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PE20061160A1 - Sistema de administracion de farmacos con retencion gastrica - Google Patents

Sistema de administracion de farmacos con retencion gastrica

Info

Publication number
PE20061160A1
PE20061160A1 PE2005000334A PE2005000334A PE20061160A1 PE 20061160 A1 PE20061160 A1 PE 20061160A1 PE 2005000334 A PE2005000334 A PE 2005000334A PE 2005000334 A PE2005000334 A PE 2005000334A PE 20061160 A1 PE20061160 A1 PE 20061160A1
Authority
PE
Peru
Prior art keywords
agent
polymer
core
generating
tablet
Prior art date
Application number
PE2005000334A
Other languages
English (en)
Inventor
Nitin Bhalachandra Dharmadhikari
Yashoraj Rupsinh Zala
Original Assignee
Sun Pharmaceutical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Ind Ltd filed Critical Sun Pharmaceutical Ind Ltd
Publication of PE20061160A1 publication Critical patent/PE20061160A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013—Implantable devices or invasive measures
    • A61F5/003—Implantable devices or invasive measures inflatable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013—Implantable devices or invasive measures
    • A61F5/0036—Intragastrical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nursing (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

REFERIDA A UN SISTEMA DE ADMINISTRACION DE FARMACOS CON RETENCION GASTRICA EN LA FORMA DE UN COMPRIMIDO REVESTIDO QUE COMPRENDE: a) UN NUCLEO EN LA FORMA DE UN COMPRIMIDO QUE COMPRENDE UN AGENTE CAPAZ DE GENERAR PRESION INTERNA SOBRE LA CUBIERTA Y b) UN REVESTIMIENTO EXPANSIBLE FORMADO POR UNA COMPOSICION DE REVESTIMIENTO QUE COMPRENDE UN POLIMERO FORMADOR DE PELICULA Y UNO O MAS COMPONENTES EXPANSIBLES EN EL NUCLEO DEL COMPRIMIDO; ASIMISMO, DICHO SISTEMA COMPRENDE UNO O MAS AGENTES ACTIVOS QUE ESTAN PRESENTES EN EL NUCLEO Y EN EL REVESTIMIENTO. EL AGENTE CAPAZ DE GENERAR PRESION INTERNA SE SELECCIONA DE UN GENERADOR DE GAS, UN POLIMERO QUE AUMENTA RAPIDAMENTE DE TAMANO Y UN SUPERDESINTEGRANTE. EL AGENTE GENERADOR DE GAS PUEDE SER CARBONATOS, BICARBONATOS, SULFITOS, ENTRE OTROS, Y SE ENCUENTRA EN UNA CANTIDAD DE ENTRE 0,5% A 50% EN PESO DEL NUCLEO; DE PREFERENCIA DICHO AGENTE ES EL BICARBONATO DE SODIO. EL AGENTE EXPANSIBLE SE SELECCIONA DE UN AGENTE CAPAZ DE GENERAR GAS, UN POLIMERO QUE AUMENTA MUCHO DE TAMANO, UN SUPERDESINTEGRANTE Y LAS MEZCLAS DE LOS MISMOS; DONDE EL POLIMERO QUE AUMENTA MUCHO DE TAMANO PUEDE SER UN DERIVADO DE CELULOSA, POLIMEROS Y COPOLIMEROS DE ACIDO ACRILICO, ENTRE OTROS, Y SE ENCUENTRA EN UNA CANTIDAD DE ENTRE 0,5% A 40% EN PESO DE LA COMPOSICION DEL REVESTIMIENTO
PE2005000334A 2004-03-25 2005-03-23 Sistema de administracion de farmacos con retencion gastrica PE20061160A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN364MU2004 2004-03-25
IN1058MU2004 2004-10-07

Publications (1)

Publication Number Publication Date
PE20061160A1 true PE20061160A1 (es) 2006-11-12

Family

ID=35197425

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005000334A PE20061160A1 (es) 2004-03-25 2005-03-23 Sistema de administracion de farmacos con retencion gastrica

Country Status (21)

