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PE20001032A1 - Composiciones y metodos para tratar enfermedades pulmonares - Google Patents

Composiciones y metodos para tratar enfermedades pulmonares

Info

Publication number
PE20001032A1
PE20001032A1 PE1999000856A PE00085699A PE20001032A1 PE 20001032 A1 PE20001032 A1 PE 20001032A1 PE 1999000856 A PE1999000856 A PE 1999000856A PE 00085699 A PE00085699 A PE 00085699A PE 20001032 A1 PE20001032 A1 PE 20001032A1
Authority
PE
Peru
Prior art keywords
compositions
methods
pulmonary diseases
treat pulmonary
refers
Prior art date
Application number
PE1999000856A
Other languages
English (en)
Inventor
Theodore J Torphy
Anthony S Rebuck
Richard Nieman
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PE20001032A1 publication Critical patent/PE20001032A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN INHIBIDOR DE FOSFODIESTERASA 4 (PDE4) TAL COMO CIS-[4-CIANO-4-(3-CICLOPENTILOXI-4-METOXIFENIL)CICLOHEXAN-1-CARBOXILATO] Y UN BRONCODILATADOR ß-ADRENERGICO DE ACCION PROLONGADA TAL COMO FORMOTEROL. TAMBIEN SE REFIERE A UN METODO PARA PREPARAR LA COMPOSICION. LA COMPOSICION PUEDE SER UTIL PARA REDUCIR EL COMIENZO DE SINTOMAS DE UNA ENFERMEDAD PULMONAR
PE1999000856A 1998-08-26 1999-08-25 Composiciones y metodos para tratar enfermedades pulmonares PE20001032A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9797398P 1998-08-26 1998-08-26

Publications (1)

Publication Number Publication Date
PE20001032A1 true PE20001032A1 (es) 2000-11-10

Family

ID=22266001

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999000856A PE20001032A1 (es) 1998-08-26 1999-08-25 Composiciones y metodos para tratar enfermedades pulmonares

Country Status (21)

Country Link
US (2) US6288118B1 (es)
EP (1) EP1107747A4 (es)
JP (1) JP2002523452A (es)
KR (1) KR20010072931A (es)
CN (1) CN1314811A (es)
AR (1) AR022072A1 (es)
AU (1) AU754379B2 (es)
BR (1) BR9913152A (es)
CA (1) CA2341488A1 (es)
CZ (1) CZ293735B6 (es)
DZ (1) DZ2876A1 (es)
HU (1) HUP0103160A3 (es)
IL (1) IL141335A0 (es)
MA (1) MA26302A1 (es)
MY (1) MY126544A (es)
NO (1) NO20010882L (es)
NZ (1) NZ527232A (es)
PE (1) PE20001032A1 (es)
PL (1) PL346271A1 (es)
TR (1) TR200100500T2 (es)
WO (1) WO2000012078A1 (es)

