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PE20061115A1 - Anticuerpos anti-il-12, epitopos, composiciones, metodos y usos - Google Patents

Anticuerpos anti-il-12, epitopos, composiciones, metodos y usos

Info

Publication number
PE20061115A1
PE20061115A1 PE2006000036A PE2006000036A PE20061115A1 PE 20061115 A1 PE20061115 A1 PE 20061115A1 PE 2006000036 A PE2006000036 A PE 2006000036A PE 2006000036 A PE2006000036 A PE 2006000036A PE 20061115 A1 PE20061115 A1 PE 20061115A1
Authority
PE
Peru
Prior art keywords
epitops
antibodies
compositions
methods
refers
Prior art date
Application number
PE2006000036A
Other languages
English (en)
Inventor
Jill Giles-Komar
George Heavner
Jinquan Luo
Bernard Scallon
David Shealy
David Peritt
David M Knight
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of PE20061115A1 publication Critical patent/PE20061115A1/es

Links

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/5434—IL-12
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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Abstract

SE REFIERE A UN ANTICUERPO QUE SE UNE A UNA PORCION DE LA PROTEINA IL-12 QUE CORRESPONDE A POR LO MENOS UN RESIDUO DE AMINOACIDO SELECCIONADO EN LOS RESIDUOS 23, 40, 43, 45, 59 Y 62 DE LA SECUENCIA DE AMINOACIDOS DE LA SEC ID NO:9 Y TIENE UNA AFINIDAD SELECCIONADA ENTRE 10-9M, 10-10M, 10-11M, 10-12M. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE ADEMAS UN ANTAGONISTA TNF, UN ANTIRREUMATICO, UN RELAJADOR MUSCULAR, ANTIINFLAMATORIO, ENTRE OTROS, SIENDO UTILES EN EL TRATAMIENTO DE PSORIASIS, ESCLEROSIS MULTIPLE, ENFERMEDAD DE CROHN, ENTRE OTROS
PE2006000036A 2004-12-21 2006-01-03 Anticuerpos anti-il-12, epitopos, composiciones, metodos y usos PE20061115A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63781904P 2004-12-21 2004-12-21

Publications (1)

Publication Number Publication Date
PE20061115A1 true PE20061115A1 (es) 2006-10-12

Family

ID=36602254

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000036A PE20061115A1 (es) 2004-12-21 2006-01-03 Anticuerpos anti-il-12, epitopos, composiciones, metodos y usos

Country Status (22)

Country Link
US (8) US8080247B2 (es)
EP (1) EP1836294A4 (es)
JP (1) JP2008523842A (es)
KR (1) KR20070094927A (es)
CN (1) CN101120087A (es)
AR (1) AR051805A1 (es)
AU (1) AU2005319278A1 (es)
BR (1) BRPI0515858A (es)
CA (1) CA2591813A1 (es)
CR (1) CR9265A (es)
EA (1) EA016022B1 (es)
IL (1) IL183939A0 (es)
MY (1) MY157915A (es)
NI (1) NI200700155A (es)
NO (1) NO20073778L (es)
NZ (2) NZ555658A (es)
PE (1) PE20061115A1 (es)
SG (1) SG158150A1 (es)
TW (1) TWI406943B (es)
UY (1) UY29291A1 (es)
WO (1) WO2006069036A2 (es)
ZA (1) ZA200706036B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
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US6830751B1 (en) * 1994-03-14 2004-12-14 Genetics Institute, Llc Use of IL-12 antagonists in the treatment of rheumatoid arthritis
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