PE20011092A1 - COMPOSITIONS FOR THE TOPICAL DELIVERY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED SKIN IRRITATION - Google Patents
COMPOSITIONS FOR THE TOPICAL DELIVERY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED SKIN IRRITATIONInfo
- Publication number
- PE20011092A1 PE20011092A1 PE2001000150A PE2001000150A PE20011092A1 PE 20011092 A1 PE20011092 A1 PE 20011092A1 PE 2001000150 A PE2001000150 A PE 2001000150A PE 2001000150 A PE2001000150 A PE 2001000150A PE 20011092 A1 PE20011092 A1 PE 20011092A1
- Authority
- PE
- Peru
- Prior art keywords
- compositions
- active agent
- pharmaceutically active
- skin irritation
- topical delivery
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 206010040880 Skin irritation Diseases 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 230000036556 skin irritation Effects 0.000 title 1
- 231100000475 skin irritation Toxicity 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004166 Lanolin Substances 0.000 abstract 1
- -1 PETROLATE Chemical compound 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 235000013871 bee wax Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003750 conditioning effect Effects 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 235000019388 lanolin Nutrition 0.000 abstract 1
- 229940039717 lanolin Drugs 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 239000012188 paraffin wax Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000012177 spermaceti Substances 0.000 abstract 1
- 229940084106 spermaceti Drugs 0.000 abstract 1
- BILPUZXRUDPOOF-UHFFFAOYSA-N stearyl palmitate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC BILPUZXRUDPOOF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UNA COMPOSICION QUE COMPRENDE: a) DE 1% A 50% EN PESO DE POR LO MENOS UN FOSFOLIPIDO TAL COMO FOSFOLIPIDOS INSATURADOS, PARCIALMENTE SATURADOS O SUS MEZCLAS DE PREFERENCIA LECITINA, FOSFATIDILCOLINA, FOSFADILETANOAMINA, FOSFATIDILSERINA, ENTRE OTROS ; b) DE 0,1% A 50% EN PESO DE POR LO MENOS UN AGENTE ACONDICIONADOR DE LA PIEL TAL COMO PETROLATO, PARAFINALIQUIDA, CERA DE PARAFINA, CERA DE ABEJAS , ESPERMACETI, ALCOHOL CETILICO, ENTRE OTROS, DE PREFERENCIA GLICERINA, PETROLATO, LANOLINA; c) DE 0,01% A 10% DE POR LO MENOS UN AGENTE FARMACEUTICAMNERTE ACTIVO; d) UN PORTADOR. LA COMPOSICIONES ES UTIL PARA PREVENIR O REDUCIR LA SEQUEDAD, IRRITACION, PRURITO EN LA PIELIT REFERS TO A COMPOSITION THAT INCLUDES: a) FROM 1% TO 50% BY WEIGHT OF AT LEAST ONE PHOSPHOLIPID SUCH AS UNSATURATED PHOSPHOLIPIDS, PARTIALLY SATURATED OR THEIR PREFERRED MIXTURES LECITHIN, PHOSPHATIDYLCOLINE, PHOSPHEROSTRYLETHANEANE; b) FROM 0.1% TO 50% BY WEIGHT OF AT LEAST ONE SKIN CONDITIONING AGENT SUCH AS PETROLATE, PARAFFINALIQUID, PARAFFIN WAX, BEE WAX, SPERMACETI, CETILIC ALCOHOL, AMONG OTHERS, PREFERRED GLYCERIN, PETROLATE, LANOLIN; c) FROM 0.01% TO 10% OF AT LEAST ONE ACTIVE PHARMACEUTICAL AGENT; d) A CARRIER. THE COMPOSITION IS USEFUL TO PREVENT OR REDUCE DRYING, IRRITATION, ITCHING OF THE SKIN
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50356800A | 2000-02-14 | 2000-02-14 | |
| US50316800A | 2000-02-14 | 2000-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20011092A1 true PE20011092A1 (en) | 2001-11-12 |
Family
ID=27054407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000150A PE20011092A1 (en) | 2000-02-14 | 2001-02-12 | COMPOSITIONS FOR THE TOPICAL DELIVERY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED SKIN IRRITATION |
Country Status (4)
| Country | Link |
|---|---|
| AU (1) | AU2001236996A1 (en) |
| CO (1) | CO5261579A1 (en) |
| PE (1) | PE20011092A1 (en) |
| WO (1) | WO2001060336A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020119173A1 (en) * | 2000-12-22 | 2002-08-29 | Lin Samuel Qcheng | Cosmetic compositions for preventing skin irritation |
| GB0704846D0 (en) * | 2007-03-13 | 2007-04-18 | Futura Medical Dev Ltd | Topical pharmaceutical formulation |
| PL214538B1 (en) * | 2009-05-28 | 2013-08-30 | P P F Hasco Lek Spolka Akcyjna | Liposome composition containing naproxen and a method for production of liposome composition containing naproxen |
| ES2985790T3 (en) * | 2013-05-03 | 2024-11-07 | Emollivet Ab | Topical composition and carrier for the administration of pharmaceutical or cosmetic active ingredients |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937078A (en) * | 1988-08-26 | 1990-06-26 | Mezei Associates Limited | Liposomal local anesthetic and analgesic products |
| DE4021084C1 (en) * | 1990-07-03 | 1991-11-21 | Hans Dr. 5024 Pulheim De Lautenschlaeger | Fumarate topical compsn. contg. liposome(s) improving bio-availability - esp. for treating psoriasis, contain liposomal structure, alcohol, stabiliser and fumaric acid (deriv.) and are stable and non irritant |
| US5766628A (en) * | 1992-02-24 | 1998-06-16 | Merz + Co. Gmbh & Co. | Bath and shower composition having vesicle-forming properties and method for the production and use thereof |
| EP0582239B1 (en) * | 1992-08-04 | 1999-08-04 | Rhone-Poulenc Rorer Gmbh | Pharmaceutical and/or cosmetic preparation |
| US5945409A (en) * | 1995-03-10 | 1999-08-31 | Wilson T. Crandall | Topical moisturizing composition and method |
-
2001
- 2001-02-12 PE PE2001000150A patent/PE20011092A1/en not_active Application Discontinuation
- 2001-02-13 AU AU2001236996A patent/AU2001236996A1/en not_active Abandoned
- 2001-02-13 WO PCT/US2001/004696 patent/WO2001060336A1/en not_active Ceased
- 2001-02-13 CO CO01010851A patent/CO5261579A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001236996A1 (en) | 2001-08-27 |
| CO5261579A1 (en) | 2003-03-31 |
| WO2001060336A1 (en) | 2001-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |