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PE20011113A1 - CONTROLLED ORAL ADMINISTRATION SYSTEM FOR DAILY INGESTION OF CIPROFLOXACINE - Google Patents

CONTROLLED ORAL ADMINISTRATION SYSTEM FOR DAILY INGESTION OF CIPROFLOXACINE

Info

Publication number
PE20011113A1
PE20011113A1 PE2001000206A PE2001000206A PE20011113A1 PE 20011113 A1 PE20011113 A1 PE 20011113A1 PE 2001000206 A PE2001000206 A PE 2001000206A PE 2001000206 A PE2001000206 A PE 2001000206A PE 20011113 A1 PE20011113 A1 PE 20011113A1
Authority
PE
Peru
Prior art keywords
formulation
agent
less
weight
ciprofloxacine
Prior art date
Application number
PE2001000206A
Other languages
Spanish (es)
Inventor
Brij Khera
Gour Mukherji
Badri N Vishwanathan
John N Staniforth
Naresh Talwar
Ashok Rampal
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of PE20011113A1 publication Critical patent/PE20011113A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA FORMULACION DE LIBERACION CONTROLADA QUE COMPRENDE: a) UNA CANTIDAD EFECTIVA DE CIPROFLOXACINA; b) DE 0,1% A 8 % DE UN AGENTE DE VISCOSIDAD TAL COMO GOMA, ETERES DE CELULOSA DE PREFERENCIA GOMA XANTANO E HIDROXIPROPILCELULOSA Y/O UN AGENTE DE GELACION TAL COMO ALGINATO DE SODIO; c) DE 5% A 15% DE UNA AGENTE GENERADOR DE GAS TAL COMO BICARBONATO DE SODIO, CARBONATO DE CALCIO, CARBONATO DE SODIO Y; d) DE 3% A 15% DE UN AGENTE DE EXPANSION TAL COMO POLIVINILPIRROLIDONA , SIENDO TALES PORCENTAJES CON RELACION AL PESO/PESO DEL COMPUESTO. LA CIPROFLOXACINA SE LIBERA MAS DEL 50% DEL MEDICAMENTO EN MENOS DE 4 HORAS Y MAS DEL 60% DEL MEDICAMENTO EN MENOS DE 8 HORAS. LA FORMULACION COMPRENDE DE 100mg A 1000mg DE CIPROFLOXACINA Y EXCIPIENTES EN LA QUE EL PESO TOTAL DE LA FORMULACION CORRESPONDE A MENOS DE 2000mg. LA FORMULACION ES ADMINISTRADA VIA ORAL Y LA LIBERACION CONTROLADA DE CIPROFLOXACIONA SE PRODUCE EN EL ESTOMAGO O PARTE SUPERIOR DEL INTESTINOIT REFERS TO A CONTROLLED RELEASE FORMULATION THAT INCLUDES: a) AN EFFECTIVE AMOUNT OF CYPROFLOXACIN; b) FROM 0.1% TO 8% OF A VISCOSITY AGENT SUCH AS RUBBER, CELLULOSE ETHERS OF PREFERENCE XANTHANE GUM AND HYDROXYPROPYLCELLULOSE AND / OR A GELING AGENT SUCH AS SODIUM ALGINATE; c) FROM 5% TO 15% OF A GAS GENERATING AGENT SUCH AS SODIUM BICARBONATE, CALCIUM CARBONATE, SODIUM CARBONATE AND; d) FROM 3% TO 15% OF AN EXPANSION AGENT SUCH AS POLYVINYLPYRROLIDONE, SUCH PERCENTAGES IN RELATION TO THE WEIGHT / WEIGHT OF THE COMPOUND. CYPROFLOXACIN IS RELEASED MORE THAN 50% OF THE MEDICINE IN LESS THAN 4 HOURS AND MORE THAN 60% OF THE MEDICINE IN LESS THAN 8 HOURS. THE FORMULATION INCLUDES FROM 100mg TO 1000mg OF CIPROFLOXACIN AND EXCIPIENTS IN WHICH THE TOTAL WEIGHT OF THE FORMULATION CORRESPONDS TO LESS THAN 2000mg. THE FORMULATION IS ADMINISTERED VIA ORAL AND THE CONTROLLED RELEASE OF CIPROFLOXACIONA IS PRODUCED IN THE STOMACH OR UPPER PART OF THE INTESTINE

PE2001000206A 2000-03-03 2001-03-01 CONTROLLED ORAL ADMINISTRATION SYSTEM FOR DAILY INGESTION OF CIPROFLOXACINE PE20011113A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51788700A 2000-03-03 2000-03-03

Publications (1)

Publication Number Publication Date
PE20011113A1 true PE20011113A1 (en) 2001-10-14

Family

ID=24061635

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000206A PE20011113A1 (en) 2000-03-03 2001-03-01 CONTROLLED ORAL ADMINISTRATION SYSTEM FOR DAILY INGESTION OF CIPROFLOXACINE

Country Status (31)

Country Link
EP (1) EP1263409A1 (en)
JP (1) JP2003525229A (en)
KR (1) KR20030009374A (en)
CN (1) CN1420763A (en)
AP (2) AP2001002084A0 (en)
AR (1) AR032614A1 (en)
AU (1) AU3589701A (en)
BG (1) BG107055A (en)
BR (1) BR0108958A (en)
CA (1) CA2400950A1 (en)
CZ (1) CZ20022883A3 (en)
DO (1) DOP2001000130A (en)
EA (1) EA200200914A1 (en)
EC (1) ECSP013952A (en)
EE (1) EE200200497A (en)
GT (1) GT200100033A (en)
HN (1) HN2001000038A (en)
HR (1) HRP20020715A2 (en)
HU (1) HUP0204417A3 (en)
IL (1) IL151553A0 (en)
IS (1) IS6532A (en)
MX (1) MXPA02008568A (en)
NO (1) NO20024108L (en)
NZ (1) NZ520927A (en)
OA (1) OA12381A (en)
PE (1) PE20011113A1 (en)
PL (1) PL365071A1 (en)
SK (1) SK12542002A3 (en)
WO (1) WO2001064183A1 (en)
YU (1) YU66202A (en)
ZA (1) ZA200206764B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20030229101A1 (en) * 2002-06-06 2003-12-11 Sherman Bernard Charles Tablets comprising ciprofloxacin hydrochloride
DE10351448A1 (en) 2003-11-04 2005-06-09 Bayer Healthcare Ag Flavor-containing drug formulations with improved pharmaceutical properties
ATE396710T1 (en) * 2005-07-19 2008-06-15 Ethypharm Sa GASTRORETENTIVE COMPOSITIONS AND METHOD FOR PRODUCING
EP1880722B1 (en) * 2006-07-19 2010-03-17 Tabuk Pharmaceutical Manufacturing Co. Pharmaceutical compositions of ciprofloxacin
WO2016115253A1 (en) 2015-01-14 2016-07-21 The Regents Of The University Ofcolordo, A Body Corporate Insulin mimotopes and methods of using the same
US20190070299A1 (en) * 2016-02-23 2019-03-07 Matripharm International Inc. Dual-rate release formulation with high drug loading
US9820957B2 (en) 2016-03-24 2017-11-21 The Regents Of The University Of Colorado, A Body Corporate Methods of treating autoimmunity
US11052060B2 (en) 2018-02-12 2021-07-06 The Regents Of The University Of Colorado, A Body Corporate Compounds and methods for treating autoimmunity
US11013707B2 (en) 2018-03-23 2021-05-25 The Regents Of The University Of Colorado, A Body Corporate Administration of oral methyldopa
CN109806237A (en) * 2019-03-13 2019-05-28 悦康药业集团上海制药有限公司 A kind of Ciprofloxacin Lactate effervescent tablet and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096714A (en) * 1988-06-28 1992-03-17 Hauser-Kuhrts, Inc. Prolonged release drug tablet formulations
JPH0624959A (en) * 1991-10-04 1994-02-01 Bayer Yakuhin Kk Medice release solid pharmaceutical preparation of gastric suspending type sustained
DE4406424A1 (en) * 1994-02-28 1995-08-31 Bayer Ag Expandable dosage forms
DE19839057A1 (en) * 1998-08-28 2000-03-02 Koch Berthold Purge air controller for a drying device for compressed air
EA005767B1 (en) * 1998-09-14 2005-06-30 Рэнбакси Лабораториз Лимитед Pharmaceutical composition representing system of controlled delivery of a medicament for oral administration, providing time and local control

Also Published As

Publication number Publication date
CZ20022883A3 (en) 2003-04-16
HN2001000038A (en) 2005-03-23
HUP0204417A3 (en) 2005-03-29
CN1420763A (en) 2003-05-28
NO20024108L (en) 2002-10-25
DOP2001000130A (en) 2004-03-31
EE200200497A (en) 2004-02-16
ECSP013952A (en) 2002-04-23
EA200200914A1 (en) 2003-02-27
CA2400950A1 (en) 2001-09-07
PL365071A1 (en) 2004-12-27
AP1485A (en) 2005-10-31
JP2003525229A (en) 2003-08-26
MXPA02008568A (en) 2003-02-24
ZA200206764B (en) 2003-03-04
NZ520927A (en) 2003-06-30
KR20030009374A (en) 2003-01-29
AP2001002084A0 (en) 2001-03-31
EP1263409A1 (en) 2002-12-11
HRP20020715A2 (en) 2004-12-31
WO2001064183A1 (en) 2001-09-07
SK12542002A3 (en) 2003-05-02
AR032614A1 (en) 2003-11-19
NO20024108D0 (en) 2002-08-28
AU3589701A (en) 2001-09-12
GT200100033A (en) 2001-10-25
HUP0204417A2 (en) 2003-05-28
BG107055A (en) 2003-06-30
YU66202A (en) 2005-09-19
IS6532A (en) 2002-08-28
OA12381A (en) 2004-09-06
BR0108958A (en) 2003-09-30
AP2002002627A0 (en) 2002-09-30
IL151553A0 (en) 2003-04-10

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