PE20001032A1 - Composiciones y metodos para tratar enfermedades pulmonares - Google Patents
Composiciones y metodos para tratar enfermedades pulmonaresInfo
- Publication number
- PE20001032A1 PE20001032A1 PE1999000856A PE00085699A PE20001032A1 PE 20001032 A1 PE20001032 A1 PE 20001032A1 PE 1999000856 A PE1999000856 A PE 1999000856A PE 00085699 A PE00085699 A PE 00085699A PE 20001032 A1 PE20001032 A1 PE 20001032A1
- Authority
- PE
- Peru
- Prior art keywords
- compositions
- methods
- pulmonary diseases
- treat pulmonary
- refers
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000019693 Lung disease Diseases 0.000 title abstract 2
- MSYGAHOHLUJIKV-UHFFFAOYSA-N 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester Chemical compound CC1=C(C(=O)OCC)C(C)=NN1C1=CC=CC([N+]([O-])=O)=C1 MSYGAHOHLUJIKV-UHFFFAOYSA-N 0.000 abstract 2
- 102000011017 Type 4 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 abstract 2
- 108010037584 Type 4 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 abstract 2
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 abstract 1
- 229960002848 formoterol Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN INHIBIDOR DE FOSFODIESTERASA 4 (PDE4) TAL COMO CIS-[4-CIANO-4-(3-CICLOPENTILOXI-4-METOXIFENIL)CICLOHEXAN-1-CARBOXILATO] Y UN BRONCODILATADOR ß-ADRENERGICO DE ACCION PROLONGADA TAL COMO FORMOTEROL. TAMBIEN SE REFIERE A UN METODO PARA PREPARAR LA COMPOSICION. LA COMPOSICION PUEDE SER UTIL PARA REDUCIR EL COMIENZO DE SINTOMAS DE UNA ENFERMEDAD PULMONAR
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9797398P | 1998-08-26 | 1998-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20001032A1 true PE20001032A1 (es) | 2000-11-10 |
Family
ID=22266001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000856A PE20001032A1 (es) | 1998-08-26 | 1999-08-25 | Composiciones y metodos para tratar enfermedades pulmonares |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6288118B1 (es) |
| EP (1) | EP1107747A4 (es) |
| JP (1) | JP2002523452A (es) |
| KR (1) | KR20010072931A (es) |
| CN (1) | CN1314811A (es) |
| AR (1) | AR022072A1 (es) |
| AU (1) | AU754379B2 (es) |
| BR (1) | BR9913152A (es) |
| CA (1) | CA2341488A1 (es) |
| CZ (1) | CZ293735B6 (es) |
| DZ (1) | DZ2876A1 (es) |
| HU (1) | HUP0103160A3 (es) |
| IL (1) | IL141335A0 (es) |
| MA (1) | MA26302A1 (es) |
| MY (1) | MY126544A (es) |
| NO (1) | NO20010882L (es) |
| NZ (1) | NZ527232A (es) |
| PE (1) | PE20001032A1 (es) |
| PL (1) | PL346271A1 (es) |
| TR (1) | TR200100500T2 (es) |
| WO (1) | WO2000012078A1 (es) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6525018B1 (en) * | 1999-05-17 | 2003-02-25 | The General Hospital Corp. | Treating eye disorders using intestinal trefoil proteins |
| US6624181B1 (en) | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
| US20030185838A1 (en) * | 2001-11-28 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating lesions of the respiratory epithelium |
| US20030186882A1 (en) * | 2001-07-31 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating and preventing distal bowel lesions |
| KR20010072931A (ko) * | 1998-08-26 | 2001-07-31 | 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 | 폐 질환 치료 요법 |
| US8933032B2 (en) | 1998-10-20 | 2015-01-13 | Children's Hospital Medical Center | Surfactant protein D for the treatment of disorders associated with lung injury |
| CZ302882B6 (cs) * | 1999-08-21 | 2012-01-04 | Nycomed Gmbh | Farmaceutický prostredek |
| PL358057A1 (en) | 2000-06-05 | 2004-08-09 | Altana Pharma Ag | Compounds effective as beta-2-adrenoreceptor agonists as well as pde4-inhibitors |
| US20040171544A1 (en) * | 2001-04-24 | 2004-09-02 | Barker Nicholas P. | Trefoil domain-containing polypeptides and uses thereof |
| US20030105016A1 (en) * | 2001-09-06 | 2003-06-05 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
| US20060189526A1 (en) * | 2002-04-24 | 2006-08-24 | Podolsky Daniel K | Compositions containing an intestinal trefoil peptide and a mucoadhesive |
| US7538082B2 (en) | 2001-04-24 | 2009-05-26 | The General Hospital Corporation | Methods and compositions for treating oral and esophageal lesions |
| US20030181384A1 (en) * | 2001-09-06 | 2003-09-25 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
| CA2462291A1 (en) * | 2001-10-05 | 2003-04-17 | The General Hospital Corporation | Methods and compositions for treating dermal lesions |
| US20030185839A1 (en) * | 2001-10-05 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating dermal lesions |
| US7931022B2 (en) * | 2001-10-19 | 2011-04-26 | Respirks, Inc. | Method and apparatus for dispensing inhalator medicament |
| MXPA04005053A (es) * | 2001-11-28 | 2004-09-10 | Gen Hospital Corp | Metodos y composiciones para tratar lesiones del epitelio respiratorio. |
| GB0129395D0 (en) * | 2001-12-07 | 2002-01-30 | Pfizer Ltd | Pharmaceutical combination |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| WO2003082196A2 (en) * | 2002-03-26 | 2003-10-09 | The General Hospital Corporation | Combination therapy using trefoil peptides |
| HRP20041160A2 (en) * | 2002-05-07 | 2005-08-31 | Altana Pharma Ag | Novel combination for the treatment of airway disorders |
| NZ536918A (en) * | 2002-05-07 | 2006-09-29 | Altana Pharma Ag | Combination of pantoprazole and a respiratory agent for the treatment of respiratory diseases |
| DE10220459A1 (de) * | 2002-05-07 | 2003-11-27 | Byk Gulden Lomberg Chem Fab | Neue Kombination zur Behandlung von Atemwegserkrankungen |
| DE10220458A1 (de) * | 2002-05-07 | 2003-11-27 | Altana Pharma Ag | Kombination zur Behandlung von Atemwegserkrankungen |
| US20060188471A1 (en) * | 2002-10-31 | 2006-08-24 | Podolsky Daniel K | Methods of treating epithelial lesions |
| WO2004047829A1 (en) * | 2002-11-27 | 2004-06-10 | Altana Pharma Ag | New synergistic combination comprising roflumilast and formoterol |
| PL214869B1 (pl) * | 2002-11-27 | 2013-09-30 | Nycomed Gmbh | Synergistyczna kombinacja zawierajaca roflumilast i (R, R)-formoterol |
| ES2335498T3 (es) | 2003-03-10 | 2010-03-29 | Nycomed Gmbh | Nuevo proceso para la preparacion de reflumilast. |
| JPWO2004087151A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 医薬組成物 |
| SE527200C2 (sv) * | 2003-06-19 | 2006-01-17 | Microdrug Ag | Inhalatoranordning samt kombinerade doser av formaterol och fluticason |
| EP1765331A4 (en) * | 2004-06-14 | 2007-12-05 | Sepracor Inc | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PULMONARY DISEASES |
| WO2005123071A1 (en) * | 2004-06-14 | 2005-12-29 | Sepracor Inc. | Methods of using albuterol and calcium activated potassium channel openers |
| EP2258350B1 (en) | 2005-03-16 | 2014-12-24 | Takeda GmbH | Taste masked dosage form containing roflumilast |
| DE102005030733A1 (de) * | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff |
| US20080254029A1 (en) * | 2007-04-11 | 2008-10-16 | Alcon Research, Ltd. | Use of an Inhibitor of TNFa Plus an Antihistamine to Treat Allergic Rhinitis and Allergic Conjunctivitis |
| US20090182035A1 (en) * | 2007-04-11 | 2009-07-16 | Alcon Research, Ltd. | Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis |
| ES2618881T3 (es) * | 2009-04-22 | 2017-06-22 | Indiana University Research And Technology Corporation | Colágeno V para su uso en el tratamiento del asma |
| CN102548536A (zh) * | 2009-10-01 | 2012-07-04 | 爱尔康研究有限公司 | 奥洛他定组合物及其用途 |
| KR101035488B1 (ko) * | 2009-10-05 | 2011-05-20 | 숭실대학교산학협력단 | 자동차 블랙박스 영상물 수집 방법 |
| US8771693B2 (en) | 2009-10-27 | 2014-07-08 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
| AU2011253203A1 (en) * | 2010-05-10 | 2012-11-22 | Gilead Sciences, Inc. | Bifunctional quinoline derivatives |
| WO2011143106A1 (en) | 2010-05-10 | 2011-11-17 | Gilead Sciences, Inc. | Bi - functional pyrazolopyridine compounds |
| WO2012149334A2 (en) | 2011-04-27 | 2012-11-01 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
