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PE20080353A1 - Sales de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-espiro[4,5]decan-2-ona y proceso de preparacion de las mismas - Google Patents

Sales de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-espiro[4,5]decan-2-ona y proceso de preparacion de las mismas

Info

Publication number
PE20080353A1
PE20080353A1 PE2007000415A PE2007000415A PE20080353A1 PE 20080353 A1 PE20080353 A1 PE 20080353A1 PE 2007000415 A PE2007000415 A PE 2007000415A PE 2007000415 A PE2007000415 A PE 2007000415A PE 20080353 A1 PE20080353 A1 PE 20080353A1
Authority
PE
Peru
Prior art keywords
phenyl
espiro
etoxy
decan
ona
Prior art date
Application number
PE2007000415A
Other languages
English (en)
Spanish (es)
Inventor
Mengwei Hu
Sunil Paliwal
Neng-Yang Shih
Frank B Guenter
Ingrid Mergelsberg
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE20080353A1 publication Critical patent/PE20080353A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PE2007000415A 2006-04-05 2007-04-04 Sales de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-espiro[4,5]decan-2-ona y proceso de preparacion de las mismas PE20080353A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78951306P 2006-04-05 2006-04-05

Publications (1)

Publication Number Publication Date
PE20080353A1 true PE20080353A1 (es) 2008-04-25

Family

ID=38470135

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007000415A PE20080353A1 (es) 2006-04-05 2007-04-04 Sales de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-espiro[4,5]decan-2-ona y proceso de preparacion de las mismas

Country Status (5)

Country Link
AR (1) AR060352A1 (fr)
CL (1) CL2007000947A1 (fr)
PE (1) PE20080353A1 (fr)
TW (1) TW200806666A (fr)
WO (1) WO2007114922A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG170838A1 (en) 2006-04-05 2011-05-30 Opko Health Inc Hydrochloride salts of 8-[{1-(3,5-bis-(trifluoromethyl) phenyl) -ethoxy}- methyl] -8-phenyl-1,7-diaza-spiro[4.5] decan-2-one and preparation process therefor
AR066191A1 (es) 2007-03-22 2009-08-05 Schering Corp Proceso e intermediarios para la sintesis de compuestos 8- [ ( 1- (3,5- bis- ( trifluorometil) fenil) - etoxi ) - metil]- 8 fenil - 1,7- diaza - espiro (4, 5) decan -2 ona
HUE026148T2 (en) * 2008-09-05 2016-05-30 Opko Health Inc 8 - ({1- [3,5-bis (trifluoromethyl) phenyl] ethoxy} methyl) -8-phenyl-1,7-diaza-spiro [4,5] decane-on-compounds intermediates
CN105017251B (zh) * 2015-06-30 2018-06-29 齐鲁制药有限公司 一种nk-1受体拮抗剂的制备方法及其中间体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030762A1 (es) * 2001-12-18 2003-09-05 Schering Corp Compuestos heterociclicos como antagonistas nk1
CA2550432A1 (fr) * 2003-12-22 2005-07-14 Schering Corporation Compositions pharmaceutiques

Also Published As

Publication number Publication date
CL2007000947A1 (es) 2008-01-25
TW200806666A (en) 2008-02-01
WO2007114922A2 (fr) 2007-10-11
WO2007114922A3 (fr) 2008-01-17
AR060352A1 (es) 2008-06-11

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