PE20160239A1 - SYNERGISTIC COMBINATION OF PARACETAMOL / CELECOXIB FOR THE TREATMENT OF INFLAMMATORY PAIN - Google Patents
SYNERGISTIC COMBINATION OF PARACETAMOL / CELECOXIB FOR THE TREATMENT OF INFLAMMATORY PAINInfo
- Publication number
- PE20160239A1 PE20160239A1 PE2016000043A PE2016000043A PE20160239A1 PE 20160239 A1 PE20160239 A1 PE 20160239A1 PE 2016000043 A PE2016000043 A PE 2016000043A PE 2016000043 A PE2016000043 A PE 2016000043A PE 20160239 A1 PE20160239 A1 PE 20160239A1
- Authority
- PE
- Peru
- Prior art keywords
- paracetamol
- celecoxib
- inflammatory pain
- treatment
- synergistic combination
- Prior art date
Links
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title abstract 3
- 206010065390 Inflammatory pain Diseases 0.000 title abstract 3
- RZEKVGVHFLEQIL-UHFFFAOYSA-N celecoxib Chemical compound C1=CC(C)=CC=C1C1=CC(C(F)(F)F)=NN1C1=CC=C(S(N)(=O)=O)C=C1 RZEKVGVHFLEQIL-UHFFFAOYSA-N 0.000 title abstract 3
- 229960000590 celecoxib Drugs 0.000 title abstract 3
- 229960005489 paracetamol Drugs 0.000 title abstract 3
- 239000011885 synergistic combination Substances 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se refiere a una combinacion de paracetamol y celecoxib que en cantidades especificas generan una potenciacion analgesica contra el dolor de tipo inflamatorio. Especificamente, la invencion se refiere a una combinacion sinergistica de entre 375 a 500 mg de paracetamol y de entre 50 a 75 mg de celecoxib util para el tratamiento de dolor inflamatorio en animales y seres humanos, asi como el uso de dichos principios activos en las cantidades indicadas en la preparacion de combinaciones farmaceuticas sinergistas.It refers to a combination of paracetamol and celecoxib that in specific amounts generate an analgesic potentiation against inflammatory pain. Specifically, the invention relates to a synergistic combination of between 375 to 500 mg of paracetamol and between 50 to 75 mg of celecoxib useful for the treatment of inflammatory pain in animals and humans, as well as the use of said active principles in the amounts indicated in the preparation of synergistic pharmaceutical combinations.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2013/055710 WO2015004505A1 (en) | 2013-07-11 | 2013-07-11 | Synergistic combination of paracetamol/celecoxib for the treatment of inflammatory pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20160239A1 true PE20160239A1 (en) | 2016-05-13 |
Family
ID=52279400
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2016000043A PE20160239A1 (en) | 2013-07-11 | 2014-07-11 | SYNERGISTIC COMBINATION OF PARACETAMOL / CELECOXIB FOR THE TREATMENT OF INFLAMMATORY PAIN |
| PE2016002763A PE20170305A1 (en) | 2013-07-11 | 2014-07-11 | SYNERGISTIC COMBINATION OF PARACETAMOL / CELECOXIB FOR THE TREATMENT OF INFLAMMATORY PAIN |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2016002763A PE20170305A1 (en) | 2013-07-11 | 2014-07-11 | SYNERGISTIC COMBINATION OF PARACETAMOL / CELECOXIB FOR THE TREATMENT OF INFLAMMATORY PAIN |
Country Status (8)
| Country | Link |
|---|---|
| CL (1) | CL2015003211A1 (en) |
| CR (1) | CR20160021A (en) |
| CU (1) | CU24440B1 (en) |
| DO (1) | DOP2016000008A (en) |
| EC (1) | ECSP16005679A (en) |
| MX (1) | MX366118B (en) |
| PE (2) | PE20160239A1 (en) |
| WO (2) | WO2015004505A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11147780B2 (en) * | 2020-02-24 | 2021-10-19 | Algia Pharma, Llc | Multidrug pain management package |
| PE20251234A1 (en) * | 2023-10-05 | 2025-04-29 | Laboratorios Silanes S A De C V | CELECOXIB-ACETAMINOPHEN COMBINATION WITH ENHANCED STABILITY AND PROCEDURE FOR ITS PREPARATION |
| PE20251233A1 (en) | 2023-10-05 | 2025-04-29 | Laboratorios Silanes S A De C V | MULTIACTIVE TABLET FOR THE TREATMENT AND CONTROL OF SEVERE CHRONIC PAIN AND PREPARATION METHOD |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE524186T1 (en) * | 2002-02-19 | 2011-09-15 | Adcock Ingram Ltd | PHARMACEUTICAL COMBINATIONS CONSISTING OF MELOXICAM, TRAMADOL AND PARACETAMOL |
| GB0423103D0 (en) * | 2004-10-19 | 2004-11-17 | Boots Healthcare Int Ltd | Therapeutic agents |
-
2013
- 2013-07-11 WO PCT/IB2013/055710 patent/WO2015004505A1/en not_active Ceased
-
2014
- 2014-07-11 PE PE2016000043A patent/PE20160239A1/en not_active Application Discontinuation
- 2014-07-11 PE PE2016002763A patent/PE20170305A1/en unknown
- 2014-07-11 WO PCT/IB2014/063019 patent/WO2015004634A2/en not_active Ceased
- 2014-07-11 MX MX2015013911A patent/MX366118B/en active IP Right Grant
- 2014-07-11 CU CU2016000002A patent/CU24440B1/en unknown
-
2015
- 2015-10-30 CL CL2015003211A patent/CL2015003211A1/en unknown
-
2016
- 2016-01-11 CR CR20160021A patent/CR20160021A/en unknown
- 2016-01-11 DO DO2016000008A patent/DOP2016000008A/en unknown
- 2016-02-11 EC ECIEPI20165679A patent/ECSP16005679A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CU20160002A7 (en) | 2016-06-29 |
| MX2015013911A (en) | 2015-12-08 |
| CL2015003211A1 (en) | 2016-04-29 |
| CU24440B1 (en) | 2019-09-04 |
| WO2015004634A2 (en) | 2015-01-15 |
| ECSP16005679A (en) | 2017-08-31 |
| PE20170305A1 (en) | 2017-04-21 |
| WO2015004634A3 (en) | 2015-04-09 |
| MX366118B (en) | 2019-06-27 |
| DOP2016000008A (en) | 2016-03-15 |
| CR20160021A (en) | 2016-04-08 |
| WO2015004505A1 (en) | 2015-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |