PE20141688A1 - Combinacion farmaceutica antineuritica y composiciones - Google Patents
Combinacion farmaceutica antineuritica y composicionesInfo
- Publication number
- PE20141688A1 PE20141688A1 PE2014000973A PE2014000973A PE20141688A1 PE 20141688 A1 PE20141688 A1 PE 20141688A1 PE 2014000973 A PE2014000973 A PE 2014000973A PE 2014000973 A PE2014000973 A PE 2014000973A PE 20141688 A1 PE20141688 A1 PE 20141688A1
- Authority
- PE
- Peru
- Prior art keywords
- antineuritic
- compositions
- pharmaceutical combination
- vitamin
- hydroxocobalamine
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- FDJOLVPMNUYSCM-UVKKECPRSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7, Chemical compound [Co+3].N#[C-].C1([C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)[N-]\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O FDJOLVPMNUYSCM-UVKKECPRSA-L 0.000 abstract 2
- 235000004867 hydroxocobalamin Nutrition 0.000 abstract 2
- 239000011704 hydroxocobalamin Substances 0.000 abstract 2
- YOZNUFWCRFCGIH-BYFNXCQMSA-L hydroxocobalamin Chemical compound O[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O YOZNUFWCRFCGIH-BYFNXCQMSA-L 0.000 abstract 2
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 abstract 2
- -1 COMPRESSED Substances 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 230000003556 anti-epileptic effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 235000000639 cyanocobalamin Nutrition 0.000 abstract 1
- 239000011666 cyanocobalamin Substances 0.000 abstract 1
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- CTRLABGOLIVAIY-UHFFFAOYSA-N oxcarbazepine Chemical compound C1C(=O)C2=CC=CC=C2N(C(=O)N)C2=CC=CC=C21 CTRLABGOLIVAIY-UHFFFAOYSA-N 0.000 abstract 1
- 229960001816 oxcarbazepine Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- AYXYPKUFHZROOJ-ZETCQYMHSA-N pregabalin Chemical compound CC(C)C[C@H](CN)CC(O)=O AYXYPKUFHZROOJ-ZETCQYMHSA-N 0.000 abstract 1
- 229960001233 pregabalin Drugs 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) UN ANTIEPILEPTICO TAL COMO PREGABALINA EN UNA CANTIDAD DE 5MG A 600MG, U OXCARBAZEPINA EN UNA CANTIDAD DE 100MG A 2500MG; Y B) VITAMINAS SELECCIONADAS DE i) VITAMINA B12 TAL COMO CIANOCOBALAMINA O HIDROXOCOBALAMINA EN UNA CANTIDAD DE 50mcg A 1000mcg, O ii) VITAMINA B1 Y B12, DONDE LA VITAMINA B1 ES CLORHIDRATO O MONONITRATO DE TIAMINA EN UNA CANTIDAD DE 15MG A 750MG. DICHA COMPOSICION SE ENCUENTRA EN FORMA DE SUSPENSION, COMPRIMIDO, TABLETA, ENTRE OTROS, Y ES UTIL PARA EL TRATAMIENTO DEL DOLOR MODERADO A SEVERO Y NEURALGIAS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2011014042A MX336979B (es) | 2011-12-16 | 2011-12-16 | Combinacion farmaceutica antineuritica y composiciones. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20141688A1 true PE20141688A1 (es) | 2014-12-03 |
Family
ID=48611941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014000973A PE20141688A1 (es) | 2011-12-16 | 2012-12-14 | Combinacion farmaceutica antineuritica y composiciones |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140323428A1 (es) |
| BR (1) | BR112014014774A2 (es) |
| CA (1) | CA2859487C (es) |
| CL (1) | CL2014001581A1 (es) |
| CO (1) | CO6990712A2 (es) |
| CR (1) | CR20140283A (es) |
| DO (1) | DOP2014000134A (es) |
| ES (1) | ES2525952B1 (es) |
| GT (1) | GT201400115A (es) |
| MX (1) | MX336979B (es) |
| NI (1) | NI201400058A (es) |
| PE (1) | PE20141688A1 (es) |
| PL (1) | PL231163B1 (es) |
| WO (1) | WO2013088410A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2826470B1 (en) * | 2013-07-19 | 2017-09-06 | Arven Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of pregabalin |
| MX2014008336A (es) | 2014-07-07 | 2016-01-07 | Pptm Internat S A R L | Combinacion farmacologica antihiperalgesica, antialodinica y antiinflamatoria, composiciones farmaceuticas que la contienen, y su uso para el tratamiento del dolor neuropatico. |
| PE20251233A1 (es) | 2023-10-05 | 2025-04-29 | Laboratorios Silanes S A De C V | Tableta multiactivos en el tratamiento y control de dolor severo cronico y metodo de preparacion |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005065308A2 (en) * | 2003-12-29 | 2005-07-21 | Jason Mcdevitt | Compositions and methods to treat recurrent medical conditions |
| CA2701838A1 (en) * | 2007-10-09 | 2009-04-16 | Merck Patent Gmbh | Pharmaceutical compositions containing benfotiamine and one or more pharmaceutically active agents for the treatment of pain conditions of neuropathic origin |
| US8394759B2 (en) * | 2008-11-21 | 2013-03-12 | Cymbiotics, Inc. | Transdermal delivery of medicaments with combinations of cetylated fatty ester penetrant complexes |
-
2011
- 2011-12-16 MX MX2011014042A patent/MX336979B/es active IP Right Grant
-
2012
- 2012-12-14 US US14/365,988 patent/US20140323428A1/en not_active Abandoned
- 2012-12-14 BR BR112014014774A patent/BR112014014774A2/pt not_active Application Discontinuation
- 2012-12-14 WO PCT/IB2012/057345 patent/WO2013088410A1/es not_active Ceased
- 2012-12-14 CA CA2859487A patent/CA2859487C/en active Active
- 2012-12-14 PL PL409542A patent/PL231163B1/pl unknown
- 2012-12-14 PE PE2014000973A patent/PE20141688A1/es active IP Right Grant
- 2012-12-14 ES ES201490063A patent/ES2525952B1/es not_active Expired - Fee Related
-
2014
- 2014-06-16 CL CL2014001581A patent/CL2014001581A1/es unknown
- 2014-06-16 CO CO14129791A patent/CO6990712A2/es unknown
- 2014-06-16 GT GT201400115A patent/GT201400115A/es unknown
- 2014-06-16 DO DO2014000134A patent/DOP2014000134A/es unknown
- 2014-06-16 CR CR20140283A patent/CR20140283A/es unknown
- 2014-06-16 NI NI201400058A patent/NI201400058A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GT201400115A (es) | 2017-07-27 |
| ES2525952B1 (es) | 2015-10-05 |
| PL231163B1 (pl) | 2019-01-31 |
| US20140323428A1 (en) | 2014-10-30 |
| PL409542A1 (pl) | 2015-07-20 |
| CR20140283A (es) | 2015-03-11 |
| WO2013088410A1 (es) | 2013-06-20 |
| CA2859487C (en) | 2016-11-15 |
| BR112014014774A2 (pt) | 2017-06-13 |
| MX2011014042A (es) | 2013-06-17 |
| NI201400058A (es) | 2014-12-22 |
| CO6990712A2 (es) | 2014-07-10 |
| ES2525952A1 (es) | 2015-01-02 |
| CL2014001581A1 (es) | 2014-09-26 |
| CA2859487A1 (en) | 2013-06-20 |
| DOP2014000134A (es) | 2014-07-31 |
| MX336979B (es) | 2016-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |