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PE20171112A1 - Nuevos compuestos hidrosolubles derivados del bencimidazol, utiles para el tratamiento de la fasciolosis - Google Patents

Nuevos compuestos hidrosolubles derivados del bencimidazol, utiles para el tratamiento de la fasciolosis

Info

Publication number
PE20171112A1
PE20171112A1 PE2017000898A PE2017000898A PE20171112A1 PE 20171112 A1 PE20171112 A1 PE 20171112A1 PE 2017000898 A PE2017000898 A PE 2017000898A PE 2017000898 A PE2017000898 A PE 2017000898A PE 20171112 A1 PE20171112 A1 PE 20171112A1
Authority
PE
Peru
Prior art keywords
benzimidazole
fasciolosis
useful
treatment
soluble compounds
Prior art date
Application number
PE2017000898A
Other languages
English (en)
Inventor
Bocanegra Rafael Castillo
Ramos Miguel Angel Flores
Campos Maria Alicia Hernandez
Velarde Osvaldo Froylan Ibarra
Montenegro Remedios Yolanda Vera
Original Assignee
Univ Mexico Nacional Autonoma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56074744&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20171112(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Mexico Nacional Autonoma filed Critical Univ Mexico Nacional Autonoma
Publication of PE20171112A1 publication Critical patent/PE20171112A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • C07F9/65068—Five-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se refiere a compuestos hidrosolubles derivados del bencimidazol representados por la formula general I, donde: Y1 e Y2 son O o S y por lo menos uno de Y1 e Y2 es O; cada uno o ambos R1 y R2 son H o cation; R3 es un alquilo de 1 a 4 C; R4 y R5 son halogeno o un alcoxido -OR6; R6 es arilo de 6 a 10 atomos de carbono unidos en la posicion 5- o 6- del nucleo de bencimidazol. Tambien se refiere a una composicion farmaceutica. Dichos compuestos son utiles en el tratamiento de fasciolosis
PE2017000898A 2014-11-26 2015-11-25 Nuevos compuestos hidrosolubles derivados del bencimidazol, utiles para el tratamiento de la fasciolosis PE20171112A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2014014417A MX365051B (es) 2014-11-26 2014-11-26 Nuevos compuestos hidrosolubles derivados del bencimidazol, utiles para el tratamiento de la fasciolosis.

Publications (1)

Publication Number Publication Date
PE20171112A1 true PE20171112A1 (es) 2017-08-07

Family

ID=56074744

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2017000898A PE20171112A1 (es) 2014-11-26 2015-11-25 Nuevos compuestos hidrosolubles derivados del bencimidazol, utiles para el tratamiento de la fasciolosis

Country Status (7)

Country Link
US (1) US10239842B2 (es)
BR (1) BR112017010938B1 (es)
CL (1) CL2017001320A1 (es)
CO (1) CO2017005118A2 (es)
MX (1) MX365051B (es)
PE (1) PE20171112A1 (es)
WO (1) WO2016085319A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108003188A (zh) * 2017-12-25 2018-05-08 长春吉大天元化学技术股份有限公司 一种烷基磷酸酯类化合物的新型纯化方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
ATE467637T1 (de) 2005-07-28 2010-05-15 Intervet Int Bv Neue benzimidazol(thio)carbamate mit antiparasitischer wirkung und ihre synthese

Also Published As

Publication number Publication date
CO2017005118A2 (es) 2017-09-20
MX2014014417A (es) 2016-05-26
US10239842B2 (en) 2019-03-26
US20170327470A1 (en) 2017-11-16
BR112017010938A2 (pt) 2018-07-03
CL2017001320A1 (es) 2017-12-29
MX365051B (es) 2019-05-09
WO2016085319A1 (es) 2016-06-02
BR112017010938B1 (pt) 2022-08-16

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