| WO2015063669A1 (en) | 2013-10-30 | 2015-05-07 | Wockhardt Limited | Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof |
| US10433624B2 (en) * | 2015-03-26 | 2019-10-08 | Nike, Inc. | Duffel bag |
| US11866482B2 (en) | 2018-02-07 | 2024-01-09 | Duke University | System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791025A (fr) | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | Composes heterocycliques |
| GB1457873A (en) | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
| FR2390164A1 (fr) | 1977-05-13 | 1978-12-08 | Blanie Paul | Association a action anti-asthmatique |
| US5602110A (en) | 1994-08-31 | 1997-02-11 | Case Western Reserve University | Method and composition for treating cystic fibrosis |
| FR2753706B1 (fr) * | 1996-09-20 | 1998-10-30 | Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant | |
| FR2753969B1 (fr) | 1996-09-27 | 1998-10-30 | Adir | Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP2001513097A (ja) * | 1997-02-28 | 2001-08-28 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | Pde−抑制物質とアデニル酸シクラーゼ・アゴニストもしくはグアニル酸シクラーゼ・アゴニストとからなる相乗的組み合わせ組成物 |
| US5858694A (en) * | 1997-05-30 | 1999-01-12 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of cancerous lesions |
| KR20010072931A (ko) * | 1998-08-26 | 2001-07-31 | 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 | 폐 질환 치료 요법 |
-
1999
- 1999-08-24 KR KR1020017002358A patent/KR20010072931A/ko not_active Ceased
- 1999-08-24 CN CN99810111A patent/CN1314811A/zh active Pending
- 1999-08-24 CA CA002341488A patent/CA2341488A1/en not_active Abandoned
- 1999-08-24 IL IL14133599A patent/IL141335A0/xx unknown
- 1999-08-24 EP EP99941248A patent/EP1107747A4/en not_active Withdrawn
- 1999-08-24 NZ NZ527232A patent/NZ527232A/en unknown
- 1999-08-24 JP JP2000567196A patent/JP2002523452A/ja active Pending
- 1999-08-24 BR BR9913152-8A patent/BR9913152A/pt not_active IP Right Cessation
- 1999-08-24 PL PL99346271A patent/PL346271A1/xx unknown
- 1999-08-24 US US09/763,516 patent/US6288118B1/en not_active Expired - Fee Related
- 1999-08-24 MY MYPI99003615A patent/MY126544A/en unknown
- 1999-08-24 AU AU54939/99A patent/AU754379B2/en not_active Ceased
- 1999-08-24 WO PCT/US1999/019332 patent/WO2000012078A1/en not_active Ceased
- 1999-08-24 TR TR2001/00500T patent/TR200100500T2/xx unknown
- 1999-08-24 CZ CZ2001692A patent/CZ293735B6/cs not_active IP Right Cessation
- 1999-08-24 DZ DZ990176A patent/DZ2876A1/xx active
- 1999-08-24 HU HU0103160A patent/HUP0103160A3/hu unknown
- 1999-08-25 MA MA25745A patent/MA26302A1/fr unknown
- 1999-08-25 PE PE1999000856A patent/PE20001032A1/es not_active Application Discontinuation
- 1999-09-03 AR ARP990104234A patent/AR022072A1/es not_active Application Discontinuation
-
2001
- 2001-02-21 NO NO20010882A patent/NO20010882L/no not_active Application Discontinuation
- 2001-08-20 US US09/933,455 patent/US6555583B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1314811A (zh) | 2001-09-26 |
| EP1107747A1 (en) | 2001-06-20 |
| US6555583B2 (en) | 2003-04-29 |
| AU5493999A (en) | 2000-03-21 |
| MA26302A1 (fr) | 2004-10-01 |
| AU754379B2 (en) | 2002-11-14 |
| CZ2001692A3 (cs) | 2002-02-13 |
| US20010056122A1 (en) | 2001-12-27 |
| BR9913152A (pt) | 2001-05-15 |
| HUP0103160A2 (hu) | 2002-01-28 |
| IL141335A0 (en) | 2002-03-10 |
| NO20010882D0 (no) | 2001-02-21 |
| MY126544A (en) | 2006-10-31 |
| CZ293735B6 (cs) | 2004-07-14 |
| WO2000012078A1 (en) | 2000-03-09 |
| JP2002523452A (ja) | 2002-07-30 |
| AR022072A1 (es) | 2002-09-04 |
| US6288118B1 (en) | 2001-09-11 |
| EP1107747A4 (en) | 2003-04-23 |
| NZ527232A (en) | 2005-03-24 |
| TR200100500T2 (tr) | 2001-06-21 |
| NO20010882L (no) | 2001-02-21 |
| DZ2876A1 (fr) | 2003-12-15 |
| PL346271A1 (en) | 2002-01-28 |
| KR20010072931A (ko) | 2001-07-31 |
| CA2341488A1 (en) | 2000-03-09 |
| HUP0103160A3 (en) | 2002-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |