PE20160052A1 - Composicion farmaceutica de clorhidrato de s-cetamina - Google Patents
Composicion farmaceutica de clorhidrato de s-cetaminaInfo
- Publication number
- PE20160052A1 PE20160052A1 PE2015001997A PE2015001997A PE20160052A1 PE 20160052 A1 PE20160052 A1 PE 20160052A1 PE 2015001997 A PE2015001997 A PE 2015001997A PE 2015001997 A PE2015001997 A PE 2015001997A PE 20160052 A1 PE20160052 A1 PE 20160052A1
- Authority
- PE
- Peru
- Prior art keywords
- hydrochloride
- cetamine
- pharmaceutical composition
- formulation
- depression
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- YQEZLKZALYSWHR-ZDUSSCGKSA-N (S)-ketamine Chemical compound C=1C=CC=C(Cl)C=1[C@@]1(NC)CCCCC1=O YQEZLKZALYSWHR-ZDUSSCGKSA-N 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000013011 aqueous formulation Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229960004184 ketamine hydrochloride Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La invencion esta dirigida a una formulacion acuosa de clorhidrato de S-cetamina, preferentemente para la administracion nasal, en donde la formulacion no contiene un conservante antimicrobiano, ademas es util en el tratamiento de la depresion
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361791505P | 2013-03-15 | 2013-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20160052A1 true PE20160052A1 (es) | 2016-01-28 |
Family
ID=50549465
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2019002294A PE20191796A1 (es) | 2013-03-15 | 2014-03-14 | Composicion farmaceutica de clorhidrato de s-ketamina |
| PE2015001997A PE20160052A1 (es) | 2013-03-15 | 2014-03-14 | Composicion farmaceutica de clorhidrato de s-cetamina |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2019002294A PE20191796A1 (es) | 2013-03-15 | 2014-03-14 | Composicion farmaceutica de clorhidrato de s-ketamina |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20140275277A1 (es) |
| EP (3) | EP3498268A1 (es) |
| KR (3) | KR20230156807A (es) |
| CN (3) | CN116251084A (es) |
| AU (6) | AU2014228324B2 (es) |
| CL (1) | CL2015002733A1 (es) |
| CR (1) | CR20150480A (es) |
| CY (1) | CY1121928T1 (es) |
| DK (1) | DK2968221T3 (es) |
| ES (1) | ES2745024T3 (es) |
| HR (1) | HRP20191477T1 (es) |
| HU (1) | HUE045982T2 (es) |
| LT (1) | LT2968221T (es) |
| ME (1) | ME03465B (es) |
| MX (2) | MX373678B (es) |
| MY (2) | MY203693A (es) |
| NZ (1) | NZ712270A (es) |
| PE (2) | PE20191796A1 (es) |
| PH (2) | PH12021552333A1 (es) |
| PL (1) | PL2968221T3 (es) |
| PT (1) | PT2968221T (es) |
| RS (1) | RS59130B1 (es) |
| SG (3) | SG10201912735TA (es) |
| SI (1) | SI2968221T1 (es) |
| SM (1) | SMT201900472T1 (es) |
| WO (1) | WO2014143646A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3043785T3 (da) | 2013-09-13 | 2021-11-15 | Univ Chiba Nat Univ Corp | Anvendelse af r-ketamin og salt deraf som lægemidler |
| EP3094312B1 (en) * | 2014-01-14 | 2019-03-13 | Children's Hospital Medical Center | Compositions comprising ketamine for treating an autism spectrum disorder |
| US9844551B2 (en) | 2015-01-14 | 2017-12-19 | Children's Hospital Medical Center | Compositions and methods for treatment of fragile X syndrome |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| CN106562952B (zh) * | 2015-10-09 | 2020-06-09 | 江阴安博生物医药有限公司 | 氯胺酮在治疗重性抑郁障碍中的应用 |
| MX2019012285A (es) * | 2017-04-13 | 2020-11-06 | Ovid Therapeutics Inc | Metodos de tratamiento de encefalopatias del desarrollo. |
| EP3641742A2 (en) * | 2017-06-23 | 2020-04-29 | Develco Pharma Schweiz AG | Hydroxynorketamine for the use in the treatment of depression |
| PL3505157T3 (pl) | 2017-12-29 | 2022-04-11 | Celon Pharma S.A. | Kompozycja ketaminy w postaci suchego proszku do podawania dopłucnego w leczeniu depresji opornej na leczenie |
| CN118453559A (zh) | 2018-02-15 | 2024-08-09 | 国立大学法人千叶大学 | 炎症性疾病或骨病的预防或治疗剂及医药组合物 |
| US11426367B2 (en) | 2018-05-04 | 2022-08-30 | Perception Neuroscience, Inc. | Methods of treating substance abuse |
| PL3628313T3 (pl) | 2018-09-28 | 2025-06-23 | Novohale Therapeutics, Llc | Kompozycja ketaminy do zastosowania w sposobie leczenia depresji przez podawanie dopłucne |
| US20220062200A1 (en) * | 2019-05-07 | 2022-03-03 | Clexio Biosciences Ltd. | Abuse-deterrent dosage forms containing esketamine |
| WO2020239243A1 (en) | 2019-05-31 | 2020-12-03 | Celon Pharma S.A. | Electronically supervised administration of a pharmaceutical composition |
| EP3976145B1 (en) | 2019-05-31 | 2025-01-15 | Celon Pharma S.A. | An inhaler for electronically supervised parenteral administration of a pharmaceutical composition |
| US20220339123A1 (en) * | 2019-09-13 | 2022-10-27 | Janssen Pharmaceuticals, Inc. | Intranasal administration of esketamine |
| US11160799B2 (en) * | 2019-10-22 | 2021-11-02 | Cessatech A/S | Pediatric combination |
| TW202135787A (zh) * | 2019-12-12 | 2021-10-01 | 比利時商健生藥品公司 | 艾氯胺酮調配物及製備與儲存的方法 |
| EP4076410B1 (en) * | 2019-12-20 | 2025-09-10 | Alar Pharmaceuticals Inc. | Long-acting injectable formulations of ketamine pamoate salts |
| CN114903840A (zh) * | 2021-02-08 | 2022-08-16 | 四川普锐特药业有限公司 | 一种治疗抑郁症的低剂量r-氯胺酮经鼻药物 |
| CN113813250B (zh) * | 2021-07-21 | 2023-05-05 | 广州新济药业科技有限公司 | 含氯胺酮的药物组合物及其制备方法和应用 |
| CN116942647A (zh) * | 2022-04-26 | 2023-10-27 | 宜昌人福药业有限责任公司 | 艾司氯胺酮液体制剂及其用途 |
| US20250248951A1 (en) | 2022-04-26 | 2025-08-07 | Yichang Humanwell Pharmaceutical Co., Ltd. | Esketamine liquid preparation and use thereof |
| EP4629989A2 (en) * | 2022-12-07 | 2025-10-15 | Freedom Biosciences, Inc. | Treatment or prevention of depressive disorders through combination therapy |
| WO2025037252A1 (en) * | 2023-08-14 | 2025-02-20 | Javitt Daniel C | Compositions and methods for treatment of chronic pain and depression |
| US12005035B1 (en) * | 2023-08-14 | 2024-06-11 | Daniel C. Javitt | Compositions and methods for treatment of chronic pain and depression |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4312016A1 (de) | 1993-04-13 | 1994-10-20 | Goedecke Ag | Stabile Ketamin-Lösungen |
| AU2001291159A1 (en) * | 2000-09-20 | 2002-04-02 | Shahinian Jr., Lee | Self-preserved nasal, inhalable, and topical ophthalmic preparations and medications |
| US6881731B1 (en) | 2000-10-23 | 2005-04-19 | Shanbrom Technologies, Llc | Enhancers for microbiological disinfection |
| CN101466364A (zh) * | 2006-03-22 | 2009-06-24 | 纽约大学西奈山医学院 | 鼻内施用氯胺酮治疗抑郁症 |
| DE102007009888A1 (de) * | 2007-02-28 | 2008-09-04 | Hermann, Holger Lars, Dr. | Verwendung von S-(+)-Ketamin zur Behandlung von Depressionen |
| CN104902883A (zh) * | 2012-08-23 | 2015-09-09 | 斯图亚特·L·韦格 | 抗焦虑组合物、制剂及使用方法 |
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2014
- 2014-03-14 KR KR1020237037938A patent/KR20230156807A/ko not_active Ceased
- 2014-03-14 CN CN202310142376.5A patent/CN116251084A/zh active Pending
- 2014-03-14 RS RS20191043A patent/RS59130B1/sr unknown
- 2014-03-14 LT LTEP14719471.6T patent/LT2968221T/lt unknown
- 2014-03-14 PE PE2019002294A patent/PE20191796A1/es unknown
- 2014-03-14 ES ES14719471T patent/ES2745024T3/es active Active
- 2014-03-14 HU HUE14719471A patent/HUE045982T2/hu unknown
- 2014-03-14 MY MYPI2019005662A patent/MY203693A/en unknown
- 2014-03-14 MY MYPI2015703106A patent/MY191332A/en unknown
- 2014-03-14 PE PE2015001997A patent/PE20160052A1/es active IP Right Grant
- 2014-03-14 SI SI201431255T patent/SI2968221T1/sl unknown
- 2014-03-14 PT PT14719471T patent/PT2968221T/pt unknown
- 2014-03-14 US US14/212,988 patent/US20140275277A1/en not_active Abandoned
- 2014-03-14 DK DK14719471.6T patent/DK2968221T3/da active
- 2014-03-14 ME MEP-2019-229A patent/ME03465B/me unknown
- 2014-03-14 SG SG10201912735TA patent/SG10201912735TA/en unknown
- 2014-03-14 SG SG11201507358VA patent/SG11201507358VA/en unknown
- 2014-03-14 EP EP19151099.9A patent/EP3498268A1/en not_active Withdrawn
- 2014-03-14 PH PH1/2021/552333A patent/PH12021552333A1/en unknown
- 2014-03-14 EP EP14719471.6A patent/EP2968221B1/en not_active Revoked
- 2014-03-14 SM SM20190472T patent/SMT201900472T1/it unknown
- 2014-03-14 MX MX2015012342A patent/MX373678B/es active IP Right Grant
- 2014-03-14 MX MX2019000742A patent/MX386479B/es unknown
- 2014-03-14 KR KR1020157029474A patent/KR20150129023A/ko not_active Ceased
- 2014-03-14 HR HRP20191477 patent/HRP20191477T1/hr unknown
- 2014-03-14 EP EP23194654.2A patent/EP4309735A3/en active Pending
- 2014-03-14 PL PL14719471T patent/PL2968221T3/pl unknown
- 2014-03-14 CN CN201480015763.1A patent/CN105073103A/zh active Pending
- 2014-03-14 SG SG10201802106TA patent/SG10201802106TA/en unknown
- 2014-03-14 US US14/212,565 patent/US20140275276A1/en not_active Abandoned
- 2014-03-14 WO PCT/US2014/027074 patent/WO2014143646A1/en not_active Ceased
- 2014-03-14 NZ NZ712270A patent/NZ712270A/en unknown
- 2014-03-14 AU AU2014228324A patent/AU2014228324B2/en active Active
- 2014-03-14 KR KR1020217006306A patent/KR20210028278A/ko not_active Ceased
- 2014-03-14 CN CN201911264371.XA patent/CN111297803A/zh active Pending
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2015
- 2015-09-04 PH PH12015501957A patent/PH12015501957A1/en unknown
- 2015-09-11 CR CR20150480A patent/CR20150480A/es unknown
- 2015-09-15 CL CL2015002733A patent/CL2015002733A1/es unknown
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2019
- 2019-02-01 AU AU2019200702A patent/AU2019200702B2/en active Active
- 2019-02-01 AU AU2019200705A patent/AU2019200705B2/en active Active
- 2019-02-01 AU AU2019200696A patent/AU2019200696B2/en active Active
- 2019-08-23 CY CY20191100904T patent/CY1121928T1/el unknown
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2021
- 2021-01-07 AU AU2021200072A patent/AU2021200072A1/en not_active Abandoned
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2023
- 2023-02-20 AU AU2023200976A patent/AU2023200976B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |