula como una crema con una viscosidad a 25°C de entre 25.000 a 200.000 mPa. Tambien se refiere a un metodo de preparacion, un aplicador y un kit. Dicha composicion es util en el tratamiento de la disfuncion erectil masculinaIt refers to a pharmaceutical composition comprising a vasoactive prostaglandin such as alprostadil, among others, and a pharmaceutically acceptable carrier comprising: a) lecithin; b) isopropyl palmitate and c) urea, wherein said carrier comprises isopropyl myristate or a poloxamer, preferably a poloxamer 407 and is formulated as a cream with a viscosity at 25 ° C of between 25,000 to 200,000 mPa. It also refers to a method of preparation, an applicator and a kit. This composition is useful in the treatment of male erectile dysfunction
PE2016001554A2016-07-052016-08-31
METHOD AND COMPOSITION AND KIT TO TREAT ERECTILE DYSFUNCTION
PE20180458A1
(en)
"Substituted spirocycle derived compounds, atx inhibitors; pharmaceutical composition comprising them; and its use in the treatment of cancer, inflammations, neuropathic pain, fibrotic diseases, thrombosis, among others ”. pct