Country Link
US (1) US9439851B2 (es)
EP (1) EP1732522B1 (es)
JP (1) JP5166018B2 (es)
KR (1) KR101147666B1 (es)
CN (1) CN1960711A (es)
AP (1) AP2006003751A0 (es)
AR (1) AR048331A1 (es)
AU (1) AU2005235239B2 (es)
BR (1) BRPI0508744A (es)
CA (1) CA2561109C (es)
EA (1) EA011151B1 (es)
ES (1) ES2389729T3 (es)
IL (1) IL178054A (es)
MA (1) MA28542B1 (es)
MX (1) MXPA06010678A (es)
MY (1) MY148867A (es)
NZ (1) NZ549853A (es)
PE (1) PE20061160A1 (es)
PL (1) PL1732522T3 (es)
TW (1) TW200533391A (es)
WO (1) WO2005101983A2 (es)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7785291B2 (en) 2005-03-01 2010-08-31 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US7699863B2 (en) 2005-03-01 2010-04-20 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
BRPI0615410A2 (pt) * 2005-08-30 2013-02-13 Nicholas Piramal India Ltd composiÇço farmacÊutica de liberaÇço prolongada de metformina e processo para produÇço da mesma
US7674396B2 (en) * 2005-11-08 2010-03-09 Plensat Llc Method and system for treatment of eating disorders
AU2007201808B8 (en) * 2006-04-26 2013-09-05 Sun Pharmaceutical Advanced Research Company Ltd A method for alleviating signs and symptoms of spasticity
JP5220001B2 (ja) 2006-05-18 2013-06-26 チューリップ メディカル リミテッド 生体内分解性の自己展開式の胃内インプラントおよび胃以外のインプラント
US8765178B2 (en) 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
BRPI0622039B1 (pt) * 2006-09-26 2020-11-10 Plensat, Llc dispositivos gástricos ingeríveis de qualidade alimentícia
US20100081672A1 (en) * 2006-12-07 2010-04-01 Schering Corporation Ph sensitive matrix formulation
KR20080076382A (ko) * 2007-02-15 2008-08-20 (주)아모레퍼시픽 실로스타졸의 제어방출 제제 및 그 제조방법
CA2694602A1 (en) * 2007-07-27 2009-02-05 Depomed, Inc. Pulsatile gastric retentive dosage forms
WO2009022358A1 (en) * 2007-08-10 2009-02-19 Luigi Ambrosio Superabsorbent polymer hydro gels and a method of preparing thereof
WO2010020098A1 (zh) * 2008-08-18 2010-02-25 北京天衡药物研究院 胃滞留药物释出系统及其制备方法和用途
US20110171275A1 (en) * 2007-08-20 2011-07-14 Team Academy Of Pharmaceutical Science Gastroretentive drug delivery system, preparation method and use thereof
WO2010019915A1 (en) 2008-08-15 2010-02-18 Depomed Inc. Gastric retentive pharmaceutical compositions for treatment and prevention of cns disorders
FR2938431B1 (fr) 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
FR2949061B1 (fr) * 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
US20110200671A1 (en) 2010-02-17 2011-08-18 Sun Pharma Advanced Research Company Ltd. Method of treating a disease condition susceptible to baclofen therapy
EP2389933A1 (en) * 2010-05-25 2011-11-30 Sanovel Ilac Sanayi ve Ticaret A.S. Controlled-Release Pregabalin Compositions
BR112013003581B8 (pt) * 2010-08-18 2022-07-05 Evonik Roehm Gmbh Composição farmacêutica ou nutracêutica gastro resistente, que compreende um ou mais sais do ácido algínico, e seu processo de produção
AP3815A (en) 2010-12-22 2016-09-30 Purdue Pharma Lp Encased tamper resistant controlled release dosage forms
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
US20130017264A1 (en) * 2011-07-15 2013-01-17 Piramal Life Sciences Limited Alginate tube drug delivery system and method therefor
WO2013054285A1 (en) * 2011-10-11 2013-04-18 Ranbaxy Laboratories Limited A gastroretentive dosage system and process of preparation thereof
CN104334123B (zh) * 2012-06-07 2019-02-12 意比图密医疗有限公司 膨胀装置
RU2015110824A (ru) * 2012-08-27 2016-10-20 Эвоник Индустрис Аг Фармацевтическая или нутрицевтическая композиция с замедленным высвобождением и стойкостью к воздействию этанола
AU2012388440B2 (en) * 2012-08-27 2017-08-31 Evonik Operations Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
PE20151301A1 (es) 2013-02-05 2015-09-16 Purdue Pharma Lp Formulaciones farmaceuticas resistentes a la manipulacion indebida
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
BR112016012615B1 (pt) * 2013-12-05 2023-02-07 Epitomee Medical Ltd Sistemas, e kit
CN106061471A (zh) * 2014-02-17 2016-10-26 赢创罗姆有限公司 具有持续释放特性并针对乙醇的影响具有抗性的药物或营养组合物
KR101642193B1 (ko) * 2014-10-13 2016-07-25 씨제이헬스케어 주식회사 메트포르민 서방성 제제 및 그의 제조방법
EP3025709B1 (en) * 2014-11-27 2020-09-30 Capsugel Belgium NV Dosage form articles for external mucosal applications
SI3302444T1 (sl) 2015-06-05 2021-01-29 Evonik Operations Gmbh Farmacevtski ali nutracevtski sestavek z odpornostjo na vpliv etanola
EP3167879A1 (en) 2015-11-10 2017-05-17 Evonik Technochemie GmbH Gastric retention active delivery systems
ES2966736T3 (es) * 2016-12-02 2024-04-24 Clexio Biosciences Ltd Sistema de residencia gástrica
IL250090B (en) 2017-01-12 2018-10-31 Melcap Systems Ltd A capsule is intended for ingestion by a subject and a system is intended for the digestive system
JP7521897B2 (ja) 2017-03-31 2024-07-24 アキュラ・ファーマシューティカルズ・インコーポレーテッド 医薬品有効成分の自己調節放出のための方法及び組成物
JP6823539B2 (ja) * 2017-05-26 2021-02-03 株式会社ファンケル 胃内滞留性錠剤
CA3031412C (en) * 2017-06-16 2020-08-11 Kashiv Pharma Llc Gastroretentive dosage forms for sustained drug delivery
US10588863B2 (en) 2017-06-16 2020-03-17 Kashiv Biosciences, Llc Extended release compositions comprising pyridostigmine
US10987311B2 (en) 2017-06-16 2021-04-27 Kashiv Specialty Pharmaceuticals, Llc Extended release compositions comprising pyridostigmine
FR3068039B1 (fr) 2017-06-22 2020-07-10 Jellynov Composition auto-moussante en milieu acide et procede de preparation
WO2019022982A1 (en) 2017-07-26 2019-01-31 Verily Life Sciences Llc INGREDIENT INTRAGASTRIC BALLOON
US11337920B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Pharmaceutical composition comprising GHB gastro-retentive raft forming systems having trigger pulse drug release
CA3085941A1 (en) 2017-12-18 2019-06-27 Tris Pharma, Inc. Ghb pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
CA3086153A1 (en) 2017-12-18 2019-06-27 Tris Pharma, Inc. Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release
TW201929839A (zh) * 2017-12-29 2019-08-01 大陸商江蘇恒瑞醫藥股份有限公司 一種控釋藥物組合物及其製備方法
CN112118886B (zh) 2018-05-23 2022-08-23 上海汉都医药科技有限公司 活性药物成分的控释系统及其制备方法
CN114191307A (zh) 2020-09-17 2022-03-18 上海汉都医药科技有限公司 一种口腔滞留装置及其制备方法
US11911513B2 (en) 2018-05-23 2024-02-27 Shanghai Wd Pharmaceutical Co., Ltd Controlled-release system of active pharmaceutical ingredient and preparation method therefor
EP3824881B1 (en) 2018-06-18 2022-02-16 Amneal Complex Products Research LLC Extended release compositions comprising pyridostigmine
FR3089224B1 (fr) 2018-12-04 2020-12-11 Jellynov Composition auto-moussante en milieu acide et procédé de préparation
WO2020230089A1 (en) 2019-05-14 2020-11-19 Clexio Biosciences Ltd. Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
CN113116844A (zh) * 2019-12-31 2021-07-16 广州玻思韬控释药业有限公司 胃滞留片
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3786813A (en) 1972-12-27 1974-01-22 Alza Corp Drug delivery device with self actuated mechanism for retaining device in selected area
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4101650A (en) 1977-04-06 1978-07-18 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Pepstatin floating minicapsules
DE3681348D1 (de) 1985-06-11 1991-10-17 Teijin Ltd Oral-arzneizubereitung mit retardwirkung.
JPS62195323A (ja) 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
JPH0747534B2 (ja) 1986-06-02 1995-05-24 ロ−ラ−ジヤパン株式会社 錠 剤
IL87710A (en) 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
GB8722306D0 (en) * 1987-09-22 1987-10-28 Aps Research Ltd Sustained-release formulation
IT1245890B (it) * 1991-04-12 1994-10-25 Alfa Wassermann Spa Formulazioni farmaceutiche per uso orale gastroresistenti contenenti acidi biliari.
DE4406424A1 (de) 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
US5783212A (en) 1996-02-02 1998-07-21 Temple University--of the Commonwealth System of Higher Education Controlled release drug delivery system
KR100503266B1 (ko) 1997-01-14 2005-07-25 에르테에스 로만 테라피-시스테메 게엠베하 운트 코. 카게 위장관 내의 활성물질 방출을 조절하는, 팽창가능한 위장 체류성 치료장치
US5788987A (en) 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
SE9702533D0 (sv) 1997-07-01 1997-07-01 Astra Ab New oral formulation
IN186245B (es) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6350470B1 (en) * 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
DE19822278A1 (de) 1998-05-18 1999-12-02 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoff im Gastrointestinaltrakt mit verzögerter Pyloruspassage
FR2784583B1 (fr) 1998-10-16 2002-01-25 Synthelabo Composition pharmaceutique a residence gastrique et a liberation controlee
DE19850309A1 (de) 1998-10-30 2000-05-04 Lohmann Therapie Syst Lts Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer
JP2002535353A (ja) * 1999-01-29 2002-10-22 ロザン ファルマ ゲゼルシャフトミットベシュレンクテルハフツンク 医薬品組成物
WO2001010405A1 (en) * 1999-08-04 2001-02-15 Ranbaxy Laboratories Limited Hydrodynamically balanced oral drug delivery system
FR2797185B1 (fr) 1999-08-06 2001-10-26 Galenix Dev Composition pharmaceutique flottante comprenant une phase active et une phase non active
US6352721B1 (en) * 2000-01-14 2002-03-05 Osmotica Corp. Combined diffusion/osmotic pumping drug delivery system
JP2004501190A (ja) * 2000-06-23 2004-01-15 テバ　ファーマシューティカル　インダストリーズ　リミティド 治療薬の胃部保留および制御された放出のための急速膨張する組成物とその組成物を含む剤形
WO2003097018A1 (en) 2002-02-04 2003-11-27 Ranbaxy Laboratories Limited Hydrodynamically balancing oral drug delivery system with biphasic release
US20030008007A1 (en) 2001-04-23 2003-01-09 Jose Gutierrez-Rocca Release pharmaceutical construct for gastric retention
CA2452738C (en) * 2001-07-04 2011-06-14 Sun Pharmaceutical Industries Limited Gastric retention controlled drug delivery system
EP1416919A1 (en) * 2001-07-17 2004-05-12 Teva Pharmaceutical Industries Ltd. Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate
IN191024B (es) * 2001-09-25 2003-09-13 J B Chemicals And Pharmaceutic
JP2003306428A (ja) 2002-04-17 2003-10-28 Zensei Yakuhin Kogyo Kk 服用性を改善した硬カプセル剤
US20040180086A1 (en) * 2002-10-11 2004-09-16 Zebunnissa Ramtoola Gastro-retentive levodopa delivery form

Also Published As

Publication number Publication date
EA200601771A1 (ru) 2007-02-27
IL178054A (en) 2013-11-28
PL1732522T3 (pl) 2012-12-31
NZ549853A (en) 2009-12-24
KR101147666B1 (ko) 2012-05-22
AR048331A1 (es) 2006-04-19
AU2005235239B2 (en) 2011-06-23
JP2007530530A (ja) 2007-11-01
MA28542B1 (fr) 2007-04-03
EP1732522B1 (en) 2012-07-04
CA2561109C (en) 2012-09-18
KR20060126611A (ko) 2006-12-07
AU2005235239A1 (en) 2005-11-03
BRPI0508744A (pt) 2007-08-14
IL178054A0 (en) 2006-12-31
HK1094422A1 (en) 2007-03-30
US20080107732A1 (en) 2008-05-08
WO2005101983A2 (en) 2005-11-03
CA2561109A1 (en) 2005-11-03
US9439851B2 (en) 2016-09-13
EA011151B1 (ru) 2009-02-27
TW200533391A (en) 2005-10-16
MY148867A (en) 2013-06-14
EP1732522A2 (en) 2006-12-20
ES2389729T3 (es) 2012-10-30
AP2006003751A0 (en) 2006-10-31
CN1960711A (zh) 2007-05-09
WO2005101983A3 (en) 2006-04-27
MXPA06010678A (es) 2006-12-15
JP5166018B2 (ja) 2013-03-21

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