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PE20081175A1 - Derivados de ftalazinona - Google Patents

Derivados de ftalazinona

Info

Publication number
PE20081175A1
PE20081175A1 PE2007001394A PE2007001394A PE20081175A1 PE 20081175 A1 PE20081175 A1 PE 20081175A1 PE 2007001394 A PE2007001394 A PE 2007001394A PE 2007001394 A PE2007001394 A PE 2007001394A PE 20081175 A1 PE20081175 A1 PE 20081175A1
Authority
PE
Peru
Prior art keywords
compound
phthalazinone
derivatives
fthalazin
cyclopropancarbonyl
Prior art date
Application number
PE2007001394A
Other languages
English (en)
Inventor
Keith Allan Menear
Anthony Peter Ottridge
Derek John Londesbrough
Michael Raymond Hallett
Keith Raymond Mulholland
John David Pittam
David Dermot Patrick
Ian Woodward Ashworth
Martin Francis Jones
Janette Helen Cherryman
Original Assignee
Kudos Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38952365&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20081175(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kudos Pharm Ltd filed Critical Kudos Pharm Ltd
Publication of PE20081175A1 publication Critical patent/PE20081175A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

REFERIDA AL COMPUESTO 4-[3-(4-CICLOPROPANCARBONIL-PIPERAZIN-1-CARBONIL)-4-FLUORO-BENCIL]-2H-FTALAZIN-1-ONA EN FORMA CRISTALINA A QUE TIENE PICOS CARACTERISTICOS EN UNA XRD DE POLVO DE 12,0, 17,8, 21,1, 22,3 Y 29,2. TAMBIEN ESTA REFERIDA A UN METODO DE PREPARACION Y A UNA COMPOSICION FARMACEUTICA. DICHO COMPUESTO TIENE ACTIVIDAD SOBRE LA POLI(ADP-RIBOSA)-POLIMERASA (PARP)
PE2007001394A 2006-10-17 2007-10-16 Derivados de ftalazinona PE20081175A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82969406P 2006-10-17 2006-10-17

Publications (1)

Publication Number Publication Date
PE20081175A1 true PE20081175A1 (es) 2008-11-06

Family

ID=38952365

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007001394A PE20081175A1 (es) 2006-10-17 2007-10-16 Derivados de ftalazinona

Country Status (34)

Country Link
US (2) US7692006B2 (es)
EP (3) EP2824098B1 (es)
JP (3) JP5248513B2 (es)
KR (2) KR20140011425A (es)
CN (3) CN104649979B (es)
AR (1) AR063320A1 (es)
AT (1) ATE528296T1 (es)
AU (1) AU2007311766B2 (es)
BR (1) BRPI0717125B8 (es)
CA (2) CA2875147C (es)
CL (1) CL2007002967A1 (es)
CO (1) CO6210728A2 (es)
CY (1) CY1112345T1 (es)
DK (1) DK2064189T3 (es)
ES (2) ES2587129T3 (es)
HR (1) HRP20120007T1 (es)
IL (2) IL197420A (es)
ME (1) ME01987B (es)
MX (1) MX2009004103A (es)
MY (2) MY162829A (es)
NO (2) NO341963B1 (es)
NZ (1) NZ575627A (es)
PE (1) PE20081175A1 (es)
PL (1) PL2064189T3 (es)
PT (1) PT2064189E (es)
RS (1) RS52112B (es)
RU (1) RU2465270C3 (es)
SA (2) SA07280551B1 (es)
SG (2) SG10201408404XA (es)
SI (1) SI2064189T1 (es)
TW (1) TWI404716B (es)
UA (1) UA97494C2 (es)
UY (1) UY30639A1 (es)
WO (1) WO2008047082A2 (es)

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CN105985294B (zh) * 2015-02-11 2020-12-25 四川科伦药物研究院有限公司 一种奥拉帕尼的制备方法
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