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US20030185838A1 (en) * 2001-11-28 2003-10-02 Podolsky Daniel K. Methods and compositions for treating lesions of the respiratory epithelium
US20030186882A1 (en) * 2001-07-31 2003-10-02 Podolsky Daniel K. Methods and compositions for treating and preventing distal bowel lesions
KR20010072931A (ko) * 1998-08-26 2001-07-31 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 폐 질환 치료 요법
US8933032B2 (en) 1998-10-20 2015-01-13 Children's Hospital Medical Center Surfactant protein D for the treatment of disorders associated with lung injury
CZ302882B6 (cs) * 1999-08-21 2012-01-04 Nycomed Gmbh Farmaceutický prostredek
PL358057A1 (en) 2000-06-05 2004-08-09 Altana Pharma Ag Compounds effective as beta-2-adrenoreceptor agonists as well as pde4-inhibitors
US20040171544A1 (en) * 2001-04-24 2004-09-02 Barker Nicholas P. Trefoil domain-containing polypeptides and uses thereof
US20030105016A1 (en) * 2001-09-06 2003-06-05 Podolsky Daniel K. Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions
US20060189526A1 (en) * 2002-04-24 2006-08-24 Podolsky Daniel K Compositions containing an intestinal trefoil peptide and a mucoadhesive
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
US20030181384A1 (en) * 2001-09-06 2003-09-25 Podolsky Daniel K. Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions
CA2462291A1 (en) * 2001-10-05 2003-04-17 The General Hospital Corporation Methods and compositions for treating dermal lesions
US20030185839A1 (en) * 2001-10-05 2003-10-02 Podolsky Daniel K. Methods and compositions for treating dermal lesions
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
MXPA04005053A (es) * 2001-11-28 2004-09-10 Gen Hospital Corp Metodos y composiciones para tratar lesiones del epitelio respiratorio.
GB0129395D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
WO2003082196A2 (en) * 2002-03-26 2003-10-09 The General Hospital Corporation Combination therapy using trefoil peptides
HRP20041160A2 (en) * 2002-05-07 2005-08-31 Altana Pharma Ag Novel combination for the treatment of airway disorders
NZ536918A (en) * 2002-05-07 2006-09-29 Altana Pharma Ag Combination of pantoprazole and a respiratory agent for the treatment of respiratory diseases
DE10220459A1 (de) * 2002-05-07 2003-11-27 Byk Gulden Lomberg Chem Fab Neue Kombination zur Behandlung von Atemwegserkrankungen
DE10220458A1 (de) * 2002-05-07 2003-11-27 Altana Pharma Ag Kombination zur Behandlung von Atemwegserkrankungen
US20060188471A1 (en) * 2002-10-31 2006-08-24 Podolsky Daniel K Methods of treating epithelial lesions
WO2004047829A1 (en) * 2002-11-27 2004-06-10 Altana Pharma Ag New synergistic combination comprising roflumilast and formoterol
PL214869B1 (pl) * 2002-11-27 2013-09-30 Nycomed Gmbh Synergistyczna kombinacja zawierajaca roflumilast i (R, R)-formoterol
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
JPWO2004087151A1 (ja) * 2003-03-31 2006-06-29 協和醗酵工業株式会社 医薬組成物
SE527200C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser av formaterol och fluticason
EP1765331A4 (en) * 2004-06-14 2007-12-05 Sepracor Inc METHODS AND COMPOSITIONS FOR THE TREATMENT OF PULMONARY DISEASES
WO2005123071A1 (en) * 2004-06-14 2005-12-29 Sepracor Inc. Methods of using albuterol and calcium activated potassium channel openers
EP2258350B1 (en) 2005-03-16 2014-12-24 Takeda GmbH Taste masked dosage form containing roflumilast
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
US20080254029A1 (en) * 2007-04-11 2008-10-16 Alcon Research, Ltd. Use of an Inhibitor of TNFa Plus an Antihistamine to Treat Allergic Rhinitis and Allergic Conjunctivitis
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
ES2618881T3 (es) * 2009-04-22 2017-06-22 Indiana University Research And Technology Corporation Colágeno V para su uso en el tratamiento del asma
CN102548536A (zh) * 2009-10-01 2012-07-04 爱尔康研究有限公司 奥洛他定组合物及其用途
KR101035488B1 (ko) * 2009-10-05 2011-05-20 숭실대학교산학협력단 자동차 블랙박스 영상물 수집 방법
US8771693B2 (en) 2009-10-27 2014-07-08 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
AU2011253203A1 (en) * 2010-05-10 2012-11-22 Gilead Sciences, Inc. Bifunctional quinoline derivatives
WO2011143106A1 (en) 2010-05-10 2011-11-17 Gilead Sciences, Inc. Bi - functional pyrazolopyridine compounds
WO2012149334A2 (en) 2011-04-27 2012-11-01 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof
US10433624B2 (en) * 2015-03-26 2019-10-08 Nike, Inc. Duffel bag
US11866482B2 (en) 2018-02-07 2024-01-09 Duke University System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators

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BE791025A (fr) 1971-11-19 1973-05-07 Allen & Hanburys Ltd Composes heterocycliques
GB1457873A (en) 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
FR2390164A1 (fr) 1977-05-13 1978-12-08 Blanie Paul Association a action anti-asthmatique
US5602110A (en) 1994-08-31 1997-02-11 Case Western Reserve University Method and composition for treating cystic fibrosis
FR2753706B1 (fr) * 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR2753969B1 (fr) 1996-09-27 1998-10-30 Adir Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2001513097A (ja) * 1997-02-28 2001-08-28 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング Pde−抑制物質とアデニル酸シクラーゼ・アゴニストもしくはグアニル酸シクラーゼ・アゴニストとからなる相乗的組み合わせ組成物
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
KR20010072931A (ko) * 1998-08-26 2001-07-31 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 폐 질환 치료 요법

Also Published As

Publication number Publication date
CN1314811A (zh) 2001-09-26
EP1107747A1 (en) 2001-06-20
US6555583B2 (en) 2003-04-29
AU5493999A (en) 2000-03-21
MA26302A1 (fr) 2004-10-01
AU754379B2 (en) 2002-11-14
CZ2001692A3 (cs) 2002-02-13
US20010056122A1 (en) 2001-12-27
BR9913152A (pt) 2001-05-15
HUP0103160A2 (hu) 2002-01-28
IL141335A0 (en) 2002-03-10
NO20010882D0 (no) 2001-02-21
MY126544A (en) 2006-10-31
CZ293735B6 (cs) 2004-07-14
WO2000012078A1 (en) 2000-03-09
JP2002523452A (ja) 2002-07-30
AR022072A1 (es) 2002-09-04
US6288118B1 (en) 2001-09-11
EP1107747A4 (en) 2003-04-23
NZ527232A (en) 2005-03-24
TR200100500T2 (tr) 2001-06-21
NO20010882L (no) 2001-02-21
DZ2876A1 (fr) 2003-12-15
PL346271A1 (en) 2002-01-28
KR20010072931A (ko) 2001-07-31
CA2341488A1 (en) 2000-03-09
HUP0103160A3 (en) 2002-11-28

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