PE20020576A1 - Composiciones de medicamentos sobre la base de agentes anticolinergicos y corticoesteroides - Google Patents

Composiciones de medicamentos sobre la base de agentes anticolinergicos y corticoesteroides

Info

Publication number: PE20020576A1
Authority: PE; Peru
Prior art keywords: agents; holyphole; hiphole; sulphonate; vitamin
Prior art date: 2000-10-31

Application number

PE2001001073A

Other languages

English (en)

Spanish (es)

Inventor

Michel Pairet

Michael P Pieper

Christopher John Montague Meade

Richard Reichl

Christel Schmelzer

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-31

Filing date

2001-10-29

Publication date

2002-08-09

2000-12-15 Priority claimed from DE10062712A external-priority patent/DE10062712A1/de

2001-10-29 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2002-08-09 Publication of PE20020576A1 publication Critical patent/PE20020576A1/es

Links

239000000203 mixture Substances 0.000 title abstract 3
239000000812 cholinergic antagonist Substances 0.000 title abstract 2
239000003470 adrenal cortex hormone Substances 0.000 title 1
230000001078 anti-cholinergic effect Effects 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 3
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
-1 CYCLESONIDE Chemical compound 0.000 abstract 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 2
NNPPMTNAJDCUHE-UHFFFAOYSA-N isobutane Chemical compound CC(C)C NNPPMTNAJDCUHE-UHFFFAOYSA-N 0.000 abstract 2
239000011782 vitamin Substances 0.000 abstract 2
229930003231 vitamin Natural products 0.000 abstract 2
235000013343 vitamin Nutrition 0.000 abstract 2
229940088594 vitamin Drugs 0.000 abstract 2
150000003722 vitamin derivatives Chemical class 0.000 abstract 2
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 abstract 1
AFVFQIVMOAPDHO-UHFFFAOYSA-M Methanesulfonate Chemical compound CS([O-])(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-M 0.000 abstract 1
229940121948 Muscarinic receptor antagonist Drugs 0.000 abstract 1
229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 abstract 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
150000001298 alcohols Chemical class 0.000 abstract 1
239000003963 antioxidant agent Substances 0.000 abstract 1
239000011668 ascorbic acid Substances 0.000 abstract 1
235000010323 ascorbic acid Nutrition 0.000 abstract 1
229960005070 ascorbic acid Drugs 0.000 abstract 1
229960004495 beclometasone Drugs 0.000 abstract 1
NBMKJKDGKREAPL-DVTGEIKXSA-N beclomethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O NBMKJKDGKREAPL-DVTGEIKXSA-N 0.000 abstract 1
229960004436 budesonide Drugs 0.000 abstract 1
UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
150000002016 disaccharides Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229960000676 flunisolide Drugs 0.000 abstract 1
229960002714 fluticasone Drugs 0.000 abstract 1
MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 abstract 1
150000004676 glycans Chemical class 0.000 abstract 1
150000002334 glycols Chemical class 0.000 abstract 1
XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
239000001282 iso-butane Substances 0.000 abstract 1
229940126601 medicinal product Drugs 0.000 abstract 1
229960001664 mometasone Drugs 0.000 abstract 1
QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 abstract 1
IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 abstract 1
230000000414 obstructive effect Effects 0.000 abstract 1
229920001282 polysaccharide Polymers 0.000 abstract 1
239000005017 polysaccharide Substances 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1
238000004321 preservation Methods 0.000 abstract 1
JUJWROOIHBZHMG-UHFFFAOYSA-O pyridinium Chemical compound C1=CC=[NH+]C=C1 JUJWROOIHBZHMG-UHFFFAOYSA-O 0.000 abstract 1
MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 abstract 1
210000002345 respiratory system Anatomy 0.000 abstract 1
IXTCZMJQGGONPY-XJAYAHQCSA-N rofleponide Chemical compound C1([C@@H](F)C2)=CC(=O)CC[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3O[C@@H](CCC)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O IXTCZMJQGGONPY-XJAYAHQCSA-N 0.000 abstract 1
229950004432 rofleponide Drugs 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
150000005846 sugar alcohols Polymers 0.000 abstract 1
229910021653 sulphate ion Inorganic materials 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1
229930003799 tocopherol Natural products 0.000 abstract 1
239000011732 tocopherol Substances 0.000 abstract 1
235000019149 tocopherols Nutrition 0.000 abstract 1
JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical compound CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 abstract 1
229960005294 triamcinolone Drugs 0.000 abstract 1
GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Emergency Medicine (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)

PE2001001073A 2000-10-31 2001-10-29 Composiciones de medicamentos sobre la base de agentes anticolinergicos y corticoesteroides PE20020576A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10054042		2000-10-31
DE10062712A DE10062712A1 (de)	2000-12-15	2000-12-15	Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden

Publications (1)

Publication Number	Publication Date
PE20020576A1 true PE20020576A1 (es)	2002-08-09

Family

ID=26007540

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PE2001001073A PE20020576A1 (es)	2000-10-31	2001-10-29	Composiciones de medicamentos sobre la base de agentes anticolinergicos y corticoesteroides

Country Status (8)

Country	Link
EP (1)	EP1333830A2 (de)
JP (1)	JP2004512359A (de)
AU (1)	AU2002210575A1 (de)
CA (2)	CA2436540C (de)
MX (1)	MXPA03003751A (de)
PE (1)	PE20020576A1 (de)
UY (1)	UY26992A1 (de)
WO (1)	WO2002036106A2 (de)

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US7214687B2 (en)	1999-07-14	2007-05-08	Almirall Ag	Quinuclidine derivatives and medicinal compositions containing the same
ES2165768B1 (es)	1999-07-14	2003-04-01	Almirall Prodesfarma Sa	Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
SI1305329T2 (sl)	2000-08-05	2015-07-31	Glaxo Group Limited	S-fluorometil ester 6alfa,9alfa-difluoro-17alfa-(2-furanilkarboksil)oksi-11beta-hidroksi- 16alfa-metil-3-okso-androst-1,4-dien-17-karbotiojske kisline kot protivnetno sredstvo
GB0019172D0 (en)	2000-08-05	2000-09-27	Glaxo Group Ltd	Novel compounds
US6858596B2 (en)	2000-08-05	2005-02-22	Smithkline Beecham Corporation	Formulation containing anti-inflammatory androstane derivative
US6777399B2 (en)	2000-08-05	2004-08-17	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
CA2445839A1 (en)	2001-04-30	2002-11-07	Glaxo Group Limited	Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
US7244415B2 (en)	2002-03-28	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations of an anhydrate
US7311894B2 (en)	2002-03-28	2007-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations containing an anticholinergic
DE10214263A1 (de) *	2002-03-28	2003-10-16	Boehringer Ingelheim Pharma	HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum
US7084153B2 (en)	2002-04-12	2006-08-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments comprising steroids and a novel anticholinergic
DE10216429A1 (de) *	2002-04-12	2003-10-23	Boehringer Ingelheim Pharma	Arzneimittel enthaltend Steroide und ein neues Anticholinergikum
GB2389530B (en)	2002-06-14	2007-01-10	Cipla Ltd	Pharmaceutical compositions
US20040102469A1 (en) *	2002-09-13	2004-05-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Method for reducing the mortality rate
SI1765404T1 (sl)	2004-05-31	2009-04-30	Almirall Lab	Kombinacije, ki obsegajo antimuskarinska sredstva in beta-adrenergične agoniste
ES2257152B1 (es)	2004-05-31	2007-07-01	Laboratorios Almirall S.A.	Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
EP1763344A1 (de) *	2004-06-29	2007-03-21	Boehringer Ingelheim International GmbH	Medikamente zur inhalation mit steroiden und einem anticholinergikum
GB0523653D0 (en) *	2005-11-21	2005-12-28	Novartis Ag	Organic compounds
ES2298049B1 (es)	2006-07-21	2009-10-20	Laboratorios Almirall S.A.	Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
JP2010519195A (ja)	2007-02-19	2010-06-03	シプラ・リミテッド	薬学的組成物
EP2100599A1 (de) *	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2100598A1 (de) *	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
US8834931B2 (en)	2009-12-25	2014-09-16	Mahmut Bilgic	Dry powder formulation containing tiotropium for inhalation
TR200909792A2 (tr) *	2009-12-25	2011-07-21	B�Lg�� Mahmut	Tiotropyum, kortikosteroid ve bir kromoglisik asit türevi kombinasyonu içeren kuru toz kombinasyonu
TR200909789A2 (tr) *	2009-12-25	2011-07-21	B�Lg�� Mahmut	Tiotropyum, budesonid ve bir kromoglisik asit türevi kombinasyonu içeren kuru toz kombinasyonu
TR200909793A2 (tr) *	2009-12-25	2011-07-21	B�Lg�� Mahmut	Tiotropyum, mometazon ve bir kromoglisik asit türevi kombinasyonu içeren kuru toz kombinasyonu.
EP2510928A1 (de)	2011-04-15	2012-10-17	Almirall, S.A.	Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten
US20230270754A1 (en)	2020-07-31	2023-08-31	Chemo Research, S.L.	Combination therapy for inhalation administration

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EP0504112A3 (en) *	1991-03-14	1993-04-21	Ciba-Geigy Ag	Pharmaceutical aerosol formulations
DE19835346A1 (de) *	1998-08-05	2000-02-10	Boehringer Ingelheim Pharma	Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
GB0009606D0 (en) *	2000-04-18	2000-06-07	Glaxo Group Ltd	Therapeutic combinations
GB0009605D0 (en) *	2000-04-18	2000-06-07	Glaxo Group Ltd	Medicaments
GB0009592D0 (en) *	2000-04-18	2000-06-07	Glaxo Group Ltd	Respiratory combinations

2001
- 2001-10-23 AU AU2002210575A patent/AU2002210575A1/en not_active Abandoned
- 2001-10-23 WO PCT/EP2001/012511 patent/WO2002036106A2/de not_active Ceased
- 2001-10-23 MX MXPA03003751A patent/MXPA03003751A/es active IP Right Grant
- 2001-10-23 JP JP2002538918A patent/JP2004512359A/ja active Pending
- 2001-10-23 CA CA002436540A patent/CA2436540C/en not_active Expired - Fee Related
- 2001-10-23 EP EP01978463A patent/EP1333830A2/de not_active Ceased
- 2001-10-23 CA CA2733294A patent/CA2733294C/en not_active Expired - Fee Related
- 2001-10-29 PE PE2001001073A patent/PE20020576A1/es not_active Application Discontinuation
- 2001-10-29 UY UY26992A patent/UY26992A1/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2733294A1 (en)	2002-05-10
CA2436540C (en)	2008-01-29
AU2002210575A1 (en)	2002-05-15
WO2002036106A3 (de)	2002-09-19
CA2733294C (en)	2011-12-20
CA2436540A1 (en)	2002-05-10
EP1333830A2 (de)	2003-08-13
MXPA03003751A (es)	2004-10-15
UY26992A1 (es)	2002-06-20
WO2002036106A2 (de)	2002-05-10
JP2004512359A (ja)	2004-04-22

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Legal Events

Date	Code	Title	Description
2004-10-28	FA	Abandonment or withdrawal